pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers
Tipping, Kevin W., Karamanos, Theodoros K., Jakhria, Toral, Iadanza, Matthew G., Goodchild, Sophia C., Tuma, Roman, Ranson, Neil A., Hewitt, Eric W., Radford, Sheena E.
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
Get full text
Journal Article
β2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH
Goodchild, Sophia C, Sheynis, Tania, Thompson, Rebecca, Tipping, Kevin W, Xue, Wei-Feng, Ranson, Neil A, Beales, Paul A, Hewitt, Eric W, Radford, Sheena E
Published in PloS one (06.08.2014)
Published in PloS one (06.08.2014)
Get full text
Journal Article
Aggregation Modulators Interfere with Membrane Interactions of β2-Microglobulin Fibrils
Sheynis, Tania, Friediger, Anat, Xue, Wei-Feng, Hellewell, Andrew L., Tipping, Kevin W., Hewitt, Eric W., Radford, Sheena E., Jelinek, Raz
Published in Biophysical journal (06.08.2013)
Published in Biophysical journal (06.08.2013)
Get full text
Journal Article
β2-Microglobulin Amyloid Fibrils Are Nanoparticles That Disrupt Lysosomal Membrane Protein Trafficking and Inhibit Protein Degradation by Lysosomes
Jakhria, Toral, Hellewell, Andrew L., Porter, Morwenna Y., Jackson, Matthew P., Tipping, Kevin W., Xue, Wei-Feng, Radford, Sheena E., Hewitt, Eric W.
Published in The Journal of biological chemistry (26.12.2014)
Published in The Journal of biological chemistry (26.12.2014)
Get full text
Journal Article
sub.2-Microglobulin Amyloid Fibril-Induced Membrane Disruption Is Enhanced by Endosomal Lipids and Acidic pH
Goodchild, Sophia C, Sheynis, Tania, Thompson, Rebecca, Tipping, Kevin W, Xue, Wei-Feng, Ranson, Neil A, Beales, Paul A, Hewitt, Eric W, Radford, Sheena E
Published in PloS one (06.08.2014)
Published in PloS one (06.08.2014)
Get full text
Journal Article
beta 2-Microglobulin Amyloid Fibrils Are Nanoparticles That Disrupt Lysosomal Membrane Protein Trafficking and Inhibit Protein Degradation by Lysosomes
Jakhria, Toral, Hellewell, Andrew L, Porter, Morwenna Y, Jackson, Matthew P, Tipping, Kevin W, Xue, Wei-Feng, Radford, Sheena E, Hewitt, Eric W
Published in The Journal of biological chemistry (05.01.2014)
Published in The Journal of biological chemistry (05.01.2014)
Get full text
Journal Article
Aggregation Modulators Interfere with Membrane Interactions of [Beta]^sub 2^-Microglobulin Fibrils
Sheynis, Tania, Friediger, Anat, Xue, Wei-Feng, Hellewell, Andrew L, Tipping, Kevin W, Hewitt, Eric W, Radford, Sheena E, Jelinek, Raz
Published in Biophysical journal (06.08.2013)
Get full text
Published in Biophysical journal (06.08.2013)
Journal Article