CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
Legarda, Diana, Justus, Scott J., Ang, Rosalind L., Rikhi, Nimisha, Li, Wenjing, Moran, Thomas M., Zhang, Jianke, Mizoguchi, Emiko, Zelic, Matija, Kelliher, Michelle A., Blander, J. Magarian, Ting, Adrian T.
Published in Cell reports (Cambridge) (14.06.2016)
Published in Cell reports (Cambridge) (14.06.2016)
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Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death
Ang, Rosalind L., Chan, Mark, Legarda, Diana, Sundberg, John P., Sun, Shao-Cong, Gillespie, Virginia L., Chun, Nicholas, Heeger, Peter S., Xiong, Huabao, Lira, Sergio A., Ting, Adrian T.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
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Journal Article
Analysis of Necroptosis in Bone Marrow-Derived Macrophages
Legarda, Diana, Ting, Adrian T
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
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Journal Article
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1
O'Donnell, Marie Anne, Hase, Hidenori, Legarda, Diana, Ting, Adrian T
Published in PloS one (26.07.2012)
Published in PloS one (26.07.2012)
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Two Coordinated Mechanisms Underlie Tumor Necrosis Factor Alpha-Induced Immediate and Delayed IκB Kinase Activation
Blackwell, Ken, Zhang, Laiqun, Workman, Lauren M., Ting, Adrian T., Iwai, Kazuhiro, Habelhah, Hasem
Published in Molecular and Cellular Biology (01.05.2013)
Published in Molecular and Cellular Biology (01.05.2013)
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TACI Isoforms Regulate Ligand Binding and Receptor Function
Garcia-Carmona, Yolanda, Ting, Adrian T, Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Published in Frontiers in immunology (02.10.2018)
Published in Frontiers in immunology (02.10.2018)
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Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORγt
Yang, Jianfei, Yang, Min, Htut, Tin Min, Ouyang, Xinshou, Hanidu, Adedayo, Li, Xiang, Sellati, Rosemarie, Jiang, Huiping, Zhang, Shu, Li, Hongxing, Zhao, Jie, Ting, Adrian T, Mayer, Lloyd, Unkeless, Jay C, Labadia, Mark E, Hodge, Martin, Li, Jun, Xiong, Huabao
Published in European journal of immunology (01.05.2008)
Published in European journal of immunology (01.05.2008)
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Journal Article
Ripoptocide - A Spark for Inflammation
Ang, Rosalind L, Chan, Mark, Ting, Adrian T
Published in Frontiers in cell and developmental biology (13.08.2019)
Published in Frontiers in cell and developmental biology (13.08.2019)
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Corrigendum: TACI Isoforms Regulate Ligand Binding and Receptor Function
Garcia-Carmona, Yolanda, Ting, Adrian T, Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Published in Frontiers in immunology (03.12.2019)
Published in Frontiers in immunology (03.12.2019)
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MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage
Klei, Linda R., Hu, Dong, Panek, Robert, Alfano, Danielle N., Bridwell, Rachel E., Bailey, Kelly M., Oravecz-Wilson, Katherine I., Concel, Vincent J., Hess, Emily M., Van Beek, Matthew, Delekta, Phillip C., Gu, Shufang, Watkins, Simon C., Ting, Adrian T., Gough, Peter J., Foley, Kevin P., Bertin, John, McAllister-Lucas, Linda M., Lucas, Peter C.
Published in Cell reports (Cambridge) (27.09.2016)
Published in Cell reports (Cambridge) (27.09.2016)
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B Cell Maturation Antigen, the Receptor for a Proliferation-Inducing Ligand and B Cell-Activating Factor of the TNF Family, Induces Antigen Presentation in B Cells
Yang, Min, Hase, Hidenori, Legarda-Addison, Diana, Varughese, Leena, Seed, Brian, Ting, Adrian T
Published in The Journal of immunology (1950) (01.09.2005)
Published in The Journal of immunology (1950) (01.09.2005)
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T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death
Chun, Nicholas, Ang, Rosalind L, Chan, Mark, Fairchild, Robert L, Baldwin, 3rd, William M, Horwitz, Julian K, Gelles, Jesse D, Chipuk, Jerry Edward, Kelliher, Michelle A, Pavlov, Vasile I, Li, Yansui, Homann, Dirk, Heeger, Peter S, Ting, Adrian T
Published in JCI insight (22.12.2021)
Published in JCI insight (22.12.2021)
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Journal Article
Caspase 8 inhibits programmed necrosis by processing CYLD
O’Donnell, Marie Anne, Perez-Jimenez, Eva, Oberst, Andrew, Ng, Aylwin, Massoumi, Ramin, Xavier, Ramnik, Green, Douglas R., Ting, Adrian T.
Published in Nature cell biology (01.12.2011)
Published in Nature cell biology (01.12.2011)
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Journal Article
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
Taft, Justin, Markson, Michael, Legarda, Diana, Patel, Roosheel, Chan, Mark, Malle, Louise, Richardson, Ashley, Gruber, Conor, Martín-Fernández, Marta, Mancini, Grazia M.S., van Laar, Jan A.M., van Pelt, Philomine, Buta, Sofija, Wokke, Beatrijs H.A., Sabli, Ira K.D., Sancho-Shimizu, Vanessa, Chavan, Pallavi Pimpale, Schnappauf, Oskar, Khubchandani, Raju, Cüceoğlu, Müşerref Kasap, Özen, Seza, Kastner, Daniel L., Ting, Adrian T., Aksentijevich, Ivona, Hollink, Iris H.I. M., Bogunovic, Dusan
Published in Cell (19.08.2021)
Published in Cell (19.08.2021)
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