Comprehensive identification of pathogenic microbes and antimicrobial resistance genes in food products using nanopore sequencing-based metagenomics
Lee, Annie Wing-Tung, Ng, Iain Chi-Fung, Wong, Evelyn Yin-Kwan, Wong, Ivan Tak-Fai, Sze, Rebecca Po-Po, Chan, Kit-Yu, So, Tsz-Yan, Zhang, Zhipeng, Ka-Yee Fung, Sharon, Choi-Ying Wong, Sally, Tam, Wing-Yin, Lao, Hiu-Yin, Lee, Lam-Kwong, Leung, Jake Siu-Lun, Chan, Chloe Toi-Mei, Ng, Timothy Ting-Leung, Zhang, Jiaying, Chow, Franklin Wang-Ngai, Leung, Polly Hang-Mei, Siu, Gilman Kit-Hang
Published in Food microbiology (01.08.2024)
Published in Food microbiology (01.08.2024)
Get full text
Journal Article
Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling
Su, Junhao, Lui, Wui Wang, Lee, YanLam, Zheng, Zhenxian, Siu, Gilman Kit-Hang, Ng, Timothy Ting-Leung, Zhang, Tong, Lam, Tommy Tsan-Yuk, Lao, Hiu-Yin, Yam, Wing-Cheong, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Lam, Tak-Wah, Leung, Amy Wing-Sze, Luo, Ruibang
Published in Scientific reports (31.03.2023)
Published in Scientific reports (31.03.2023)
Get full text
Journal Article
Clinical utility of target amplicon sequencing test for rapid diagnosis of drug-resistant Mycobacterium tuberculosis from respiratory specimens
Leung, Kenneth Siu-Sing, Tam, Kingsley King-Gee, Ng, Timothy Ting-Leung, Lao, Hiu-Yin, Shek, Raymond Chiu-Man, Ma, Oliver Chiu Kit, Yu, Shi-Hui, Chen, Jing-Xian, Han, Qi, Siu, Gilman Kit-Hang, Yam, Wing-Cheong
Published in Frontiers in microbiology (09.09.2022)
Published in Frontiers in microbiology (09.09.2022)
Get full text
Journal Article
Identification of microbial community in the urban environment: The concordance between conventional culture and nanopore 16S rRNA sequencing
Lee, Annie Wing-Tung, Chan, Chloe Toi-Mei, Wong, Lily Lok-Yee, Yip, Cheuk-Yi, Lui, Wing-Tung, Cheng, Kai-Chun, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Wong, Ivan Tak-Fai, Ng, Timothy Ting-Leung, Lao, Hiu-Yin, Siu, Gilman Kit-Hang
Published in Frontiers in microbiology (13.04.2023)
Published in Frontiers in microbiology (13.04.2023)
Get full text
Journal Article
The clinical utility of Nanopore 16S rRNA gene sequencing for direct bacterial identification in normally sterile body fluids
Lao, Hiu-Yin, Wong, Lily Lok-Yee, Hui, Yan, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Lo, Hazel Wing-Hei, Yau, Miranda Chong-Yee, Leung, Eddie Chi-Man, Wong, River Chun-Wai, Ho, Alex Yat-Man, Yip, Kam-Tong, Lam, Jimmy Yiu-Wing, Chow, Viola Chi-Ying, Luk, Kristine Shik, Que, Tak-Lun, Chow, Franklin Wang Ngai, Siu, Gilman Kit-Hang
Published in Frontiers in microbiology (09.01.2024)
Published in Frontiers in microbiology (09.01.2024)
Get full text
Journal Article
Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China
Wu, Wing-Gi, Shum, Marcus Ho-Hin, Wong, Ivan Tak-Fai, Lu, Kelvin Keru, Lee, Lam-Kwong, Leung, Jake Siu-Lun, Lao, Hiu-Yin, Lee, Annie Wing-Tung, Hau, Pak-Ting, Chan, Chloe Toi-Mei, Wong, Harmen Fung-Tin, Fung, Sharon Ka-Yee, Wong, Sally Choi-Ying, Ng, Iain Chi-Fung, Ng, Timothy Ting-Leung, Chow, Ning, Ho, Alex Yat-Man, Hung, Mei Fan, Chow, Franklin Wang-Ngai, Wong, Maureen Mo-Lin, To, Wing-Kin, Lam, Tommy Tsan-Yuk, Luk, Kristine Shik, Siu, Gilman Kit-Hang
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
Get full text
Journal Article
Genetic mechanisms of co-emergence of INH-resistant Mycobacterium tuberculosis strains during the standard course of antituberculosis therapy
Tafess, Ketema, Ng, Timothy Ting-Leung, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Lao, Hiu Yin, Chan, Chloe Toi-Mei, Yam, Wing-Cheong, Wong, Samson Sai Yin, Lau, Terrence Chi-Kwong, Siu, Gilman Kit-Hang
Published in Microbiology spectrum (02.04.2024)
Published in Microbiology spectrum (02.04.2024)
Get full text
Journal Article
Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters
Mok, Bobo Wing-Yee, Liu, Honglian, Deng, Shaofeng, Liu, Jiayan, Zhang, Anna Jinxia, Lau, Siu-Ying, Liu, Siwen, Tam, Rachel Chun-Yee, Cremin, Conor J., Ng, Timothy Ting-Leung, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Wang, Pui, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chan, Kwok-Hung, Yuen, Kwok-Yung, Siu, Gilman Kit-Hang, Chen, Honglin
Published in Communications biology (20.09.2021)
Published in Communications biology (20.09.2021)
Get full text
Journal Article
Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform
Zhu, Li, Lee, Annie Wing-Tung, Wu, Kelvin Ka-Lok, Gao, Peng, Tam, Kingsley King-Gee, Rajwani, Rahim, Chaburte, Galata Chala, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Lao, Hiu Yin, Yam, Wing Cheong, Kao, Richard Yi-Tsun, Siu, Gilman Kit Hang
Published in Antibiotics (Basel) (09.03.2022)
Published in Antibiotics (Basel) (09.03.2022)
Get full text
Journal Article
Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?
Siu, Gilman Kit-Hang, Lee, Lam-Kwong, Leung, Kenneth Siu-Sing, Leung, Jake Siu-Lun, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Tam, Kingsley King-Gee, Lao, Hiu-Yin, Wu, Alan Ka-Lun, Yau, Miranda Chong-Yee, Lai, Yvette Wai-Man, Fung, Kitty Sau-Chun, Chau, Sandy Ka-Yee, Wong, Barry Kin-Chung, To, Wing-Kin, Luk, Kristine, Ho, Alex Yat-Man, Que, Tak-Lun, Yip, Kam-Tong, Yam, Wing Cheong, Shum, David Ho-Keung, Yip, Shea Ping
Published in Emerging microbes & infections (01.01.2020)
Published in Emerging microbes & infections (01.01.2020)
Get full text
Journal Article
Targeted-Sequencing Workflows for Comprehensive Drug Resistance Profiling of Mycobacterium tuberculosis Cultures Using Two Commercial Sequencing Platforms: Comparison of Analytical and Diagnostic Performance, Turnaround Time, and Cost
Tafess, Ketema, Ng, Timothy Ting Leung, Lao, Hiu Yin, Leung, Kenneth Siu Sing, Tam, Kingsley King Gee, Rajwani, Rahim, Tam, Sarah Tsz Yan, Ho, Lily Pui Ki, Chu, Corey Mang Kiu, Gonzalez, Dimitri, Sayada, Chalom, Ma, Oliver Chiu Kit, Nega, Belete Haile, Ameni, Gobena, Yam, Wing Cheong, Siu, Gilman Kit Hang
Published in Clinical chemistry (Baltimore, Md.) (01.06.2020)
Published in Clinical chemistry (Baltimore, Md.) (01.06.2020)
Get full text
Journal Article
Long-Read Sequencing with Hierarchical Clustering for Antiretroviral Resistance Profiling of Mixed Human Immunodeficiency Virus Quasispecies
Ng, Timothy Ting-Leung, Su, Junhao, Lao, Hiu-Yin, Lui, Wui-Wang, Chan, Chloe Toi-Mei, Leung, Amy Wing-Sze, Jim, Stephanie Hoi-Ching, Lee, Lam-Kwong, Shehzad, Sheeba, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Tang, Forrest, Yam, Wing-Cheong, Luo, Ruibang, Siu, Gilman Kit-Hang
Published in Clinical chemistry (Baltimore, Md.) (03.10.2023)
Published in Clinical chemistry (Baltimore, Md.) (03.10.2023)
Get full text
Journal Article
Nanopore Sequencing Reveals Novel Targets for Detection and Surveillance of Human and Avian Influenza A Viruses
Yip, Cyril Chik-Yan, Chan, Wan-Mui, Ip, Jonathan Daniel, Seng, Claudia Win-May, Leung, Kit-Hang, Poon, Rosana Wing-Shan, Ng, Anthony Chin-Ki, Wu, Wai-Lan, Zhao, Hanjun, Chan, Kwok-Hung, Siu, Gilman Kit-Hang, Ng, Timothy Ting-Leung, Cheng, Vincent Chi-Chung, Kok, Kin-Hang, Yuen, Kwok-Yung, To, Kelvin Kai-Wang
Published in Journal of clinical microbiology (23.04.2020)
Published in Journal of clinical microbiology (23.04.2020)
Get full text
Journal Article
The Clinical Utility of Two High-Throughput 16S rRNA Gene Sequencing Workflows for Taxonomic Assignment of Unidentifiable Bacterial Pathogens in Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
Lao, Hiu-Yin, Ng, Timothy Ting-Leung, Wong, Ryan Yik-Lam, Wong, Celia Sze-Ting, Lee, Lam-Kwong, Wong, Denise Sze-Hang, Chan, Chloe Toi-Mei, Jim, Stephanie Hoi-Ching, Leung, Jake Siu-Lun, Lo, Hazel Wing-Hei, Wong, Ivan Tak-Fai, Yau, Miranda Chong-Yee, Lam, Jimmy Yiu-Wing, Wu, Alan Ka-Lun, Siu, Gilman Kit-Hang
Published in Journal of clinical microbiology (19.01.2022)
Published in Journal of clinical microbiology (19.01.2022)
Get full text
Journal Article
A low-cost TaqMan minor groove binder probe-based one-step RT-qPCR assay for rapid identification of N501Y variants of SARS-CoV-2
Chan, Chloe Toi-Mei, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Lo, Hazel Wing-Hei, Wong, Evelyn Yin-Kwan, Wong, Denise Sze-Hang, Ng, Timothy Ting-Leung, Lao, Hiu-Yin, Lu, Kelvin Keru, Jim, Stephanie Hoi-Ching, Yau, Miranda Chong-Yee, Lam, Jimmy Yiu-Wing, Ho, Alex Yat-Man, Luk, Kristine Shik, Yip, Kam-Tong, Que, Tak-Lun, To, Kelvin Kai-Wang, Siu, Gilman Kit-Hang
Published in Journal of virological methods (01.01.2022)
Published in Journal of virological methods (01.01.2022)
Get full text
Journal Article
Territorywide Study of Early Coronavirus Disease Outbreak, Hong Kong, China
Leung, Kenneth Siu-Sing, Ng, Timothy Ting-Leung, Wu, Alan Ka-Lun, Yau, Miranda Chong-Yee, Lao, Hiu-Yin, Choi, Ming-Pan, Tam, Kingsley King-Gee, Lee, Lam-Kwong, Wong, Barry Kin-Chung, Man Ho, Alex Yat, Yip, Kam-Tong, Lung, Kwok-Cheung, Liu, Raymond Wai-To, Tso, Eugene Yuk-Keung, Leung, Wai-Shing, Chan, Man-Chun, Ng, Yuk-Yung, Sin, Kit-Man, Fung, Kitty Sau-Chun, Chau, Sandy Ka-Yee, To, Wing-Kin, Que, Tak-Lun, Shum, David Ho-Keung, Yip, Shea Ping, Yam, Wing Cheong, Siu, Gilman Kit-Hang
Published in Emerging infectious diseases (01.01.2021)
Published in Emerging infectious diseases (01.01.2021)
Get full text
Journal Article
A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis
Rajwani, Rahim, Galata, Chala, Lee, Annie Wing Tung, So, Pui-Kin, Leung, Kenneth Siu Sing, Tam, Kingsley King Gee, Shehzad, Sheeba, Ng, Timothy Ting Leung, Zhu, Li, Lao, Hiu Yin, Chan, Chloe Toi-Mei, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Wong, Kin Chung, Yam, Wing Cheong, Siu, Gilman Kit-Hang
Published in Virulence (31.12.2022)
Published in Virulence (31.12.2022)
Get full text
Journal Article
The clinical utility of two high-throughput 16S rRNA gene sequencing workflows for taxonomic assignment of unidentifiable bacterial pathogens in MALDI-TOF MS
Hiu-Yin Lao, Leung Ng, Timothy Ting, Lam Wong, Ryan Yik, Celia Sze Ting Wong, Chloe Toi Mei Chan, Wong, Denise Sze Hang, Lam Kwong Lee, Stephanie Hoi Ching Jim, Jake Siu Lun Leung, Hazel Wing Hei Lo, Wong, Ivan Tak Fai, Miranda Chong Yee Yau, Lam, Jimmy Yw, Wu, Alan K L, Gilman Kit Hang Siu
Published in bioRxiv (17.08.2021)
Published in bioRxiv (17.08.2021)
Get full text
Paper
SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamsters
Bobo Wing Yee Mok, Cremin, Conor J, Siu-Ying Lau, Deng, Shaofen, Chen, Pin, Zhang, Anna Jinxia, Andrew Chak-Yiu Lee, Liu, Honglian, Liu, Siwen, Timothy Ting-Leung Ng, Hiu-Yin Lao, Eddie Lam-Kwong Lee, Kenneth Siu-Sing Leung, Wang, Pui, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung, Chan, Kwok-Yung, Yuen, Siu, Gilman Kit-Hang, Chen, Honglin
Published in bioRxiv (28.08.2020)
Published in bioRxiv (28.08.2020)
Get full text
Paper