Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients
Portnow, Jana, Synold, Timothy W, Badie, Behnam, Tirughana, Revathiswari, Lacey, Simon F, D'Apuzzo, Massimo, Metz, Marianne Z, Najbauer, Joseph, Bedell, Victoria, Vo, Tien, Gutova, Margarita, Frankel, Paul, Chen, Mike, Aboody, Karen S
Published in Clinical cancer research (15.06.2017)
Published in Clinical cancer research (15.06.2017)
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The Neuropharmacokinetics of Temozolomide in Patients with Resectable Brain Tumors: Potential Implications for the Current Approach to Chemoradiation
Portnow, Jana, Badie, Behnam, Chen, Mike, Liu, An, Blanchard, Suzette, Synold, Timothy W
Published in Clinical cancer research (15.11.2009)
Published in Clinical cancer research (15.11.2009)
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Journal Article
HIV Replication and Latency in a Humanized NSG Mouse Model during Suppressive Oral Combinational Antiretroviral Therapy
Satheesan, Sangeetha, Li, Haitang, Burnett, John C., Takahashi, Mayumi, Li, Shasha, Wu, Shiny Xiaqin, Synold, Timothy W., Rossi, John J., Zhou, Jiehua
Published in Journal of virology (01.04.2018)
Published in Journal of virology (01.04.2018)
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Journal Article
Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma
Chen, Robert, Herrera, Alex F, Hou, Jessie, Chen, Lu, Wu, Jun, Guo, Yuming, Synold, Timothy W, Ngo, Vu N, Puverel, Sandrine, Mei, Matthew, Popplewell, Leslie, Yi, Shuhua, Song, Joo Y, Tao, Shu, Wu, Xiwei, Chan, Wing C, Forman, Stephen J, Kwak, Larry W, Rosen, Steven T, Newman, Edward M
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma
Brown, Christine E, Rodriguez, Analiz, Palmer, Joycelynne, Ostberg, Julie R, Naranjo, Araceli, Wagner, Jamie R, Aguilar, Brenda, Starr, Renate, Weng, Lihong, Synold, Timothy W, Tran, Vivi, Wang, Shelley, Reik, Andreas, D’Apuzzo, Massimo, Ressler, Julie A, Zhou, Yuanyue, Mendel, Matthew, Gregory, Philip D, Holmes, Michael C, Tang, Winson W, Forman, Stephen J, Jensen, Michael C, Badie, Behnam
Published in Neuro-oncology (Charlottesville, Va.) (01.08.2022)
Published in Neuro-oncology (Charlottesville, Va.) (01.08.2022)
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Journal Article
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies
Aboody, Karen S, Najbauer, Joseph, Metz, Marianne Z, D'Apuzzo, Massimo, Gutova, Margarita, Annala, Alexander J, Synold, Timothy W, Couture, Larry A, Blanchard, Suzette, Moats, Rex A, Garcia, Elizabeth, Aramburo, Soraya, Valenzuela, Valerie V, Frank, Richard T, Barish, Michael E, Brown, Christine E, Kim, Seung U, Badie, Behnam, Portnow, Jana
Published in Science translational medicine (08.05.2013)
Published in Science translational medicine (08.05.2013)
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Journal Article
Small molecule targeting of transcription-replication conflict for selective chemotherapy
Gu, Long, Li, Min, Li, Caroline M., Haratipour, Pouya, Lingeman, Robert, Jossart, Jennifer, Gutova, Margarita, Flores, Linda, Hyde, Caitlyn, Kenjić, Nikola, Li, Haiqing, Chung, Vincent, Li, Hongzhi, Lomenick, Brett, Von Hoff, Daniel D., Synold, Timothy W., Aboody, Karen S., Liu, Yilun, Horne, David, Hickey, Robert J., Perry, J. Jefferson P., Malkas, Linda H.
Published in Cell chemical biology (19.10.2023)
Published in Cell chemical biology (19.10.2023)
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Journal Article
A phase 1 trial of 8‐chloro‐adenosine in relapsed/refractory acute myeloid leukemia: An evaluation of safety and pharmacokinetics
Pullarkat, Vinod, Chen, Lisa S., Palmer, Joycelynne, Zhang, Jianying, Synold, Timothy W., Buettner, Ralf, Truong Nguyen, Le Xuan, Marcucci, Guido, Tsai, Ni‐Chun, Wang, Yan, O’Hearn, James, Gandhi, Varsha, Rosen, Steven T.
Published in Cancer (01.03.2024)
Published in Cancer (01.03.2024)
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Journal Article
Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double-blind, placebo-controlled, randomised, phase 3 trial
Ryan, Christopher W, Tangen, Catherine M, Heath, Elisabeth I, Stein, Mark N, Meng, Maxwell V, Alva, Ajjai S, Pal, Sumanta K, Puzanov, Igor, Clark, Joseph I, Choueiri, Toni K, Agarwal, Neeraj, Uzzo, Robert G, Haas, Naomi B, Synold, Timothy W, Plets, Melissa, Vaishampayan, Ulka N, Shuch, Brian M, Thompson, Ian M, Lara, Primo N
Published in The Lancet (British edition) (23.09.2023)
Published in The Lancet (British edition) (23.09.2023)
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Cell facilitation promotes growth and survival under drug pressure in breast cancer
Emond, Rena, Griffiths, Jason I., Grolmusz, Vince Kornél, Nath, Aritro, Chen, Jinfeng, Medina, Eric F., Sousa, Rachel S., Synold, Timothy, Adler, Frederick R., Bild, Andrea H.
Published in Nature communications (29.06.2023)
Published in Nature communications (29.06.2023)
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A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
BINGSEN ZHOU, LEILA SU, HORNE, David, YUN YEN, SHUYA HU, WEIDONG HU, YIP, M. L. Richard, JUN WU, GAUR, Shikha, LYNNE SMITH, D, YUAN, Yate-Ching, SYNOLD, Timothy W
Published in Cancer research (Chicago, Ill.) (01.11.2013)
Published in Cancer research (Chicago, Ill.) (01.11.2013)
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Journal Article
Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis
Parise, Robert A., Covey, Joseph M., Hollingshead, Melinda G., Srivastava, Apurva K., Synold, Timothy W., Beumer, Jan H.
Published in Journal of pharmaceutical and biomedical analysis (05.09.2021)
Published in Journal of pharmaceutical and biomedical analysis (05.09.2021)
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Journal Article
The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA
Gu, Long, Lingeman, Robert, Yakushijin, Fumiko, Sun, Emily, Cui, Qi, Chao, Jianfei, Hu, Weidong, Li, Hongzhi, Hickey, Robert J, Stark, Jeremy M, Yuan, Yate-Ching, Chen, Yuan, Vonderfecht, Steven L, Synold, Timothy W, Shi, Yanhong, Reckamp, Karen L, Horne, David, Malkas, Linda H
Published in Clinical cancer research (01.12.2018)
Published in Clinical cancer research (01.12.2018)
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Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts
Doroshow, James H., Gaur, Shikha, Markel, Susan, Lu, Jiamo, van Balgooy, Josephus, Synold, Timothy W., Xi, Bixin, Wu, Xiwei, Juhasz, Agnes
Published in Free radical biology & medicine (01.04.2013)
Published in Free radical biology & medicine (01.04.2013)
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Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, BDE-100, and BDE-153) in Human Breast Cancer Cells and Patient-Derived Xenografts
Kanaya, Noriko, Bernal, Lauren, Chang, Gregory, Yamamoto, Takuro, Nguyen, Duc, Wang, Yuan-Zhong, Park, June-Soo, Warden, Charles, Wang, Jinhui, Wu, Xiwei, Synold, Timothy, Rakoff, Michele, Neuhausen, Susan L, Chen, Shiuan
Published in Toxicological sciences (01.06.2019)
Published in Toxicological sciences (01.06.2019)
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First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies
Weiss, Glen J., Chao, Joseph, Neidhart, Jeffrey D., Ramanathan, Ramesh K., Bassett, Dawn, Neidhart, James A., Choi, Chung Hang J., Chow, Warren, Chung, Vincent, Forman, Stephen J., Garmey, Edward, Hwang, Jungyeon, Kalinoski, D. Lynn, Koczywas, Marianna, Longmate, Jeffrey, Melton, Roger J., Morgan, Robert, Oliver, Jamie, Peterkin, Joanna J., Ryan, John L., Schluep, Thomas, Synold, Timothy W., Twardowski, Przemyslaw, Davis, Mark E., Yen, Yun
Published in Investigational new drugs (01.08.2013)
Published in Investigational new drugs (01.08.2013)
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Adjuvant Everolimus in Patients with Completely Resected, Very High-risk Renal Cell Carcinoma of Clear Cell Histology: Results from the Phase 3 Placebo-controlled SWOG S0931 (EVEREST) Trial
Lara, Primo N., Tangen, Catherine, Heath, Elisabeth I., Gulati, Shuchi, Stein, Mark N., Meng, Maxwell, Alva, Ajjai Shivaram, Pal, Sumanta K., Puzanov, Igor, Clark, Joseph I., Choueiri, Toni K., Agarwal, Neeraj, Uzzo, Robert, Haas, Naomi B., Synold, Timothy W., Plets, Melissa, Vaishampayan, Ulka N., Shuch, Brian M., Lerner, Seth, Thompson, Ian M., Ryan, Christopher W.
Published in European urology (01.09.2024)
Published in European urology (01.09.2024)
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