p53 partial loss-of-function mutations sensitize to chemotherapy
Klimovich, Boris, Merle, Nastasja, Neumann, Michelle, Elmshäuser, Sabrina, Nist, Andrea, Mernberger, Marco, Kazdal, Daniel, Stenzinger, Albrecht, Timofeev, Oleg, Stiewe, Thorsten
Published in Oncogene (11.02.2022)
Published in Oncogene (11.02.2022)
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Journal Article
mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability
Gremke, Niklas, Polo, Pierfrancesco, Dort, Aaron, Schneikert, Jean, Elmshäuser, Sabrina, Brehm, Corinna, Klingmüller, Ursula, Schmitt, Anna, Reinhardt, Hans Christian, Timofeev, Oleg, Wanzel, Michael, Stiewe, Thorsten
Published in Nature communications (17.09.2020)
Published in Nature communications (17.09.2020)
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Journal Article
Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo
Klimovich, Boris, Stiewe, Thorsten, Timofeev, Oleg
Published in Cell cycle (Georgetown, Tex.) (02.01.2020)
Published in Cell cycle (Georgetown, Tex.) (02.01.2020)
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Journal Article
Drainage of high-consistency fiber-laden aqueous foams
Koponen, Antti I., Timofeev, Oleg, Jäsberg, Ari, Kiiskinen, Harri
Published in Cellulose (London) (01.11.2020)
Published in Cellulose (London) (01.11.2020)
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Journal Article
Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways
Shreeram, Sathyavageeswaran, Demidov, Oleg N., Hee, Weng Kee, Yamaguchi, Hiroshi, Onishi, Nobuyuki, Kek, Calvina, Timofeev, Oleg N., Dudgeon, Crissy, Fornace, Albert J., Anderson, Carl W., Minami, Yasuhiro, Appella, Ettore, Bulavin, Dmitry V.
Published in Molecular cell (01.09.2006)
Published in Molecular cell (01.09.2006)
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Journal Article
ERK pathway agonism for cancer therapy: evidence, insights, and a target discovery framework
Timofeev, Oleg, Giron, Philippe, Lawo, Steffen, Pichler, Martin, Noeparast, Maxim
Published in NPJ precision oncology (14.03.2024)
Published in NPJ precision oncology (14.03.2024)
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Journal Article
Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5
Vogiatzi, Fotini, Brandt, Dominique T., Schneikert, Jean, Fuchs, Jeannette, Grikscheit, Katharina, Wanzel, Michael, Pavlakis, Evangelos, Charles, Joël P., Timofeev, Oleg, Nist, Andrea, Mernberger, Marco, Kantelhardt, Eva J., Siebolts, Udo, Bartel, Frank, Jacob, Ralf, Rath, Ariane, Moll, Roland, Grosse, Robert, Stiewe, Thorsten
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2016)
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Journal Article
Influence of SHS Precursor Composition on the Properties of Yttria Powders and Optical Ceramics
Permin, Dmitry, Postnikova, Olga, Balabanov, Stanislav, Belyaev, Alexander, Koshkin, Vitaliy, Timofeev, Oleg, Li, Jiang
Published in Materials (27.12.2022)
Published in Materials (27.12.2022)
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Journal Article
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses
Timofeev, Oleg, Klimovich, Boris, Schneikert, Jean, Wanzel, Michael, Pavlakis, Evangelos, Noll, Julia, Mutlu, Samet, Elmshäuser, Sabrina, Nist, Andrea, Mernberger, Marco, Lamp, Boris, Wenig, Ulrich, Brobeil, Alexander, Gattenlöhner, Stefan, Köhler, Kernt, Stiewe, Thorsten
Published in The EMBO journal (15.10.2019)
Published in The EMBO journal (15.10.2019)
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Journal Article
Partial p53 reactivation is sufficient to induce cancer regression
Klimovich, Boris, Meyer, Laura, Merle, Nastasja, Neumann, Michelle, König, Alexander M, Ananikidis, Nikolaos, Keber, Corinna U, Elmshäuser, Sabrina, Timofeev, Oleg, Stiewe, Thorsten
Published in Journal of experimental & clinical cancer research (02.03.2022)
Published in Journal of experimental & clinical cancer research (02.03.2022)
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Journal Article
p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo
Timofeev, Oleg, Schlereth, Katharina, Wanzel, Michael, Braun, Attila, Nieswandt, Bernhard, Pagenstecher, Axel, Rosenwald, Andreas, Elsässer, Hans-Peter, Stiewe, Thorsten
Published in Cell reports (Cambridge) (30.05.2013)
Published in Cell reports (Cambridge) (30.05.2013)
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Journal Article
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase
Merle, Nastasja, Elmshäuser, Sabrina, Strassheimer, Florian, Wanzel, Michael, König, Alexander M, Funk, Julianne, Neumann, Michelle, Kochhan, Katharina, Helmprobst, Frederik, Pagenstecher, Axel, Nist, Andrea, Mernberger, Marco, Schneider, André, Braun, Thomas, Borggrefe, Tilman, Savai, Rajkumar, Timofeev, Oleg, Stiewe, Thorsten
Published in Molecular cancer (03.10.2022)
Published in Molecular cancer (03.10.2022)
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Journal Article
Drying of Pigment-Cellulose Nanofibril Substrates
Timofeev, Oleg, Torvinen, Katariina, Sievänen, Jenni, Kaljunen, Timo, Kouko, Jarmo, Ketoja, Jukka A
Published in Materials (01.10.2014)
Published in Materials (01.10.2014)
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Journal Article
Enhancing oncogenic signaling to kill cancer cells
Noeparast, Maxim, Timofeev, Oleg, Pichler, Martin
Published in Trends in pharmacological sciences (Regular ed.) (01.06.2024)
Published in Trends in pharmacological sciences (Regular ed.) (01.06.2024)
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Journal Article
A Subtle Change in p38 MAPK Activity is Sufficient to Suppress In Vivo Tumorigenesis
Timofeev, Oleg, Lee, Ting Yi, Bulavin, Dmitry V
Published in Cell cycle (Georgetown, Tex.) (01.01.2005)
Published in Cell cycle (Georgetown, Tex.) (01.01.2005)
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Journal Article
Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy
Klimovich, Boris, Mutlu, Samet, Schneikert, Jean, Elmshäuser, Sabrina, Klimovich, Maria, Nist, Andrea, Mernberger, Marco, Timofeev, Oleg, Stiewe, Thorsten
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2019)
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Journal Article