Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition
Holt, Amy K, Najumudeen, Arafath K, Collard, Tracey J, Li, Hao, Millett, Laura M, Hoskin, Ashley J, Legge, Danny N, Mortensson, Eleanor M H, Flanagan, Dustin J, Jones, Nicholas, Kollareddy, Madhu, Timms, Penny, Hitchings, Matthew D, Cronin, James, Sansom, Owen J, Williams, Ann C, Vincent, Emma E
Published in Cancer & metabolism (19.10.2023)
Published in Cancer & metabolism (19.10.2023)
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Journal Article
The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer: implications for the treatment of colorectal carcinogenesis
Legge, Danny N, Chambers, Adam C, Parker, Christopher T, Timms, Penny, Collard, Tracey J, Williams, Ann C
Published in Carcinogenesis (New York) (14.05.2020)
Published in Carcinogenesis (New York) (14.05.2020)
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Journal Article
BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination
Parker, Christopher, Chambers, Adam C., Flanagan, Dustin J., Ho, Jasmine Wing Yu, Collard, Tracey J., Ngo, Greg, Baird, Duncan M., Timms, Penny, Morgan, Rhys G., Sansom, Owen J., Williams, Ann C.
Published in DNA repair (01.07.2022)
Published in DNA repair (01.07.2022)
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Journal Article
The Cass Review into medical care provided to children with gender dysphoria has been released. Here’s what it found: There's been a mixed response amongst Australian medical professionals after the release of England's Cass Review into the treatment of children with gender dysphoria. Here's what some of them had to say about the findings
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Newsletter
Some Australians are taking the gamble to self-fund their private healthcare but experts warn it's not for everyone: As private health premiums are set to rise, some Australians are making a conscious decision to opt for "self-insurance" rather than "health insurance" to cut down on expenses. Experts warn it's not for everyone
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Taskforce Magnus blitz on organised crime prevents at least two murders in past five weeks, NSW Police say: Nine people, including two women, were arrested overnight over a range of gun and drug offences, with prohibited items and cash seized, following an operation by Taskforce Magnus
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Support for going sober in the bush as new program helps break the stigma of giving up alcohol: Sober In The Country has now blossomed into a social impact enterprise and peer support network called the Bush Tribe, helping people in Australia's regions break the alcohol cycle
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Chefs, doctors and real estate developers among new coalition calling to rid kitchens of gas cooking: For decades, "natural gas" has sold itself to families as the fastest and most efficient way to cook. But now there's a battle for your kitchen stove, and a push to get you to embrace electric
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Great Barrier Reef coral cover at record levels after mass-bleaching events, report shows: Record coral cover is being seen across much of the Great Barrier Reef as it recovers from past storms and mass bleaching events. But the new coral taking over is leaving the reef more vulnerable to future devastating impacts, according to the Australian Institute of Marine Science (AIMS)
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Climate change has made old measures predicting weather events in Australia 'essentially worthless': Around Australia, statistical measures like the "one-in-100-year flood" level are used by authorities to determine safe building standards, but experts say climate change has changed everything
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Government infighting over climate change made giving honest policy advice harder, tribunal told: Internal conflict within the Morrison government on climate change policy made it harder for public servants to give frank advice about how to prepare for worsening climate extremes, according to the sworn testimony of a senior bureaucrat
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Children's climate change case overturned on appeal as Federal Court dismisses government's 'duty of care': Federal Environment Minister Sussan Ley successfully argues she does not have a duty of care to protect young people from climate change when assessing fossil fuel projects
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COVID rapid antigen tests can return false negatives, but experts say they're accurate when it counts the most: Rapid antigen tests are more likely to return false negatives than PCR tests, but experts say they are useful for identifying when a person is at their most infectious. So how can they be used in Australia?
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Pharmacists welcome COVID-19 vaccine funding increase, but say more needs to be done to stop burnout: Pharmacists are calling for funding equity between them and general practitioners who administer COVID-19 vaccinations, to help avoid workforce burnout and ensure Australia's immunisation schedule stays on track
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JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells
Lawson, Hannah, Sepulveda, Catarina, van de Lagemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter, O'Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P., Göttgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O'Carroll, Dónal, Kranc, Kamil R.
Published in Blood advances (09.02.2021)
Published in Blood advances (09.02.2021)
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Journal Article