Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes
Dodd, Michael S., PhD, Sousa Fialho, Maria da Luz, MSc, Montes Aparicio, Claudia N., MSc, Kerr, Matthew, MSc, Timm, Kerstin N., PhD, Griffin, Julian L., PhD, Luiken, Joost J.F.P., PhD, Glatz, Jan F.C., PhD, Tyler, Damian J., PhD, Heather, Lisa C., PhD
Published in JACC. Basic to translational science (01.08.2018)
Published in JACC. Basic to translational science (01.08.2018)
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Journal Article
Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse
Marco-Rius, Irene, Tayler, Michael C. D., Kettunen, Mikko I., Larkin, Timothy J., Timm, Kerstin N., Serrao, Eva M., Rodrigues, Tiago B., Pileio, Giuseppe, Ardenkjaer-Larsen, Jan Henrik, Levitt, Malcolm H., Brindle, Kevin M.
Published in NMR in biomedicine (01.12.2013)
Published in NMR in biomedicine (01.12.2013)
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Journal Article
Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol
Kerr, Matthew, Miller, Jack J, Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N, Aparicio, Claudia N Montes, Scott, Iain, Tyler, Damian J, Heather, Lisa C
Published in JCI insight (03.09.2020)
Published in JCI insight (03.09.2020)
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Journal Article
L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI
Savic, Dragana, Ball, Vicky, Curtis, M Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N, Hauton, David, West, James, Griffin, Julian, Heather, Lisa C, Tyler, Damian J
Published in Metabolites (23.03.2021)
Published in Metabolites (23.03.2021)
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Journal Article
Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy
Timm, Kerstin N., Hu, De-En, Williams, Michael, Wright, Alan J., Kettunen, Mikko I., Kennedy, Brett W.C., Larkin, Timothy J., Dzien, Piotr, Marco-Rius, Irene, Bohndiek, Sarah E., Brindle, Kevin M.
Published in The Journal of biological chemistry (03.02.2017)
Published in The Journal of biological chemistry (03.02.2017)
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Journal Article
AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats
Choksey, Anurag, Carter, Ryan D., Thackray, Benjamin D., Ball, Vicky, Kennedy, Brett W.C., Ha, Lea Hong Tuan, Sharma, Eshita, Broxholme, John, Castro-Guarda, Marcos, Murphy, Michael P., Heather, Lisa C., Tyler, Damian J., Timm, Kerstin N.
Published in Journal of molecular and cellular cardiology (01.06.2024)
Published in Journal of molecular and cellular cardiology (01.06.2024)
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Journal Article
Hyperpolarized magnetic resonance shows that the anti‐ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post‐ischemic function in the diabetic heart
Savic, Dragana, Ball, Vicky, Holzner, Lorenz, Hauton, David, Timm, Kerstin N., Curtis, M. Kate, Heather, Lisa C., Tyler, Damian J.
Published in NMR in biomedicine (01.04.2021)
Published in NMR in biomedicine (01.04.2021)
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Journal Article
A 3D hybrid‐shot spiral sequence for hyperpolarized 13C imaging
Tyler, Andrew, Lau, Justin Y. C., Ball, Vicky, Timm, Kerstin N., Zhou, Tony, Tyler, Damian J., Miller, Jack J.
Published in Magnetic resonance in medicine (01.02.2021)
Published in Magnetic resonance in medicine (01.02.2021)
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Journal Article
Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response
Timm, Kerstin N, Kennedy, Brett W C, Brindle, Kevin M
Published in Clinical cancer research (01.11.2016)
Published in Clinical cancer research (01.11.2016)
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Journal Article
Rapid, B1‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux
Miller, Jack J., Valkovič, Ladislav, Kerr, Matthew, Timm, Kerstin N., Watson, William D., Lau, Justin Y. C., Tyler, Andrew, Rodgers, Christopher, Bottomley, Paul A., Heather, Lisa C., Tyler, Damian J.
Published in Magnetic resonance in medicine (01.06.2021)
Published in Magnetic resonance in medicine (01.06.2021)
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Journal Article
Cardiac applications of hyperpolarised magnetic resonance
Timm, Kerstin N., Miller, Jack J., Henry, John A., Tyler, Damian J.
Published in Progress in nuclear magnetic resonance spectroscopy (01.06.2018)
Published in Progress in nuclear magnetic resonance spectroscopy (01.06.2018)
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Journal Article
Nicotinic acid receptor agonists impair myocardial contractility by energy starvation
Watson, William D., Timm, Kerstin N., Lewis, Andrew J., Miller, Jack J. J., Emmanuel, Yaso, Clarke, Kieran, Neubauer, Stefan, Tyler, Damian J., Rider, Oliver J.
Published in The FASEB journal (01.11.2020)
Published in The FASEB journal (01.11.2020)
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Journal Article
Hyperpolarized [U-2H, U-13C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells
Timm, Kerstin N., Hartl, Johannes, Keller, Markus A., Hu, De-En, Kettunen, Mikko I., Rodrigues, Tiago B., Ralser, Markus, Brindle, Kevin M.
Published in Magnetic resonance in medicine (01.12.2015)
Published in Magnetic resonance in medicine (01.12.2015)
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Journal Article
Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR
Marco-Rius, Irene, Wright, Alan J., Hu, De-en, Savic, Dragana, Miller, Jack J., Timm, Kerstin N., Tyler, Damian, Brindle, Kevin M., Comment, Arnaud
Published in Magma (New York, N.Y.) (01.02.2021)
Published in Magma (New York, N.Y.) (01.02.2021)
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Journal Article
(13) C magnetic resonance spectroscopic imaging of hyperpolarized [1-(13) C, U-(2) H5 ] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo
Dzien, Piotr, Kettunen, Mikko I, Marco-Rius, Irene, Serrao, Eva M, Rodrigues, Tiago B, Larkin, Timothy J, Timm, Kerstin N, Brindle, Kevin M
Published in Magnetic resonance in medicine (01.05.2015)
Published in Magnetic resonance in medicine (01.05.2015)
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Journal Article
Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
Timm, Kerstin N., Apps, Andrew, Miller, Jack J., Ball, Vicky, Chong, Cher‐Rin, Dodd, Michael S., Tyler, Damian J.
Published in NMR in biomedicine (01.09.2018)
Published in NMR in biomedicine (01.09.2018)
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Journal Article
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI
Timm, Kerstin N, Perera, Charith, Ball, Vicky, Henry, John A, Miller, Jack J, Kerr, Matthew, West, James A, Sharma, Eshita, Broxholme, John, Logan, Angela, Savic, Dragana, Dodd, Michael S, Griffin, Julian L, Murphy, Michael P, Heather, Lisa C, Tyler, Damian J
Published in Communications biology (19.11.2020)
Published in Communications biology (19.11.2020)
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