Treatment of Highly Drug-Resistant Pulmonary Tuberculosis
Conradie, Francesca, Diacon, Andreas H, Ngubane, Nosipho, Howell, Pauline, Everitt, Daniel, Crook, Angela M, Mendel, Carl M, Egizi, Erica, Moreira, Joanna, Timm, Juliano, McHugh, Timothy D, Wills, Genevieve H, Bateson, Anna, Hunt, Robert, Van Niekerk, Christo, Li, Mengchun, Olugbosi, Morounfolu, Spigelman, Melvin
Published in The New England journal of medicine (05.03.2020)
Published in The New England journal of medicine (05.03.2020)
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Journal Article
Bedaquiline–Pretomanid–Linezolid Regimens for Drug-Resistant Tuberculosis
Conradie, Francesca, Bagdasaryan, Tatevik R., Borisov, Sergey, Howell, Pauline, Mikiashvili, Lali, Ngubane, Nosipho, Samoilova, Anastasia, Skornykova, Sergey, Tudor, Elena, Variava, Ebrahim, Yablonskiy, Petr, Everitt, Daniel, Wills, Genevieve H., Sun, Eugene, Olugbosi, Morounfolu, Egizi, Erica, Li, Mengchun, Holsta, Alda, Timm, Juliano, Bateson, Anna, Crook, Angela M., Fabiane, Stella M., Hunt, Robert, McHugh, Timothy D., Tweed, Conor D., Foraida, Salah, Mendel, Carl M., Spigelman, Melvin
Published in The New England journal of medicine (01.09.2022)
Published in The New England journal of medicine (01.09.2022)
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Journal Article
Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre, partially randomised controlled trial
Cevik, Muge, Thompson, Lindsay C, Upton, Caryn, Rolla, Valéria Cavalcanti, Malahleha, Mookho, Mmbaga, Blandina, Ngubane, Nosipho, Abu Bakar, Zamzurina, Rassool, Mohammed, Variava, Ebrahim, Dawson, Rodney, Staples, Suzanne, Lalloo, Umesh, Louw, Cheryl, Conradie, Francesca, Eristavi, Marika, Samoilova, Anastasia, Skornyakov, Sergey N, Ntinginya, Niyanda Elias, Haraka, Frederick, Praygod, George, Mayanja-Kizza, Harriett, Caoili, Janice, Balanag, Vincent, Dalcolmo, Margareth Pretti, McHugh, Timothy, Hunt, Robert, Solanki, Priya, Bateson, Anna, Crook, Angela M, Fabiane, Stella, Timm, Juliano, Sun, Eugene, Spigelman, Melvin, Sloan, Derek J, Gillespie, Stephen H, Bruinenberg, Paul, Beumont, Maria, Nedelman, Jerry, Li, Mengchun, Zuma-Gwala, Ntokozo, Rajaram, Shakira, Choo, Louise, Wills, Genevive, Betteridge, Matt, Leandra, Leandra, Olugbosi, Morounfolu, Borisov, Sergey
Published in The Lancet infectious diseases (01.09.2024)
Published in The Lancet infectious diseases (01.09.2024)
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Journal Article
PA-459 The effect on treatment outcomes of baseline resistance to pyrazinamide after 6-months of BPaMZ in the SimpliciTB clinical trial
Timm, Juliano, McHugh, Timothy, Crook, Angela, Nedelman, Jerry, Olugbosi, Morounfolu, Gillespie, Stephen H, Beumont, Maria, Sun, Eugene
Published in BMJ global health (17.12.2023)
Published in BMJ global health (17.12.2023)
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Journal Article
Prevalence and genetic basis of Mycobacterium tuberculosis resistance to pretomanid in China
Zhao, Bing, Zheng, Huiwen, Timm, Juliano, Song, Zexuan, Pei, Shaojun, Xing, Ruida, Guo, Yajie, Ma, Ling, Li, Feina, Li, Qing, Li, Yan, Huang, Lin, Teng, Chong, Wang, Ni, Gupta, Aastha, Juneja, Sandeep, Huang, Fei, Zhao, Yanlin, Ou, Xichao
Published in Annals of clinical microbiology and antimicrobials (03.05.2024)
Published in Annals of clinical microbiology and antimicrobials (03.05.2024)
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Journal Article
Baseline and acquired resistance to bedaquiline, linezolid and pretomanid, and impact on treatment outcomes in four tuberculosis clinical trials containing pretomanid
Timm, Juliano, Bateson, Anna, Solanki, Priya, Paleckyte, Ana, Witney, Adam A., Rofael, Sylvia A. D., Fabiane, Stella, Olugbosi, Morounfolu, McHugh, Timothy D., Sun, Eugene
Published in PLOS global public health (18.10.2023)
Published in PLOS global public health (18.10.2023)
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Journal Article
Differential Expression of Iron-, Carbon-, and Oxygen-Responsive Mycobacterial Genes in the Lungs of Chronically Infected Mice and Tuberculosis Patients
Timm, Juliano, Post, Frank A., Bekker, Linda-Gail, Walther, Gabriele B., Wainwright, Helen C., Manganelli, Riccardo, Chan, Wai-Tsing, Tsenova, Liana, Gold, Benjamin, Smith, Issar, Kaplan, Gilla, McKinney, John D.
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
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Journal Article
Ribonucleotide Reduction in Mycobacterium tuberculosis: Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases
DAWES, Stephanie S, WARNER, Digby F, TSENOVA, Liana, TIMM, Juliano, MCKINNEY, John D, KAPLAN, Gilla, RUBIN, Harvey, MIZRAHI, Valerie
Published in Infection and Immunity (01.11.2003)
Published in Infection and Immunity (01.11.2003)
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Journal Article
Regimens for Drug-Resistant Tuberculosis. Reply
Timm, Juliano, Crook, Angela M, Sun, Eugene
Published in The New England journal of medicine (12.01.2023)
Published in The New England journal of medicine (12.01.2023)
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Journal Article
A Multidrug-Resistant, acr1-Deficient Clinical Isolate of Mycobacterium tuberculosis Is Unimpaired for Replication in Macrophages
Timm, Juliano, Kurepina, Natalia, Kreiswirth, Barry N., Post, Frank A., Walther, Gabrielle B., Wainwright, Helen C., Bekker, Linda-Gail, Kaplan, Gilla, McKinney, John D.
Published in The Journal of infectious diseases (15.06.2006)
Published in The Journal of infectious diseases (15.06.2006)
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Journal Article
Combating antimicrobial resistance in malaria, HIV and tuberculosis
Duffey, Maëlle, Shafer, Robert W., Timm, Juliano, Burrows, Jeremy N., Fotouhi, Nader, Cockett, Mark, Leroy, Didier
Published in Nature reviews. Drug discovery (01.06.2024)
Published in Nature reviews. Drug discovery (01.06.2024)
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Journal Article
Transposition of an antibiotic resistance element in mycobacteria
Martin, Carlos, Timm, Juliano, Rauzier, Jean, Gomez-Lus, Rafael, Davies, Julian, Gicquel, Brigitte
Published in Nature (London) (21.06.1990)
Published in Nature (London) (21.06.1990)
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Journal Article
Regimens for Drug-Resistant Tuberculosis
Perumal, Rubeshan, Nimmo, Camus, O’Donnell, Max, Lange, Christoph, Köhler, Niklas, Günther, Gunar, Timm, Juliano, Crook, Angela M., Sun, Eugene
Published in The New England journal of medicine (12.01.2023)
Published in The New England journal of medicine (12.01.2023)
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Journal Article
MIC of Delamanid (OPC-67683) against Mycobacterium tuberculosis Clinical Isolates and a Proposed Critical Concentration
Stinson, Kelly, Kurepina, Natalia, Venter, Amour, Fujiwara, Mamoru, Kawasaki, Masanori, Timm, Juliano, Shashkina, Elena, Kreiswirth, Barry N, Liu, Yongge, Matsumoto, Makoto, Geiter, Lawrence
Published in Antimicrobial agents and chemotherapy (01.06.2016)
Published in Antimicrobial agents and chemotherapy (01.06.2016)
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Journal Article
Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid
Bateson, Anna, Ortiz Canseco, Julio, McHugh, Timothy D., Witney, Adam A., Feuerriegel, Silke, Merker, Matthias, Kohl, Thomas A., Utpatel, Christian, Niemann, Stefan, Andres, Sönke, Kranzer, Katharina, Maurer, Florian P, Ghodousi, Arash, Borroni, Emanuele, Cirillo, Daniela Maria, Wijkander, Maria, Toro, Juan C., Groenheit, Ramona, Werngren, Jim, Machado, Diana, Viveiros, Miguel, Warren, Robin M., Sirgel, Frederick, Dippenaar, Anzaan, Köser, Claudio U., Sun, Eugene, Timm, Juliano
Published in Journal of antimicrobial chemotherapy (29.05.2022)
Published in Journal of antimicrobial chemotherapy (29.05.2022)
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Journal Article
Bedaquiline, pretomanid and linezolid for treatment of extensively drug resistant, intolerant or non-responsive multidrug resistant pulmonary tuberculosis
Conradie, Francesca, Diacon, Andreas H, Ngubane, Nosipho, Howell, Pauline, Everitt, Daniel, Crook, Angela M, Mendel, Carl M, Egizi, Erica, Moreira, Joanna, Timm, Juliano, McHugh, Timothy D, Wills, Genevieve, Bateson, Anna, Hunt, Robert, Van Niekerk, Christo, Li, Mengchun, Olugbosi, Morounfolu, Spigelman, Melvin
Published in The New England journal of medicine (05.03.2020)
Published in The New England journal of medicine (05.03.2020)
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Journal Article
Purification and properties of the Mycobacterium smegmatis mc2155 β-lactamase
Quinting, Birgit, Galleni, Moreno, Timm, Juliano, Gicquel, Brigitte, Amicosante, Gianfranco, Frère, Jean-Marie
Published in FEMS microbiology letters (01.04.1997)
Published in FEMS microbiology letters (01.04.1997)
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Journal Article
Bedaquiline, pretomanid and linezolid for treatment of extensively drug resistant, intolerant or non-responsive multidrug resistant pulmonary tuberculosis
Conradie, Francesca, Diacon, Andreas H, Ngubane, Nosipho, Howell, Pauline, Everitt, Daniel, Crook, Angela M, Mendel, Carl M, Egizi, Erica, Moreira, Joanna, Timm, Juliano, McHugh, Timothy D, Wills, Genevieve, Bateson, Anna, Hunt, Robert, Van Niekerk, Christo, Li, Mengchun, Olugbosi, Morounfolu, Spigelman, Melvin
Published in The New England journal of medicine (05.03.2020)
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Published in The New England journal of medicine (05.03.2020)
Journal Article
Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR
Dussurget, O, Timm, J, Gomez, M, Gold, B, Yu, S, Sabol, S Z, Holmes, R K, Jacobs, Jr, W R, Smith, I
Published in Journal of bacteriology (01.06.1999)
Published in Journal of bacteriology (01.06.1999)
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Journal Article