A Review of the Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Vedolizumab
Rosario, Maria, Dirks, Nathanael L., Milch, Catherine, Parikh, Asit, Bargfrede, Michael, Wyant, Tim, Fedyk, Eric, Fox, Irving
Published in Clinical pharmacokinetics (01.11.2017)
Published in Clinical pharmacokinetics (01.11.2017)
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Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
Feagan, Brian G, Rutgeerts, Paul, Sands, Bruce E, Hanauer, Stephen, Colombel, Jean-Frédéric, Sandborn, William J, Van Assche, Gert, Axler, Jeffrey, Kim, Hyo-Jong, Danese, Silvio, Fox, Irving, Milch, Catherine, Sankoh, Serap, Wyant, Tim, Xu, Jing, Parikh, Asit
Published in The New England journal of medicine (22.08.2013)
Published in The New England journal of medicine (22.08.2013)
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Vedolizumab for the treatment of active ulcerative colitis: A randomized controlled phase 2 dose‐ranging study
Parikh, Asit, Leach, Timothy, Wyant, Tim, Scholz, Catherine, Sankoh, Serap, Mould, Diane R., Ponich, Terry, Fox, Irving, Feagan, Brian G.
Published in Inflammatory bowel diseases (01.08.2012)
Published in Inflammatory bowel diseases (01.08.2012)
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Effect of CC Chemokine Receptor 2 CCR2 Blockade on Serum C-Reactive Protein in Individuals at Atherosclerotic Risk and With a Single Nucleotide Polymorphism of the Monocyte Chemoattractant Protein-1 Promoter Region
Gilbert, Jim, MD, Lekstrom-Himes, Julie, MD, Donaldson, Debra, MD, Lee, Yih, PhD, Hu, Mingxiu, PhD, Xu, Jing, PhD, Wyant, Tim, MD, Davidson, Michael, MD
Published in The American journal of cardiology (15.03.2011)
Published in The American journal of cardiology (15.03.2011)
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A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo
Gallery, Melissa, Zhang, Julie, Bradley, Daniel P, Brauer, Pamela, Cvet, Donna, Estevam, Jose, Danaee, Hadi, Greenfield, Edward, Li, Ping, Manfredi, Mark, Loke, Huay-Keng, Rabino, Claudia, Stringer, Brad, Williamson, Mark, Wyant, Tim, Yang, Johnny, Zhu, Qing, Abu-Yousif, Adnan, Veiby, O Petter
Published in PloS one (01.01.2018)
Published in PloS one (01.01.2018)
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Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis
Lebre, Maria C, Vergunst, Clarissa E, Choi, Ivy Y K, Aarrass, Saïda, Oliveira, Ana S F, Wyant, Tim, Horuk, Richard, Reedquist, Kris A, Tak, Paul P
Published in PloS one (01.07.2011)
Published in PloS one (01.07.2011)
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Vedolizumab affects antibody responses to immunisation selectively in the gastrointestinal tract: randomised controlled trial results
Wyant, Tim, Leach, Tim, Sankoh, Serap, Wang, Yuemei, Paolino, Jonathan, Pasetti, Marcela F, Feagan, Brian G, Parikh, Asit
Published in Gut (01.01.2015)
Published in Gut (01.01.2015)
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Vedolizumab, a monoclonal antibody to the gut homing α4β7 integrin, does not affect cerebrospinal fluid T-lymphocyte immunophenotype
Milch, Catherine, Wyant, Tim, Xu, Jing, Parikh, Asit, Kent, Whitney, Fox, Irving, Berger, Joseph
Published in Journal of neuroimmunology (15.11.2013)
Published in Journal of neuroimmunology (15.11.2013)
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Exclusive antagonism of the α4β7 integrin by vedolizumab confirms the gut‐selectivity of this pathway in primates
Fedyk, Eric R., Wyant, Tim, Yang, Li‐Li, Csizmadia, Vilmos, Burke, Kristine, Yang, Hua, Kadambi, Vivek J.
Published in Inflammatory bowel diseases (01.11.2012)
Published in Inflammatory bowel diseases (01.11.2012)
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Trial in progress: A phase 1-2, first-in-human, open label, dose escalation and expansion study of AU-007, a monoclonal antibody that binds to IL-2 and inhibits IL-2Rα binding, in patients with advanced solid tumors
Vasselli, James Robert, Frentzas, Sophia, Weickhardt, Andrew James, de Souza, Paul L., Tang, Jenny, Wyant, Tim, Amit, Inbar, Ofran, Yanay, Knickerbocker, Aron
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Fecal Calprotectin Responses Following Induction Therapy With Vedolizumab in Moderate to Severe Ulcerative Colitis: A Post Hoc Analysis of GEMINI 1
Reinisch, Walter, Bressler, Brian, Curtis, Rebecca, Parikh, Asit, Yang, Huyuan, Rosario, Maria, Røseth, Arne, Danese, Silvio, Feagan, Brian, Sands, Bruce E, Ginsburg, Philip, Dassopoulos, Themistocles, Lewis, James, Xu, Jing, Wyant, Tim
Published in Inflammatory bowel diseases (14.03.2019)
Published in Inflammatory bowel diseases (14.03.2019)
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Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody-Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies
Almhanna, Khaldoun, Kalebic, Thea, Cruz, Cristina, Faris, Jason E, Ryan, David P, Jung, JungAh, Wyant, Tim, Fasanmade, Adedigbo A, Messersmith, Wells, Rodon, Jordi
Published in Clinical cancer research (15.10.2016)
Published in Clinical cancer research (15.10.2016)
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Antagonizing the α4β1 integrin, but not α4β7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis
Haanstra, Krista G, Hofman, Sam O, Lopes Estêvão, Dave M, Blezer, Erwin L A, Bauer, Jan, Yang, Li-Li, Wyant, Tim, Csizmadia, Vilmos, 't Hart, Bert A, Fedyk, Eric R
Published in The Journal of immunology (1950) (01.03.2013)
Published in The Journal of immunology (1950) (01.03.2013)
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Phase I Study of the Investigational Anti-Guanylyl Cyclase AntibodyDrug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies
Almhanna, Khaldoun, Kalebic, Thea, Cruz, Cristina, Faris, Jason E, Ryan, David P, Jung, JungAh, Wyant, Tim, Fasanmade, Adedigbo A, Messersmith, Wells, Rodon, Jordi
Published in Clinical cancer research (15.10.2016)
Published in Clinical cancer research (15.10.2016)
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Vedolizumab Does Not Affect the Suppressive Activity of Gut-homing T Regulatory Cells: P-177
Fedyk, Eric, Yang, Li-Li, Wyant, Tim, Kadambi, Vivek
Published in Inflammatory bowel diseases (01.12.2012)
Published in Inflammatory bowel diseases (01.12.2012)
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