Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody
McLellan, Jason S., Chen, Man, Leung, Sherman, Graepel, Kevin W., Du, Xiulian, Yang, Yongping, Zhou, Tongqing, Baxa, Ulrich, Yasuda, Etsuko, Beaumont, Tim, Kumar, Azad, Modjarrad, Kayvon, Zheng, Zizheng, Zhao, Min, Xia, Ningshao, Kwong, Peter D., Graham, Barney S.
Published in Science (American Association for the Advancement of Science) (31.05.2013)
Published in Science (American Association for the Advancement of Science) (31.05.2013)
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Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
McLellan, Jason S., Chen, Man, Joyce, M. Gordon, Sastry, Mallika, Stewart-Jones, Guillaume B. E., Yang, Yongping, Zhang, Baoshan, Chen, Lei, Srivatsan, Sanjay, Zheng, Anqi, Zhou, Tongqing, Graepel, Kevin W., Kumar, Azad, Moin, Syed, Boyington, Jeffrey C., Chuang, Gwo-Yu, Soto, Cinque, Baxa, Ulrich, Bakker, Arjen Q., Spits, Hergen, Beaumont, Tim, Zheng, Zizheng, Xia, Ningshao, Ko, Sung-Youl, Todd, John-Paul, Rao, Srinivas, Graham, Barney S., Kwong, Peter D.
Published in Science (American Association for the Advancement of Science) (01.11.2013)
Published in Science (American Association for the Advancement of Science) (01.11.2013)
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Resistance to ABT-199 induced by microenvironmental signals in chronic lymphocytic leukemia can be counteracted by CD20 antibodies or kinase inhibitors
Thijssen, Rachel, Slinger, Erik, Weller, Katinka, Geest, Christian R, Beaumont, Tim, van Oers, Marinus H J, Kater, Arnon P, Eldering, Eric
Published in Haematologica (Roma) (01.08.2015)
Published in Haematologica (Roma) (01.08.2015)
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A panel of hepatitis C virus glycoproteins for the characterization of antibody responses using antibodies with diverse recognition and neutralization patterns
Chumbe, Ana, Grobben, Marloes, Capella-Pujol, Joan, Koekkoek, Sylvie M., Zon, Ian, Slamanig, Stefan, Merat, Sabrina J., Beaumont, Tim, Sliepen, Kwinten, Schinkel, Janke, van Gils, Marit J.
Published in Virus research (01.03.2024)
Published in Virus research (01.03.2024)
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Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein
Gilman, Morgan S A, Moin, Syed M, Mas, Vicente, Chen, Man, Patel, Nita K, Kramer, Kari, Zhu, Qing, Kabeche, Stephanie C, Kumar, Azad, Palomo, Concepción, Beaumont, Tim, Baxa, Ulrich, Ulbrandt, Nancy D, Melero, José A, Graham, Barney S, McLellan, Jason S
Published in PLoS pathogens (01.07.2015)
Published in PLoS pathogens (01.07.2015)
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common solution to group 2 influenza virus neutralization
Friesen, Robert H. E., Lee, Peter S., Stoop, Esther J. M., Hoffman, Ryan M. B., Ekiert, Damian C., Bhabha, Gira, Yu, Wenli, Juraszek, Jarek, Koudstaal, Wouter, Jongeneelen, Mandy, Korse, Hans J. W. M., Ophorst, Carla, Brinkman-van der Linden, Els C. M., Throsby, Mark, Kwakkenbos, Mark J., Bakker, Arjen Q., Beaumont, Tim, Spits, Hergen, Kwaks, Ted, Vogels, Ronald, Ward, Andrew B., Goudsmit, Jaap, Wilson, Ian A.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
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Primary SARS-CoV-2 variant of concern infections elicit broad antibody Fc-mediated effector functions and memory B cell responses
van der Straten, Karlijn, Guerra, Denise, Kerster, Gius, Claireaux, Mathieu, Grobben, Marloes, Schriek, Angela I, Boyd, Anders, van Rijswijk, Jacqueline, Tejjani, Khadija, Eggink, Dirk, Beaumont, Tim, de Taeye, Steven W, de Bree, Godelieve J, Sanders, Rogier W, van Gils, Marit J
Published in PLoS pathogens (15.08.2024)
Published in PLoS pathogens (15.08.2024)
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Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming
Scheeren, Ferenc A, van Bleek, Grada M, Spits, Hergen, Radbruch, Andreas, van Geelen, Caroline M M, Bakker, Arjen Q, Yasuda, Etsuko, Beaumont, Tim, Widjojoatmodjo, Myra N, Diehl, Sean A, Kwakkenbos, Mark J, Bogers, Willy M J M, Mei, Henrik, Lukens, Michaël V
Published in Nature medicine (01.01.2010)
Published in Nature medicine (01.01.2010)
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Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
Brouwer, Philip J.M., Perrett, Hailee R., Beaumont, Tim, Nijhuis, Haye, Kruijer, Sabine, Burger, Judith A., Bontjer, Ilja, Lee, Wen-Hsin, Ferguson, James A., Schauflinger, Martin, Müller-Kräuter, Helena, Sanders, Rogier W., Strecker, Thomas, van Gils, Marit J., Ward, Andrew B.
Published in Cell reports (Cambridge) (24.09.2024)
Published in Cell reports (Cambridge) (24.09.2024)
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Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity
Wagner, Koen, Kwakkenbos, Mark J., Claassen, Yvonne B., Maijoor, Kelly, Böhne, Martino, van der Sluijs, Koenraad F., Witte, Martin D., van Zoelen, Diana J., Cornelissen, Lisette A., Beaumont, Tim, Bakker, Arjen Q., Ploegh, Hidde L., Spits, Hergen, Garcia, K. Christopher
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
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Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis
Shakeel, Shabih, Westerhuis, Brenda M., Domanska, Ausra, Koning, Roman I., Matadeen, Rishi, Koster, Abraham J., Bakker, Arjen Q., Beaumont, Tim, Wolthers, Katja C., Butcher, Sarah J.
Published in Nature communications (20.07.2016)
Published in Nature communications (20.07.2016)
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Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain
Guerra, Denise, Radić, Laura, Brinkkemper, Mitch, Poniman, Meliawati, van der Maas, Lara, Torres, Jonathan L, Ward, Andrew B, Sliepen, Kwinten, Schinkel, Janke, Sanders, Rogier W, van Gils, Marit J, Beaumont, Tim
Published in Human vaccines & immunotherapeutics (31.12.2024)
Published in Human vaccines & immunotherapeutics (31.12.2024)
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Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies
Shakeel, Shabih, Westerhuis, Brenda M, Ora, Ari, Koen, Gerrit, Bakker, Arjen Q, Claassen, Yvonne, Wagner, Koen, Beaumont, Tim, Wolthers, Katja C, Butcher, Sarah J
Published in Journal of virology (01.09.2015)
Published in Journal of virology (01.09.2015)
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Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance
Merat, Sabrina J, Molenkamp, Richard, Wagner, Koen, Koekkoek, Sylvie M, van de Berg, Dorien, Yasuda, Etsuko, Böhne, Martino, Claassen, Yvonne B, Grady, Bart P, Prins, Maria, Bakker, Arjen Q, de Jong, Menno D, Spits, Hergen, Schinkel, Janke, Beaumont, Tim
Published in PloS one (24.10.2016)
Published in PloS one (24.10.2016)
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Tipping the Noxa/Mcl-1 Balance Overcomes ABT-737 Resistance in Chronic Lymphocytic Leukemia
TROMP, Jacqueline M, GEEST, Christian R, BREIJ, Esther C. W, ELIAS, Judith A, LAAR, Jacoline Van, LUIJKS, Dieuwertje M, KATER, Arnon P, BEAUMONT, Tim, OERS, Marinus H. J. Van, ELDERING, Eric
Published in Clinical cancer research (15.01.2012)
Published in Clinical cancer research (15.01.2012)
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Strain-dependent neutralization reveals antigenic variation of human parechovirus 3
Karelehto, Eveliina, van der Sanden, Sabine, Geraets, James A., Domanska, Aušra, van der Linden, Lonneke, Hoogendoorn, Dionne, Koen, Gerrit, van Eijk, Hetty, Shakeel, Shabih, Beaumont, Tim, de Jong, Menno, Pajkrt, Dasja, Butcher, Sarah J., Wolthers, Katja C.
Published in Scientific reports (21.09.2017)
Published in Scientific reports (21.09.2017)
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Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins
Hazenbos, Wouter L W, Kajihara, Kimberly K, Vandlen, Richard, Morisaki, J Hiroshi, Lehar, Sophie M, Kwakkenbos, Mark J, Beaumont, Tim, Bakker, Arjen Q, Phung, Qui, Swem, Lee R, Ramakrishnan, Satish, Kim, Janice, Xu, Min, Shah, Ishita M, Diep, Binh An, Sai, Tao, Sebrell, Andrew, Khalfin, Yana, Oh, Angela, Koth, Chris, Lin, S Jack, Lee, Byoung-Chul, Strandh, Magnus, Koefoed, Klaus, Andersen, Peter S, Spits, Hergen, Brown, Eric J, Tan, Man-Wah, Mariathasan, Sanjeev
Published in PLoS pathogens (01.10.2013)
Published in PLoS pathogens (01.10.2013)
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Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice
Becker, Pablo D, Legrand, Nicolas, van Geelen, Caroline M M, Noerder, Miriam, Huntington, Nicholas D, Lim, Annick, Yasuda, Etsuko, Diehl, Sean A, Scheeren, Ferenc A, Ott, Michael, Weijer, Kees, Wedemeyer, Heiner, Di Santo, James P, Beaumont, Tim, Guzman, Carlos A, Spits, Hergen
Published in PloS one (04.10.2010)
Published in PloS one (04.10.2010)
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Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual
Guerra, Denise, Beaumont, Tim, Radić, Laura, Kerster, Gius, van der Straten, Karlijn, Yuan, Meng, Torres, Jonathan L., Lee, Wen-Hsin, Liu, Hejun, Poniman, Meliawati, Bontjer, Ilja, Burger, Judith A., Claireaux, Mathieu, Caniels, Tom G., Snitselaar, Jonne L., Bijl, Tom P.L., Kruijer, Sabine, Ozorowski, Gabriel, Gideonse, David, Sliepen, Kwinten, Ward, Andrew B., Eggink, Dirk, de Bree, Godelieve J., Wilson, Ian A., Sanders, Rogier W., van Gils, Marit J.
Published in iScience (20.10.2023)
Published in iScience (20.10.2023)
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