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An open-label, randomized, controlled, multicenter study exploring two treatment strategies of rivaroxaban and a dose-adjusted oral vitamin k antagonist treatment strategy in subjects with atrial fibrillation who undergo percutaneous coronary intervention (PIONEER AF-PCI)
Gibson, C. Michael, Mehran, Roxana, Bode, Christoph, Halperin, Johnathan, Verheugt, Freek, Wildgoose, Peter, van Eickels, Martin, Lip, Gregory Y.H., Cohen, Marc, Husted, Steen, Peterson, Eric, Fox, Keith
Published in The American heart journal (01.04.2015)
Published in The American heart journal (01.04.2015)
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Bedside Monitoring to Adjust Antiplatelet Therapy for Coronary Stenting
Collet, Jean-Philippe, Cuisset, Thomas, Rangé, Grégoire, Cayla, Guillaume, Elhadad, Simon, Pouillot, Christophe, Henry, Patrick, Motreff, Pascal, Carrié, Didier, Boueri, Ziad, Belle, Loic, Van Belle, Eric, Rousseau, Hélène, Aubry, Pierre, Monségu, Jacques, Sabouret, Pierre, O'Connor, Stephen A, Abtan, Jérémie, Kerneis, Mathieu, Saint-Etienne, Christophe, Barthélémy, Olivier, Beygui, Farzin, Silvain, Johanne, Vicaut, Eric, Montalescot, Gilles
Published in The New England journal of medicine (29.11.2012)
Published in The New England journal of medicine (29.11.2012)
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Dosing Clopidogrel Based on CYP2C19 Genotype and the Effect on Platelet Reactivity in Patients With Stable Cardiovascular Disease
Mega, Jessica L, Hochholzer, Willibald, Frelinger, Andrew L, Kluk, Michael J, Angiolillo, Dominick J, Kereiakes, Dean J, Isserman, Steven, Rogers, William J, Ruff, Christian T, Contant, Charles, Pencina, Michael J, Scirica, Benjamin M, Longtine, Janina A, Michelson, Alan D, Sabatine, Marc S
Published in JAMA : the journal of the American Medical Association (23.11.2011)
Published in JAMA : the journal of the American Medical Association (23.11.2011)
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Lesion Complexity and Outcomes of Extended Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
Yeh, Robert W., Kereiakes, Dean J., Steg, P. Gabriel, Cutlip, Donald E., Croce, Kevin J., Massaro, Joseph M., Mauri, Laura
Published in Journal of the American College of Cardiology (31.10.2017)
Published in Journal of the American College of Cardiology (31.10.2017)
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Morphine Decreases Clopidogrel Concentrations and Effects: A Randomized, Double-Blind, Placebo-Controlled Trial
HOBL, Eva-Luise, STIMPFL, Thomas, EBNER, Josef, SCHOERGENHOFER, Christian, DERHASCHNIG, Ulla, SUNDER-PLASSMANN, Raute, JILMA-STOHLAWETZ, Petra, MANNHALTER, Christine, POSCH, Martin, JILMA, Bernd
Published in Journal of the American College of Cardiology (25.02.2014)
Published in Journal of the American College of Cardiology (25.02.2014)
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Greater Clinical Benefit of More Intensive Oral Antiplatelet Therapy With Prasugrel in Patients With Diabetes Mellitus in the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38
Wiviott, Stephen D., Braunwald, Eugene, Angiolillo, Dominick J., Meisel, Simha, Dalby, Anthony J., Verheugt, Freek W.A., Goodman, Shaun G., Corbalan, Ramon, Purdy, Drew A., Murphy, Sabina A., McCabe, Carolyn H., Antman, Elliott M.
Published in Circulation (New York, N.Y.) (14.10.2008)
Published in Circulation (New York, N.Y.) (14.10.2008)
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Bleeding After Initiation of Multiple Antithrombotic Drugs, Including Triple Therapy, in Atrial Fibrillation Patients Following Myocardial Infarction and Coronary Intervention: A Nationwide Cohort Study
Lamberts, Morten, Olesen, Jonas Bjerring, Ruwald, Martin Huth, Hansen, Carolina Malta, Karasoy, Deniz, Kristensen, Søren Lund, Køber, Lars, Torp-Pedersen, Christian, Gislason, Gunnar Hilmar, Hansen, Morten Lock
Published in Circulation (New York, N.Y.) (04.09.2012)
Published in Circulation (New York, N.Y.) (04.09.2012)
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Impact of Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention: Insights From the CHAMPION PHOENIX Trial (Clinical Trial Comparing Cangrelor to Clopidogrel Standard of Care Therapy in Subjects Who Require Percutaneous Coronary Intervention)
GENEREUX, Philippe, STONE, Gregg W, TIEPU LIU, TODD, Meredith, SKERJANEC, Simona, HAMM, Christian W, MAHAFFEY, Kenneth W, WHITE, Harvey D, BHATT, Deepak L, HARRINGTON, Robert A, GIBSON, C. Michael, STEG, Ph. gabriel, BRENER, Sorin J, ANGIOLILLO, Dominick J, PRICE, Matthew J, PRATS, Jayne, LASALLE, Laura
Published in Journal of the American College of Cardiology (25.02.2014)
Published in Journal of the American College of Cardiology (25.02.2014)
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Prasugrel Compared With High Loading- and Maintenance-Dose Clopidogrel in Patients With Planned Percutaneous Coronary Intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation–Thrombolysis in Myocardial Infarction 44 Trial
Wiviott, Stephen D., Trenk, Dietmar, Frelinger, Andrew L., O’Donoghue, Michelle, Neumann, Franz-Josef, Michelson, Alan D., Angiolillo, Dominick J., Hod, Hanoch, Montalescot, Gilles, Miller, Debra L., Jakubowski, Joseph A., Cairns, Richard, Murphy, Sabina A., McCabe, Carolyn H., Antman, Elliott M., Braunwald, Eugene
Published in Circulation (New York, N.Y.) (18.12.2007)
Published in Circulation (New York, N.Y.) (18.12.2007)
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Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function
Frelinger, Andrew L., Bhatt, Deepak L., Lee, Ronald D., Mulford, Darcy J., Wu, Jingtao, Nudurupati, Sai, Nigam, Anu, Lampa, Michael, Brooks, Julie K., Barnard, Marc R., Michelson, Alan D.
Published in Journal of the American College of Cardiology (26.02.2013)
Published in Journal of the American College of Cardiology (26.02.2013)
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Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation
Nakamura, Masato, Iijima, Raisuke, Ako, Junya, Shinke, Toshiro, Okada, Hisayuki, Ito, Yoshiaki, Ando, Kenji, Tanaka, Hiroyuki, Takiuchi, Shin, Nishida, Yasunori, Kawaguchi, Katsuhiro, Kadotani, Makoto, Omiya, Kazuto, Morita, Takashi, Yasaka, Yoshinori, Ishiwata, Sugao, Ochiai, Masahiko, Yokoi, Hiroyoshi, Okada, Hisayuki, Ito, Yoshiaki, Hara, Hidehiko, Ando, Kenji, Ueda, Yasunori, Takiuchi, Shin, Nishida, Yasunori, Kawaguchi, Katsuhiro, Kadotani, Makoto, Niinuma, Hiroyuki, Omiya, Kazuto, Morita, Takashi, Zen, Kan, Yaita, Yoshinori, Inoue, Kenji, Ishiwata, Sugao, Ochiai, Masahiko, Takamisawa, Itaru, Ishihara, Takayuki, Ashida, Kazuhiro, Kongoji, Ken, Shiode, Nobuo, Mukawa, Hiroaki, Komiyama, Kota, Suzuki, Takeshi, Ueno, Takafumi, Yamashita, Jun, Kamiya, Haruo, Fujita, Hiroshi, Ajioka, Masayoshi, Mizuno, Koichi, Hirayama, Haruo, Tojo, Taiki, Kawasaki, Tomohiro, Toyota, Fumitoshi, Michishita, Ichiro, Kamihata, Hiroshi, Ishizaka, Nobukazu, Ashikaga, Takashi, Ozaki, Yukio, Hara, Hisao, Doi, Naofumi, Yokoi, Hiroyoshi, Takano, Hitoshi, Ozawa, Toru, Kikuchi, Arifumi, Kadota, Kazushige, Kijima, Yoichi, Shimada, Yoshihisa, Yumoto, Kazuhiko, Kawajiri, Kenji, Nozaki, Yoichi, Tosaka, Atsushi, Hirose, Mizuki, Takagi, Yuichiro, Takagi, Takuro, Miyauchi, Katsumi, Misu, Kazuhiko, Yasuda, Satoshi, Inoue, Ichiro, Yoshiyama, Minoru, Masuyama, Toru, Tomobuchi, Yoshiaki, Tanabe, Kengo, Wagatsuma, Kenji, Kato, Masayuki, Kawai, Kazuya, Shibata, Yoshisato, Tachibana, Koichi, Yoshioka, Jiro, Mori, Chikara, Kataoka, Toru, Terai, Hidenobu, Onishi, Yuko, Toma, Masanao, Serikawa, Takeshi, Yano, Shoji, Ebisawa, Soichiro, Takashima, Hiroaki, Shimomura, Hideki, Kurumatani, Yoko, Sonoda, Shinjo
Published in JACC. Cardiovascular interventions (26.06.2017)
Published in JACC. Cardiovascular interventions (26.06.2017)
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Mortality Benefit With Prasugrel in the TRITON―TIMI 38 Coronary Artery Bypass Grafting Cohort: Risk-Adjusted Retrospective Data Analysis
SMITH, Peter K, GOODNOUGH, Lawrence T, LEVY, Jerrold H, POSTON, Robert S, SHORT, Mary A, WEERAKKODY, Govinda J, LENARZ, Leroy A
Published in Journal of the American College of Cardiology (31.07.2012)
Published in Journal of the American College of Cardiology (31.07.2012)
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Precision and Reliability of 5 Platelet Function Tests in Healthy Volunteers and Donors on Daily Antiplatelet Agent Therapy
Karon, Brad S, Tolan, Nicole V, Koch, Christopher D, Wockenfus, Amy M, Miller, Randall S, Lingineni, Ravi K, Pruthi, Rajiv K, Chen, Dong, Jaffe, Allan S
Published in Clinical chemistry (Baltimore, Md.) (01.12.2014)
Published in Clinical chemistry (Baltimore, Md.) (01.12.2014)
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A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation
Brandt, John T., Payne, Christopher D., Wiviott, Stephen D., Weerakkody, Govinda, Farid, Nagy A., Small, David S., Jakubowski, Joseph A., Naganuma, Hideo, Winters, Kenneth J.
Published in The American heart journal (2007)
Published in The American heart journal (2007)
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Relation of Cytochrome P450 2C19 Loss-of-Function Polymorphism to Occurrence of Drug-Eluting Coronary Stent Thrombosis
Giusti, Betti, Gori, Anna Maria, Marcucci, Rossella, Saracini, Claudia, Sestini, Ilaria, Paniccia, Rita, Buonamici, Piergiovanni, Antoniucci, David, Abbate, Rosanna, Gensini, Gian Franco
Published in The American journal of cardiology (15.03.2009)
Published in The American journal of cardiology (15.03.2009)
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Genetic polymorphisms and the impact of a higher clopidogrel dose regimen on active metabolite exposure and antiplatelet response in healthy subjects
Simon, T, Bhatt, D L, Bergougnan, L, Farenc, C, Pearson, K, Perrin, L, Vicaut, E, Lacreta, F, Hurbin, F, Dubar, M
Published in Clinical pharmacology and therapeutics (01.08.2011)
Published in Clinical pharmacology and therapeutics (01.08.2011)
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Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
Jernberg, Tomas, Payne, Christopher D., Winters, Kenneth J., Darstein, Christelle, Brandt, John T., Jakubowski, Joseph A., Naganuma, Hideo, Siegbahn, Agneta, Wallentin, Lars
Published in European heart journal (01.05.2006)
Published in European heart journal (01.05.2006)
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Increased Platelet Inhibition After Switching From Maintenance Clopidogrel to Prasugrel in Patients With Acute Coronary Syndromes: Results of the SWAP (Switching Anti Platelet) Study
ANGIOLILLO, Dominick J, SAUCEDO, Jorge F, DERAAD, Roger, FRELINGER, Andrew L, GURBEL, Paul A, COSTIGAN, Timothy M, JAKUBOWSKI, Joseph A, OJEH, Clement K, EFFRON, Mark B
Published in Journal of the American College of Cardiology (21.09.2010)
Published in Journal of the American College of Cardiology (21.09.2010)
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Reversal of the anti‐platelet effects of aspirin and clopidogrel
LI, C., HIRSH, J., XIE, C., JOHNSTON, M. A., EIKELBOOM, J. W.
Published in Journal of thrombosis and haemostasis (01.04.2012)
Published in Journal of thrombosis and haemostasis (01.04.2012)
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