Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
Tichet, Mélanie, Wullschleger, Stephan, Chryplewicz, Agnieszka, Fournier, Nadine, Marcone, Rachel, Kauzlaric, Annamaria, Homicsko, Krisztian, Deak, Laura Codarri, Umaña, Pablo, Klein, Christian, Hanahan, Douglas
Published in Immunity (Cambridge, Mass.) (10.01.2023)
Published in Immunity (Cambridge, Mass.) (10.01.2023)
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Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies
Didier, Robin, Mallavialle, Aude, Ben Jouira, Rania, Domdom, Marie Angela, Tichet, Mélanie, Auberger, Patrick, Luciano, Frédéric, Ohanna, Mickael, Tartare-Deckert, Sophie, Deckert, Marcel
Published in Molecular cancer therapeutics (01.07.2018)
Published in Molecular cancer therapeutics (01.07.2018)
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The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion
Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K, Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Published in PloS one (20.07.2012)
Published in PloS one (20.07.2012)
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Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
Zeng, Qiqun, Saghafinia, Sadegh, Chryplewicz, Agnieszka, Fournier, Nadine, Christe, Lucine, Xie, Yu-Qing, Guillot, Jeremy, Yucel, Simge, Li, Pumin, Galván, José A., Karamitopoulou, Eva, Zlobec, Inti, Ataca, Dalya, Gallean, Fleuriane, Zhang, Peng, Rodriguez-Calero, José Antonio, Rubin, Mark, Tichet, Mélanie, Homicsko, Krisztian, Hanahan, Douglas
Published in Science (American Association for the Advancement of Science) (18.11.2022)
Published in Science (American Association for the Advancement of Science) (18.11.2022)
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Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis
Tichet, Mélanie, Prod’Homme, Virginie, Fenouille, Nina, Ambrosetti, Damien, Mallavialle, Aude, Cerezo, Michael, Ohanna, Mickaël, Audebert, Stéphane, Rocchi, Stéphane, Giacchero, Damien, Boukari, Fériel, Allegra, Maryline, Chambard, Jean-Claude, Lacour, Jean-Philippe, Michiels, Jean-François, Borg, Jean-Paul, Deckert, Marcel, Tartare-Deckert, Sophie
Published in Nature communications (30.04.2015)
Published in Nature communications (30.04.2015)
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Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner
Cerezo, Michaël, Tichet, Mélanie, Abbe, Patricia, Ohanna, Mickaël, Lehraiki, Abdelali, Rouaud, Florian, Allegra, Maryline, Giacchero, Damien, Bahadoran, Philippe, Bertolotto, Corine, Tartare-Deckert, Sophie, Ballotti, Robert, Rocchi, Stéphane
Published in Molecular cancer therapeutics (01.08.2013)
Published in Molecular cancer therapeutics (01.08.2013)
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Journal Article
SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness
Crottès, David, Rapetti-Mauss, Raphael, Alcaraz-Perez, Francisca, Tichet, Mélanie, Gariano, Giuseppina, Martial, Sonia, Guizouarn, Hélène, Pellissier, Bernard, Loubat, Agnès, Popa, Alexandra, Paquet, Agnès, Presta, Marco, Tartare-Deckert, Sophie, Cayuela, Maria Luisa, Martin, Patrick, Borgese, Franck, Soriani, Olivier
Published in Cancer research (Chicago, Ill.) (01.02.2016)
Published in Cancer research (Chicago, Ill.) (01.02.2016)
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Journal Article
Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV + Cancers
Galliverti, Gabriele, Wullschleger, Stephan, Tichet, Mélanie, Murugan, Dhaarini, Zangger, Nadine, Horton, Wesley, Korman, Alan J, Coussens, Lisa M, Swartz, Melody A, Hanahan, Douglas
Published in Cancer immunology research (01.01.2020)
Published in Cancer immunology research (01.01.2020)
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The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression
Fenouille, Nina, Robert, Guillaume, Tichet, Mélanie, Puissant, Alexandre, Dufies, Maeva, Rocchi, Stéphane, Ortonne, Jean-Paul, Deckert, Marcel, Ballotti, Robert, Tartare-Deckert, Sophie
Published in Pigment cell and melanoma research (01.02.2011)
Published in Pigment cell and melanoma research (01.02.2011)
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Journal Article
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
Chryplewicz, Agnieszka, Scotton, Julie, Tichet, Mélanie, Zomer, Anoek, Shchors, Ksenya, Joyce, Johanna A., Homicsko, Krisztian, Hanahan, Douglas
Published in Cancer cell (10.10.2022)
Published in Cancer cell (10.10.2022)
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Journal Article
Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness
Puissant, Alexandre, Dufies, Maeva, Fenouille, Nina, Ben Sahra, Issam, Jacquel, Arnaud, Robert, Guillaume, Cluzeau, Thomas, Deckert, Marcel, Tichet, Mélanie, Chéli, Yann, Cassuto, Jill-Patrice, Raynaud, Sophie, Legros, Laurence, Pasquet, Jean-Max, Mahon, François-Xavier, Luciano, Frédéric, Auberger, Patrick
Published in Journal of molecular cell biology (01.08.2012)
Published in Journal of molecular cell biology (01.08.2012)
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Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction
Brémond, Aurore, Meynet, Ophélie, Mahiddine, Karim, Coito, Sylvie, Tichet, Mélanie, Scotlandi, Katia, Breittmayer, Jean-Philippe, Gounon, Pierre, Gleeson, Paul A., Bernard, Alain, Bernard, Ghislaine
Published in Blood (08.01.2009)
Published in Blood (08.01.2009)
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ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis
Michael, Iacovos P., Saghafinia, Sadegh, Tichet, Mélanie, Zangger, Nadine, Marinoni, Ilaria, Perren, Aurel, Hanahan, Douglas
Published in Developmental cell (06.05.2019)
Published in Developmental cell (06.05.2019)
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Journal Article
Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice
Galliverti, Gabriele, Tichet, Mélanie, Domingos-Pereira, Sonia, Hauert, Sylvie, Nardelli-Haefliger, Denise, Swartz, Melody A, Hanahan, Douglas, Wullschleger, Stephan
Published in Cancer immunology research (01.11.2018)
Published in Cancer immunology research (01.11.2018)
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Risk for nevus transformation and melanoma proliferation and invasion during natalizumab treatment: four years of dermoscopic follow-up with immunohistological studies and proliferation and invasion assays
Pharaon, Momen, Tichet, Mélanie, Lebrun-Frénay, Christine, Tartare-Deckert, Sophie, Passeron, Thierry
Published in JAMA dermatology (Chicago, Ill.) (01.08.2014)
Published in JAMA dermatology (Chicago, Ill.) (01.08.2014)
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Abstract 71: The immunocytokine PD1-IL2v overcomes immune checkpoint resistance, and combination with an anti-PD-L1 antibody further enhances its anti-tumor activity
Wullschleger, Stephan, Tichet, Mélanie, Codarri-Deak, Laura, Umana, Pablo, Klein, Christian, Hanahan, Douglas
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
The Epithelial-Mesenchymal Transition Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion
Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K, Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Published in PloS one (20.07.2012)
Published in PloS one (20.07.2012)
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Journal Article
The Epithelial-Mesenchymal Transition
Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K, Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Published in PloS one (20.07.2012)
Published in PloS one (20.07.2012)
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Journal Article
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
Codarri Deak, Laura, Nicolini, Valeria, Hashimoto, Masao, Karagianni, Maria, Schwalie, Petra C., Lauener, Laura, Varypataki, Eleni Maria, Richard, Marine, Bommer, Esther, Sam, Johannes, Joller, Stefanie, Perro, Mario, Cremasco, Floriana, Kunz, Leo, Yanguez, Emilio, Hüsser, Tamara, Schlenker, Ramona, Mariani, Marisa, Tosevski, Vinko, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Colombetti, Sara, Gueripel, Xavier, Wullschleger, Stephan, Tichet, Melanie, Hanahan, Douglas, Kissick, Haydn T., Leclair, Stephane, Freimoser-Grundschober, Anne, Seeber, Stefan, Teichgräber, Volker, Ahmed, Rafi, Klein, Christian, Umaña, Pablo
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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The p53/p21 Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression
Fenouille, Nina, Robert, Guillaume, Tichet, Mélanie, Puissant, Alexandre, Dufies, Maeva, Rocchi, Stéphane, Ortonne, Jean‐Paul, Deckert, Marcel, Ballotti, Robert, Tartare‐Deckert, Sophie
Published in Pigment cell and melanoma research (01.02.2011)
Published in Pigment cell and melanoma research (01.02.2011)
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