Bruton's tyrosine kinase as a new therapeutic target
Uckun, Fatih M, Tibbles, Heather E, Vassilev, Alexei O
Published in Anti-cancer agents in medicinal chemistry (01.11.2007)
Published in Anti-cancer agents in medicinal chemistry (01.11.2007)
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Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia
GOODMAN, Patricia A, BURKHARDT, Nicole, JURAN, Brian, TIBBLES, Heather E, UCKUN, Faith M
Published in Oncogene (24.04.2003)
Published in Oncogene (24.04.2003)
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Journal Article
Role of a JAK3-dependent Biochemical Signaling Pathway in Platelet Activation and Aggregation
Tibbles, Heather E., Vassilev, Alexei, Wendorf, Heather, Schonhoff, Dawn, Zhu, Dan, Lorenz, David, Waurzyniak, Barbara, Liu, Xing-Ping, Uckun, Fatih M.
Published in The Journal of biological chemistry (25.05.2001)
Published in The Journal of biological chemistry (25.05.2001)
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Thrombopoietin Induces P-Selectin Expression on Platelets and Subsequent Platelet/Leukocyte Interactions
Tibbles, Heather E., Navara, Christopher S., Hupke, Michael A., Vassilev, Alexei O., Uckun, Fatih M.
Published in Biochemical and biophysical research communications (12.04.2002)
Published in Biochemical and biophysical research communications (12.04.2002)
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Targeting JAK3 and BTK tyrosine kinases with rationally-designed inhibitors
Vassilev, Alexei O, Tibbles, Heather E, DuMez, Darin, Venkatachalam, Taracad K, Uckun, Fatih M
Published in Current drug targets (01.03.2006)
Published in Current drug targets (01.03.2006)
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The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism
Uckun, Fatih M, Vassilev, Alexei, Bartell, Steve, Zheng, Yaguo, Mahajan, Sandeep, Tibbles, Heather E
Published in Leukemia & lymphoma (01.09.2003)
Published in Leukemia & lymphoma (01.09.2003)
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Journal Article
SYK and LYN Mediate B-cell Receptor-independent Calcium-induced Apoptosis in DT-40 Lymphoma B-cells
Zhu, De-Min, Tibbles, Heather E., Vassilev, Alexei O., Uckun, Fatih M.
Published in Leukemia & lymphoma (01.11.2002)
Published in Leukemia & lymphoma (01.11.2002)
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Journal Article
Effect of targeting janus kinase 3 on the development of intestinal tumors in the adenomatous polyposis coli(min) mouse model of familial adenomatous polyposis
Uckun, Fatih M, Erbeck, Douglas, Qazi, Sanjive, Venkatachalam, Taracad, Tibbles, Heather E, Vassilev, Alexei
Published in Arzneimittel-Forschung (2007)
Published in Arzneimittel-Forschung (2007)
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In vivo pharmacokinetics, metabolism, toxicity, and anti-HIV activity of N'-[2-(2-Thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a potent non-nucleoside inhibitor of HIV reverse transcriptase
Uckun, Fatih M, Tibbles, Heather E, Venkatachalam, Taracad K, Erbeck, Douglas
Published in Arzneimittel-Forschung (01.01.2007)
Published in Arzneimittel-Forschung (01.01.2007)
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Anti-proliferative and anti-leukemic activity of DDE46 (compound WHI-07), a novel bromomethoxylated arylphosphate derivative of zidovudine, and related compounds. Studies using human acute lymphoblastic leukemia cells and the zebrafish model
Benyumov, Alexey O, Venkatachalam, Taracad K, Grigoriants, Olga O, Vassilev, Alexei O, Tibbles, Heather E, Downs, Suzanne, Dumezb, Darin, Uckun, Fatih M
Published in Arzneimittel-Forschung (2005)
Published in Arzneimittel-Forschung (2005)
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