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Thorne, Lucy G, Reuschl, Ann‐Kathrin, Zuliani‐Alvarez, Lorena, Whelan, Matthew V X, Turner, Jane, Noursadeghi, Mahdad, Jolly, Clare, Towers, Greg J
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Published in The EMBO journal (02.08.2021)
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Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?
Sumner, Rebecca P, Thorne, Lucy G, Fink, Doug L, Khan, Hataf, Milne, Richard S, Towers, Greg J
Published in Frontiers in immunology (06.10.2017)
Published in Frontiers in immunology (06.10.2017)
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SARS-CoV-2 variant biology: immune escape, transmission and fitness
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Published in Nature reviews. Microbiology (01.03.2023)
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Interleukin 18 Coexpression during Respiratory Syncytial Virus Infection Results in Enhanced Disease Mediated by Natural Killer Cells
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Published in Journal of Virology (01.04.2010)
Published in Journal of Virology (01.04.2010)
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SARS-CoV-2 evolution influences GBP and IFITM sensitivity
Mesner, Dejan, Reuschl, Ann-Kathrin, Whelan, Matthew V X, Bronzovich, Taylor, Haider, Tafhima, Thorne, Lucy G, Ragazzini, Roberta, Bonfanti, Paola, Towers, Greg J, Jolly, Clare
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2023)
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Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells
Petrillo, Carolina, Thorne, Lucy G., Unali, Giulia, Schiroli, Giulia, Giordano, Anna M.S., Piras, Francesco, Cuccovillo, Ivan, Petit, Sarah J., Ahsan, Fatima, Noursadeghi, Mahdad, Clare, Simon, Genovese, Pietro, Gentner, Bernhard, Naldini, Luigi, Towers, Greg J., Kajaste-Rudnitski, Anna
Published in Cell stem cell (06.12.2018)
Published in Cell stem cell (06.12.2018)
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Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike
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Published in EMBO reports (06.10.2022)
Published in EMBO reports (06.10.2022)
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Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2
Thorne, Lucy G, Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Zuliani-Alvarez, Lorena, Polacco, Ben, Pelin, Adrian, Batra, Jyoti, Whelan, Matthew V X, Hosmillo, Myra, Fossati, Andrea, Ragazzini, Roberta, Jungreis, Irwin, Ummadi, Manisha, Rojc, Ajda, Turner, Jane, Bischof, Marie L, Obernier, Kirsten, Braberg, Hannes, Soucheray, Margaret, Richards, Alicia, Chen, Kuei-Ho, Harjai, Bhavya, Memon, Danish, Hiatt, Joseph, Rosales, Romel, McGovern, Briana L, Jahun, Aminu, Fabius, Jacqueline M, White, Kris, Goodfellow, Ian G, Takeuchi, Yasu, Bonfanti, Paola, Shokat, Kevan, Jura, Natalia, Verba, Klim, Noursadeghi, Mahdad, Beltrao, Pedro, Kellis, Manolis, Swaney, Danielle L, García-Sastre, Adolfo, Jolly, Clare, Towers, Greg J, Krogan, Nevan J
Published in Nature (London) (14.04.2022)
Published in Nature (London) (14.04.2022)
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Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
Reuschl, Ann-Kathrin, Thorne, Lucy G, Whelan, Matthew V X, Ragazzini, Roberta, Furnon, Wilhelm, Cowton, Vanessa M, De Lorenzo, Giuditta, Mesner, Dejan, Turner, Jane L E, Dowgier, Giulia, Bogoda, Nathasha, Bonfanti, Paola, Palmarini, Massimo, Patel, Arvind H, Jolly, Clare, Towers, Greg J
Published in Nature microbiology (01.02.2024)
Published in Nature microbiology (01.02.2024)
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Evolution of enhanced innate immune evasion by SARS-CoV-2
Thorne, Lucy G, Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Zuliani-Alvarez, Lorena, Polacco, Ben, Pelin, Adrian, Batra, Jyoti, Whelan, Matthew V X, Hosmillo, Myra, Fossati, Andrea, Ragazzini, Roberta, Jungreis, Irwin, Ummadi, Manisha, Rojc, Ajda, Turner, Jane, Bischof, Marie L, Obernier, Kirsten, Braberg, Hannes, Soucheray, Margaret, Richards, Alicia, Chen, Kuei-Ho, Harjai, Bhavya, Memon, Danish, Hiatt, Joseph, Rosales, Romel, McGovern, Briana L, Jahun, Aminu, Fabius, Jacqueline M, White, Kris, Goodfellow, Ian G, Takeuchi, Yasu, Bonfanti, Paola, Shokat, Kevan, Jura, Natalia, Verba, Klim, Noursadeghi, Mahdad, Beltrao, Pedro, Kellis, Manolis, Swaney, Danielle L, García-Sastre, Adolfo, Jolly, Clare, Towers, Greg J, Krogan, Nevan J
Published in Nature (London) (17.02.2022)
Published in Nature (London) (17.02.2022)
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Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2
Dicken, Samuel J, Murray, Matthew J, Thorne, Lucy G, Reuschl, Ann-Kathrin, Forrest, Calum, Ganeshalingham, Maaroothen, Muir, Luke, Kalemera, Mphatso D, Palor, Machaela, McCoy, Laura E, Jolly, Clare, Towers, Greg J, Reeves, Matthew B, Grove, Joe
Published in bioRxiv (22.03.2021)
Published in bioRxiv (22.03.2021)
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SARS-CoV-2 variants evolve convergent strategies to remodel the host response
Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Polacco, Benjamin J., Thorne, Lucy G., Ummadi, Manisha R., Ye, Chengjin, Rosales, Romel, Pelin, Adrian, Batra, Jyoti, Jang, Gwendolyn M., Xu, Jiewei, Moen, Jack M., Richards, Alicia L., Zhou, Yuan, Harjai, Bhavya, Stevenson, Erica, Rojc, Ajda, Ragazzini, Roberta, Whelan, Matthew V.X., Furnon, Wilhelm, De Lorenzo, Giuditta, Cowton, Vanessa, Syed, Abdullah M., Ciling, Alison, Deutsch, Noa, Pirak, Daniel, Dowgier, Giulia, Mesner, Dejan, Turner, Jane L., McGovern, Briana L., Rodriguez, M. Luis, Leiva-Rebollo, Rocio, Dunham, Alistair S., Zhong, Xiaofang, Eckhardt, Manon, Fossati, Andrea, Liotta, Nicholas F., Kehrer, Thomas, Cupic, Anastasija, Rutkowska, Magdalena, Mena, Ignacio, Aslam, Sadaf, Hoffert, Alyssa, Foussard, Helene, Olwal, Charles Ochieng’, Huang, Weiqing, Zwaka, Thomas, Pham, John, Lyons, Molly, Donohue, Laura, Griffin, Aliesha, Nugent, Rebecca, Holden, Kevin, Deans, Robert, Aviles, Pablo, Lopez-Martin, Jose A., Jimeno, Jose M., Obernier, Kirsten, Fabius, Jacqueline M., Soucheray, Margaret, Hüttenhain, Ruth, Jungreis, Irwin, Kellis, Manolis, Echeverria, Ignacia, Verba, Kliment, Bonfanti, Paola, Beltrao, Pedro, Sharan, Roded, Doudna, Jennifer A., Martinez-Sobrido, Luis, Patel, Arvind H., Palmarini, Massimo, Miorin, Lisa, White, Kris, Swaney, Danielle L., Garcia-Sastre, Adolfo, Jolly, Clare, Zuliani-Alvarez, Lorena, Towers, Greg J., Krogan, Nevan J.
Published in Cell (12.10.2023)
Published in Cell (12.10.2023)
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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant
Reuschl, Ann-Kathrin, Thorne, Lucy G, Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Hiatt, Joseph, Soucheray, Margaret, Turner, Jane, Fabius, Jacqueline M, Nguyen, Gina T, Swaney, Danielle L, Rosales, Romel, White, Kris M, Avilés, Pablo, Kirby, Ilsa T, Melnyk, James E, Shi, Ying, Zhang, Ziyang, Shokat, Kevan M, García-Sastre, Adolfo, Jolly, Clare, Towers, Gregory J, Krogan, Nevan J
Published in bioRxiv (04.02.2021)
Published in bioRxiv (04.02.2021)
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Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization
Varona, José F, Landete, Pedro, Lopez-Martin, Jose A, Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucía Fernández, Torralba, Miguel, Fortún, Jesús, Vates, Roberto, Barberán, José, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemí, Porras, Lourdes, Gijón, Paloma, Monereo, Alfonso, Abad, Daniel, Zúñiga, Sonia, Sola, Isabel, Rodon, Jordi, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, María José, de Rivas, Beatriz, Girón de Velasco, Patricia, Sopesén, Belén, Nieto, Antonio, Gómez, Javier, Avilés, Pablo, Lubomirov, Rubin, White, Kris M, Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G, Jolly, Clare, Towers, Greg J, Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Enjuanes, Luis, Fernández-Sousa, Jose M, Krogan, Nevan J, Jimeno, José M, García-Sastre, Adolfo
Published in medRxiv : the preprint server for health sciences (25.05.2021)
Published in medRxiv : the preprint server for health sciences (25.05.2021)
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Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant
Thorne, Lucy G, Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Zuliani-Alvarez, Lorena, Polacco, Ben, Pelin, Adrian, Batra, Jyoti, Whelan, Matthew V X, Ummadi, Manisha, Rojc, Ajda, Turner, Jane, Obernier, Kirsten, Braberg, Hannes, Soucheray, Margaret, Richards, Alicia, Chen, Kuei-Ho, Harjai, Bhavya, Memon, Danish, Hosmillo, Myra, Hiatt, Joseph, Jahun, Aminu, Goodfellow, Ian G, Fabius, Jacqueline M, Shokat, Kevan, Jura, Natalia, Verba, Klim, Noursadeghi, Mahdad, Beltrao, Pedro, Swaney, Danielle L, Garcia-Sastre, Adolfo, Jolly, Clare, Towers, Greg J, Krogan, Nevan J
Published in bioRxiv (07.06.2021)
Published in bioRxiv (07.06.2021)
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Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories
Bouhaddou, Mehdi, Ann-Kathrin Reuschl, Polacco, Benjamin J, Thorne, Lucy G, Ummadi, Manisha R, Ye, Chengjin, Romel Rosales Ramirez, Pelin, Adrian, Batra, Jyoti, Jang, Gwendolyn M, Xu, Jiewei, Moen, Jack M, Richards, Alicia L, Zhou, Yuan, Harjai, Bhavya, Stevenson, Erica, Rojc, Ajda, Ragazzini, Roberta, Whelan, Matthew Vx, Furnon, Wilhelm, De Lorenzo, Giuditta, Cowton, Vanessa, Syed, Abdullah M, Ciling, Alison, Deutsch, Noa, Pirak, Daniel, Dowgier, Giulia, Mesner, Dejan, Turner, Jane L, Mcgovern, Briana L, Rodriguez, M Luis, Leiva-Rebollo, Rocio, Dunham, Alistair S, Zhong, Xiaofang, Eckhardt, Manon, Fossati, Andrea, Liotta, Nicholas, Kehrer, Thomas, Cupic, Anastasija, Rutkowska, Magda, Mena, Nacho, Aslam, Sadaf, Hoffert, Alyssa, Foussard, Helene, Pham, John, Lyons, Molly, Donahue, Laura, Griffin, Aliesha, Nugent, Rebecca, Holden, Kevin, Deans, Robert, Aviles, Pablo, Lopez-Martin, Jose Antonio, Jimeno, Jose M, Obernier, Kirsten, Fabius, Jacqueline M, Soucheray, Margaret, Huttenhain, Ruth, Jungreis, Irwin, Kellis, Manolis, Echeverria, Ignacia, Verba, Kliment, Bonfanti, Paola, Beltrao, Pedro, Sharan, Roded, Doudna, Jennifer A, Martinez-Sobrido, Luis, Patel, Arvind, Palmarini, Massimo, Miorin, Lisa, White, Kris, Swaney, Danielle L, Garcia-Sastre, Adolfo, Jolly, Clare, Zuliani-Alvarez, Lorena, Towers, Greg J, Krogan, Nevan J
Published in bioRxiv (21.10.2022)
Published in bioRxiv (21.10.2022)
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