Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization
Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
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Journal Article
Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis
Thompson, Thelma, Tovar, Christian, Yang, Hong, Carvajal, Daisy, Vu, Binh T., Xu, Qunli, Wahl, Geoffrey M., Heimbrook, David C., Vassilev, Lyubomir T.
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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Journal Article
1,25-dihydroxyvitamin D3 enhances the apoptotic activity of MDM2 antagonist nutlin-3a in acute myeloid leukemia cells expressing wild-type p53
Thompson, Thelma, Andreeff, Michael, Studzinski, George P, Vassilev, Lyubomir T
Published in Molecular cancer therapeutics (01.05.2010)
Published in Molecular cancer therapeutics (01.05.2010)
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Journal Article
Tumor suppressor p53 status does not determine the differentiation-associated G1 cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D3 and antioxidants
Thompson, Thelma, Danilenko, Michael, Vassilev, Lyubomir, Studzinski, George P.
Published in Cancer biology & therapy (15.08.2010)
Published in Cancer biology & therapy (15.08.2010)
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Journal Article
Tumor suppressor p53 status does not determine the differentiation-associated G 1 cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D 3 and antioxidants
Thompson, Thelma, Danilenko, Michael, Vassilev, Lyubomir, Studzinski, George P.
Published in Cancer biology & therapy (15.08.2010)
Published in Cancer biology & therapy (15.08.2010)
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Journal Article
Abstract 4727: Antitumor activity of the MDM2 antagonist, RG7112
Tovar, Christian, Filipovic, Zoran, Thompson, Thelma, Higgins, Brian, Kolinsky, Kenneth, Packman, Kathryn, Deo, Dayanand, Vu, Binh, Graves, Bradford, Vassilev, Lyubomir T.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Activation of the p53 pathway by small-moleculeinduced MDM2 and MDMX dimerization
Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
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Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
Journal Article
Abstract C128: Small-molecule antagonists of MDM2 and MDMX
Thompson, Thelma, Graves, Bradford, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Huang, Kuo-Sen, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
A new series of potent oxindole inhibitors of CDK2
LUK, Kin-Chun, SIMCOX, Mary Ellen, SCHUTT, Andy, ROWAN, Karen, THOMPSON, Thelma, YI CHEN, KAMMLOTT, Ursula, DEPINTO, Wanda, DUNTEN, Pete, DERMATAKIS, Apos
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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Journal Article
A New Series of Potent Oxindole Inhibitors of CDK2
Luk, Kin-Chun, Simcox, Mary Ellen, Schutt, Andy, Rowan, Karen, Thompson, Thelma, Chen, Yi, Kammlott, Ursula, DePinto, Wanda, Dunten, Pete, Dermatakis, Apos
Published in Bioorganic & medicinal chemistry (22.06.2004)
Published in Bioorganic & medicinal chemistry (22.06.2004)
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