2‑Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria
Zeczycki, Tonya N., Milton, Morgan E., Jung, David, Thompson, Richele J., Jaimes, Felicia E., Hondros, Alexander D., Palethorpe, Samantha, Melander, Christian, Cavanagh, John
Published in Biochemistry (Easton) (20.12.2022)
Published in Biochemistry (Easton) (20.12.2022)
Get full text
Journal Article
The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism
Draughn, G. Logan, Milton, Morgan E., Feldmann, Erik A., Bobay, Benjamin G., Roth, Braden M., Olson, Andrew L., Thompson, Richele J., Actis, Luis A., Davies, Christopher, Cavanagh, John
Published in Journal of molecular biology (16.03.2018)
Published in Journal of molecular biology (16.03.2018)
Get full text
Journal Article
The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis
Milton, Morgan E., Draughn, G. Logan, Bobay, Benjamin G., Stowe, Sean D., Olson, Andrew L., Feldmann, Erik A., Thompson, Richele J., Myers, Katherine H., Santoro, Michael T., Kearns, Daniel B., Cavanagh, John
Published in Journal of molecular biology (17.01.2020)
Published in Journal of molecular biology (17.01.2020)
Get full text
Journal Article
Identification of BfmR, a Response Regulator Involved in Biofilm Development, as a Target for a 2‑Aminoimidazole-Based Antibiofilm Agent
Thompson, Richele J, Bobay, Benjamin G, Stowe, Sean D, Olson, Andrew L, Peng, Lingling, Su, Zhaoming, Actis, Luis A, Melander, Christian, Cavanagh, John
Published in Biochemistry (Easton) (11.12.2012)
Published in Biochemistry (Easton) (11.12.2012)
Get full text
Journal Article
Small-Molecule Suppression of β‑Lactam Resistance in Multidrug-Resistant Gram-Negative Pathogens
Brackett, Christopher M, Melander, Roberta J, An, Il Hwan, Krishnamurthy, Aparna, Thompson, Richele J, Cavanagh, John, Melander, Christian
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
Get full text
Journal Article
Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2‐aminoimidazole‐based compounds
Milton, Morgan E., Allen, C. Leigh, Feldmann, Erik A., Bobay, Benjamin G., Jung, David K., Stephens, Matthew D., Melander, Roberta J., Theisen, Kelly E., Zeng, Daina, Thompson, Richele J., Melander, Christian, Cavanagh, John
Published in Molecular microbiology (01.10.2017)
Published in Molecular microbiology (01.10.2017)
Get full text
Journal Article
Anti-biofilm compounds derived from marine sponges
Stowe, Sean D, Richards, Justin J, Tucker, Ashley T, Thompson, Richele, Melander, Christian, Cavanagh, John
Published in Marine Drugs (01.10.2011)
Published in Marine Drugs (01.10.2011)
Get full text
Journal Article
Book Review
Structure and DNA-Binding Traits of the Transition State Regulator AbrB
Olson, Andrew L., Tucker, Ashley T., Bobay, Benjamin G., Soderblom, Erik J., Moseley, M. Arthur, Thompson, Richele J., Cavanagh, John
Published in Structure (London) (04.11.2014)
Published in Structure (London) (04.11.2014)
Get full text
Journal Article
A DNA Mimic: The Structure and Mechanism of Action for the Anti-Repressor Protein AbbA
Tucker, Ashley T., Bobay, Benjamin G., Banse, Allison V., Olson, Andrew L., Soderblom, Erik J., Moseley, M. Arthur, Thompson, Richele J., Varney, Kristen M., Losick, Richard, Cavanagh, John
Published in Journal of molecular biology (01.05.2014)
Published in Journal of molecular biology (01.05.2014)
Get full text
Journal Article
Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp
Milton, Morgan E, Minrovic, Bradley M, Harris, Danni L, Kang, Brian, Jung, David, Lewis, Caleb P, Thompson, Richele J, Melander, Roberta J, Zeng, Daina, Melander, Christian, Cavanagh, John
Published in Frontiers in molecular biosciences (13.02.2018)
Published in Frontiers in molecular biosciences (13.02.2018)
Get full text
Journal Article
Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii
Stowe, Sean D, Thompson, Richele J, Peng, Lingling, Su, Zhaoming, Blackledge, Meghan S, Draughn, G Logan, Coe, William H, Johannes, Eva, Lapham, Valerie K, Mackenzie, John, Melander, Christian, Cavanagh, John
Published in Current drug delivery (01.01.2015)
Published in Current drug delivery (01.01.2015)
Get more information
Journal Article
Long range dynamic effects of point-mutations trap a response regulator in an active conformation
Bobay, Benjamin G., Thompson, Richele J., Hoch, James A., Cavanagh, John
Published in FEBS letters (08.10.2010)
Published in FEBS letters (08.10.2010)
Get full text
Journal Article
Insights into the Nature of DNA Binding of AbrB-like Transcription Factors
Sullivan, Daniel M., Bobay, Benjamin G., Kojetin, Douglas J., Thompson, Richele J., Rance, Mark, Strauch, Mark A., Cavanagh, John
Published in Structure (London) (12.11.2008)
Published in Structure (London) (12.11.2008)
Get full text
Journal Article
Co-Evolving Motions at Protein−Protein Interfaces of Two-Component Signaling Systems Identified by Covariance Analysis
Szurmant, Hendrik, Bobay, Benjamin G, White, Robert A, Sullivan, Daniel M, Thompson, Richele J, Hwa, Terence, Hoch, James A, Cavanagh, John
Published in Biochemistry (Easton) (29.07.2008)
Published in Biochemistry (Easton) (29.07.2008)
Get full text
Journal Article
Chemical shift assignments and secondary structure prediction of the C-terminal domain of the response regulator BfmR from Acinetobacter baumannii
Olson, Andrew L., Thompson, Richele J., Melander, Christian, Cavanagh, John
Published in Biomolecular NMR assignments (01.04.2014)
Published in Biomolecular NMR assignments (01.04.2014)
Get full text
Journal Article
In-Line Desalting Mass Spectrometry for the Study of Noncovalent Biological Complexes
Cavanagh, John, Benson, Linda M, Thompson, Richele, Naylor, Stephen
Published in Analytical chemistry (Washington) (15.07.2003)
Published in Analytical chemistry (Washington) (15.07.2003)
Get full text
Journal Article
Structural Characterization of the Conformational Change in Calbindin-D28k upon Calcium Binding Using Differential Surface Modification Analyzed by Mass Spectrometry
Hobbs, Carey A, Deterding, Leesa J, Perera, Lalith, Bobay, Benjamin G, Thompson, Richele J, Darden, Thomas A, Cavanagh, John, Tomer, Kenneth B
Published in Biochemistry (Easton) (15.09.2009)
Published in Biochemistry (Easton) (15.09.2009)
Get full text
Journal Article