The JAK/STAT pathway in obesity and diabetes
Gurzov, Esteban N., Stanley, William J., Pappas, Evan G., Thomas, Helen E., Gough, Daniel J.
Published in The FEBS journal (01.08.2016)
Published in The FEBS journal (01.08.2016)
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Protein tyrosine phosphatases: molecular switches in metabolism and diabetes
Gurzov, Esteban N, Stanley, William J, Brodnicki, Thomas C, Thomas, Helen E
Published in Trends in endocrinology and metabolism (01.01.2015)
Published in Trends in endocrinology and metabolism (01.01.2015)
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Transplantation sites for human and murine islets
Stokes, Rebecca A., Cheng, Kim, Lalwani, Amit, Swarbrick, Michael M., Thomas, Helen E., Loudovaris, Thomas, Kay, Tom W., Hawthorne, Wayne J., O’Connell, Philip J., Gunton, Jenny E.
Published in Diabetologia (01.10.2017)
Published in Diabetologia (01.10.2017)
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Monitoring immunomodulation strategies in type 1 diabetes
Krishnamurthy, Balasubramanian, Lacorcia, Matthew, Kay, Thomas W H, Thomas, Helen E, Mannering, Stuart I
Published in Frontiers in immunology (06.06.2023)
Published in Frontiers in immunology (06.06.2023)
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Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans
Bensellam, Mohammed, Shi, Yan-Chuan, Chan, Jeng Yie, Laybutt, D. Ross, Chae, Heeyoung, Abou-Samra, Michel, Pappas, Evan G., Thomas, Helen E., Gilon, Patrick, Jonas, Jean-Christophe
Published in Diabetologia (01.12.2019)
Published in Diabetologia (01.12.2019)
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The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice
Ge, Tingting, Jhala, Gaurang, Fynch, Stacey, Akazawa, Satoru, Litwak, Sara, Pappas, Evan G, Catterall, Tara, Vakil, Ishan, Long, Andrew J, Olson, Lisa M, Krishnamurthy, Balasubramanian, Kay, Thomas W, Thomas, Helen E
Published in Frontiers in immunology (04.12.2020)
Published in Frontiers in immunology (04.12.2020)
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TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes
Trivedi, Prerak, Jhala, Gaurang, De George, David J, Chiu, Chris, Selck, Claudia, Ge, Tingting, Catterall, Tara, Elkerbout, Lorraine, Boon, Louis, Joller, Nicole, Kay, Thomas W, Thomas, Helen E, Krishnamurthy, Balasubramanian
Published in Frontiers in immunology (12.03.2024)
Published in Frontiers in immunology (12.03.2024)
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Phlda3 regulates beta cell survival during stress
Bensellam, Mohammed, Chan, Jeng Yie, Lee, Kailun, Joglekar, Mugdha V, Hardikar, Anandwardhan A, Loudovaris, Thomas, Thomas, Helen E, Jonas, Jean-Christophe, Laybutt, D Ross
Published in Scientific reports (06.09.2019)
Published in Scientific reports (06.09.2019)
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Development of a standardized MRI protocol for pancreas assessment in humans
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Published in PloS one (24.08.2021)
Published in PloS one (24.08.2021)
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Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells
Schiesser, Jacqueline V, Loudovaris, Thomas, Thomas, Helen E, Elefanty, Andrew G, Stanley, Edouard G
Published in Scientific reports (15.04.2021)
Published in Scientific reports (15.04.2021)
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Replacing murine insulin 1 with human insulin protects NOD mice from diabetes
Elso, Colleen M, Scott, Nicholas A, Mariana, Lina, Masterman, Emma I, Sutherland, Andrew P R, Thomas, Helen E, Mannering, Stuart I
Published in PloS one (10.12.2019)
Published in PloS one (10.12.2019)
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Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans
Simeonovic, Charmaine J, Popp, Sarah K, Starrs, Lora M, Brown, Debra J, Ziolkowski, Andrew F, Ludwig, Barbara, Bornstein, Stefan R, Wilson, J Dennis, Pugliese, Alberto, Kay, Thomas W H, Thomas, Helen E, Loudovaris, Thomas, Choong, Fui Jiun, Freeman, Craig, Parish, Christopher R
Published in PloS one (07.02.2018)
Published in PloS one (07.02.2018)
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Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix
Singh, Reena, Cottle, Louise, Loudovaris, Thomas, Xiao, Di, Yang, Pengyi, Thomas, Helen E., Kebede, Melkam A., Thorn, Peter
Published in Stem cells translational medicine (01.03.2021)
Published in Stem cells translational medicine (01.03.2021)
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Inhibition of Y1 receptor signaling improves islet transplant outcome
Loh, Kim, Shi, Yan-Chuan, Walters, Stacey, Bensellam, Mohammed, Lee, Kailun, Dezaki, Katsuya, Nakata, Masanori, Ip, Chi Kin, Chan, Jeng Yie, Gurzov, Esteban N, Thomas, Helen E, Waibel, Michaela, Cantley, James, Kay, Thomas W, Yada, Toshihiko, Laybutt, D Ross, Grey, Shane T, Herzog, Herbert
Published in Nature communications (08.09.2017)
Published in Nature communications (08.09.2017)
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Type I Interferon Signaling Is Required for Dacryoadenitis in the Nonobese Diabetic Mouse Model of Sjögren Syndrome
Chaly, Yury, Barr, Jennifer Y, Sullivan, David A, Thomas, Helen E, Brodnicki, Thomas C, Lieberman, Scott M
Published in International journal of molecular sciences (20.10.2018)
Published in International journal of molecular sciences (20.10.2018)
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Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice
Jhala, Gaurang, Selck, Claudia, Chee, Jonathan, Kwong, Chun-Ting J, Pappas, Evan G, Thomas, Helen E, Kay, Thomas W H, Krishnamurthy, Balasubramanian
Published in Frontiers in immunology (25.03.2021)
Published in Frontiers in immunology (25.03.2021)
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Desmoglein-2 is important for islet function and β-cell survival
Myo Min, Kay K, Rojas-Canales, Darling, Penko, Daniella, DeNichilo, Mark, Cockshell, Michaelia P, Ffrench, Charlie B, Thompson, Emma J, Asplund, Olof, Drogemuller, Christopher J, Prasad, Rashmi B, Groop, Leif, Grey, Shane T, Thomas, Helen E, Loudovaris, Thomas, Kay, Thomas W, Mahoney, My G, Jessup, Claire F, Coates, P Toby, Bonder, Claudine S
Published in Cell death & disease (29.10.2022)
Published in Cell death & disease (29.10.2022)
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Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells
Augstein, Petra, Naselli, Gaetano, Loudovaris, Thomas, Hawthorne, Wayne J, Campbell, Peter, Bandala-Sanchez, Esther, Rogers, Kelly, Heinke, Peter, Thomas, Helen E, Kay, Thomas W, Harrison, Leonard C
Published in Diabetes research and clinical practice (01.12.2015)
Published in Diabetes research and clinical practice (01.12.2015)
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