Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model
Sussan, Thomas E, Gajghate, Sachin, Thimmulappa, Rajesh K, Ma, Jinfang, Kim, Jung-Hyun, Sudini, Kuladeep, Consolini, Nicola, Cormier, Stephania A, Lomnicki, Slawo, Hasan, Farhana, Pekosz, Andrew, Biswal, Shyam
Published in PloS one (04.02.2015)
Published in PloS one (04.02.2015)
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Journal Article
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer
Singh, Anju, Misra, Vikas, Thimmulappa, Rajesh K, Lee, Hannah, Ames, Stephen, Hoque, Mohammad O, Herman, James G, Baylin, Stephen B, Sidransky, David, Gabrielson, Edward, Brock, Malcolm V, Biswal, Shyam
Published in PLoS medicine (01.10.2006)
Published in PLoS medicine (01.10.2006)
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Journal Article
NRF2, p53, and p16: Predictive biomarkers to stratify human papillomavirus associated head and neck cancer patients for de-escalation of cancer therapy
Ramesh, Pushkal S., Devegowda, Devananda, Singh, Anju, Thimmulappa, Rajesh K.
Published in Critical reviews in oncology/hematology (01.04.2020)
Published in Critical reviews in oncology/hematology (01.04.2020)
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Journal Article
Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK
Sivanantham, Ayyanar, Pattarayan, Dhamotharan, Bethunaickan, Ramalingam, Kar, Amrita, Mahapatra, Santanu Kar, Thimmulappa, Rajesh K., Palanichamy, Rajaguru, Rajasekaran, Subbiah
Published in Journal of cellular physiology (01.05.2019)
Published in Journal of cellular physiology (01.05.2019)
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Journal Article
Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19
Thimmulappa, Rajesh K., Mudnakudu-Nagaraju, Kiran Kumar, Shivamallu, Chandan, Subramaniam, K.J.Thirumalai, Radhakrishnan, Arun, Bhojraj, Suresh, Kuppusamy, Gowthamarajan
Published in Heliyon (01.02.2021)
Published in Heliyon (01.02.2021)
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Journal Article
Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching
Wei, Yanhong, Gong, Junsong, Thimmulappa, Rajesh K, Kosmider, Beata, Biswal, Shyam, Duh, Elia J
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2013)
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Journal Article
Forced expression of microRNA-221-3p exerts protective effects against manganese-induced cytotoxicity in human lung epithelial cells
Gandhi, Deepa, Bhandari, Sneha, Mishra, Sehal, Rudrashetti, Ashwinkumar P., Vetrivel, Umashankar, Thimmulappa, Rajesh K., Rajasekaran, Subbiah
Published in Toxicology and applied pharmacology (01.04.2024)
Published in Toxicology and applied pharmacology (01.04.2024)
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Journal Article
Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A
Wei, Yanhong, Gong, Junsong, Xu, Zhenhua, Thimmulappa, Rajesh K., Mitchell, Katherine L., Welsbie, Derek S., Biswal, Shyam, Duh, Elia J.
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
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Journal Article
Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model
Harvey, Christopher J, Thimmulappa, Rajesh K, Sethi, Sanjay, Kong, Xiaoni, Yarmus, Lonny, Brown, Robert H, Feller-Kopman, David, Wise, Robert, Biswal, Shyam
Published in Science translational medicine (13.04.2011)
Published in Science translational medicine (13.04.2011)
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Journal Article
NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation
Kim, Jung-Hyun, Thimmulappa, Rajesh K, Kumar, Vineet, Cui, Wanchang, Kumar, Sarvesh, Kombairaju, Ponvijay, Zhang, Hao, Margolick, Joseph, Matsui, William, Macvittie, Thomas, Malhotra, Sanjay V, Biswal, Shyam
Published in The Journal of clinical investigation (01.02.2014)
Published in The Journal of clinical investigation (01.02.2014)
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Journal Article
Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis
KONG, Xiaoni, THIMMULAPPA, Rajesh, CRACIUN, Florin, HARVEY, Christopher, SINGH, Anju, KOMBAIRAJU, Ponvijay, REDDY, Sekhar P, REMICK, Daniel, BISWAL, Shyam
Published in American journal of respiratory and critical care medicine (15.10.2011)
Published in American journal of respiratory and critical care medicine (15.10.2011)
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Journal Article
RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy
SINGH, Anju, BOLDIN-ADAMSKY, Swetlana, GABRIELSON, Edward, FEINSTEIN, Elena, BISWAL, Shyam, THIMMULAPPA, Rajesh K, RATH, Srikanta K, ASHUSH, Hagit, COULTER, Jonathan, BLACKFORD, Amanda, GOODMAN, Steven N, BUNZ, Fred, WATSON, Walter H
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Journal Article
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
Malhotra, Deepti, Thimmulappa, Rajesh K, Mercado, Nicolas, Ito, Kazuhiro, Kombairaju, Ponvijay, Kumar, Sarvesh, Ma, Jinfang, Feller-Kopman, David, Wise, Robert, Barnes, Peter, Biswal, Shyam
Published in The Journal of clinical investigation (01.11.2011)
Published in The Journal of clinical investigation (01.11.2011)
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Journal Article
Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1
Page, Audrey, Volchkova, Valentina A, Reid, Saint Patrick, Mateo, Mathieu, Bagnaud-Baule, Audrey, Nemirov, Kirill, Shurtleff, Amy C, Lawrence, Philip, Reynard, Oliver, Ottmann, Michele, Lotteau, Vincent, Biswal, Shyam S, Thimmulappa, Rajesh K, Bavari, Sina, Volchkov, Viktor E
Published in Cell reports (Cambridge) (27.03.2014)
Published in Cell reports (Cambridge) (27.03.2014)
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Journal Article
Human papillomavirus-driven repression of NRF2 signalling confers chemo-radio sensitivity and predicts prognosis in head and neck squamous cell carcinoma
Ramesh, Pushkal S., Bovilla, Venugopal R., Swamy, Vikas H., Manoli, Nandini N., Dasegowda, Krishnappa B., Siddegowda, Siddegowda M., Chandrashekarappa, Shilpa, Somasundara, Vishveshwara M., Kabekkodu, Shama P., Rajesh, R., Devegowda, Devanand, Thimmulappa, Rajesh K.
Published in Free radical biology & medicine (20.08.2023)
Published in Free radical biology & medicine (20.08.2023)
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Journal Article
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
Thimmulappa, Rajesh K, Lee, Hannah, Rangasamy, Tirumalai, Reddy, Sekhar P, Yamamoto, Masayuki, Kensler, Thomas W, Biswal, Shyam
Published in The Journal of clinical investigation (01.04.2006)
Published in The Journal of clinical investigation (01.04.2006)
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Journal Article