Search Results - "Thieu, Tho V" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors

Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors

by Mesaros, Eugen F, Thieu, Tho V, Wells, Gregory J, Zificsak, Craig A, Wagner, Jason C, Breslin, Henry J, Tripathy, Rabindranath, Diebold, James L, McHugh, Robert J, Wohler, Ashley T, Quail, Matthew R, Wan, Weihua, Lu, Lihui, Huang, Zeqi, Albom, Mark S, Angeles, Thelma S, Wells-Knecht, Kevin J, Aimone, Lisa D, Cheng, Mangeng, Ator, Mark A, Ott, Gregory R, Dorsey, Bruce D
Published in Journal of medicinal chemistry (12.01.2012)

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Journal Article

2,7-Disubstituted-pyrrolo[2,1-f][1,2,4]triazines: New Variant of an Old Template and Application to the Discovery of Anaplastic Lymphoma Kinase (ALK) Inhibitors with in Vivo Antitumor Activity

2,7-Disubstituted-pyrrolo[2,1-f][1,2,4]triazines: New Variant of an Old Template and Application to the Discovery of Anaplastic Lymphoma Kinase (ALK) Inhibitors with in Vivo Antitumor Activity

by Ott, Gregory R, Wells, Gregory J, Thieu, Tho V, Quail, Matthew R, Lisko, Joseph G, Mesaros, Eugen F, Gingrich, Diane E, Ghose, Arup K, Wan, Weihua, Lu, Lihui, Cheng, Mangeng, Albom, Mark S, Angeles, Thelma S, Huang, Zeqi, Aimone, Lisa D, Ator, Mark A, Ruggeri, Bruce A, Dorsey, Bruce D
Published in Journal of medicinal chemistry (22.09.2011)

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7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa

7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa

by Lee, Yu-Kai, Parks, Daniel J, Lu, Tianbao, Thieu, Tho V, Markotan, Thomas, Pan, Wenxi, McComsey, David F, Milkiewicz, Karen L, Crysler, Carl S, Ninan, Nisha, Abad, Marta C, Giardino, Edward C, Maryanoff, Bruce E, Damiano, Bruce P, Player, Mark R
Published in Journal of medicinal chemistry (24.01.2008)

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2,7-Pyrrolo[2,1- f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation

2,7-Pyrrolo[2,1- f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation

by Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Breslin, Henry J., Gingrich, Diane E., Huang, Zeqi, Lisko, Joseph G., Mason, Jennifer L., Milkiewicz, Karen L., Thieu, Tho V., Underiner, Ted L., Wells, Gregory J., Wells-Knecht, Kevin J., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (15.12.2011)

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Journal Article

Amorphous fluoropolymers from tetrafluoroethylene and bulky vinyl esters or vinyl ethers

Amorphous fluoropolymers from tetrafluoroethylene and bulky vinyl esters or vinyl ethers

by Feiring, Andrew E, Wonchoba, Edward R, Fischel, Brian E, Thieu, Tho V, Nassirpour, M.Reza
Published in Journal of fluorine chemistry (01.12.2002)

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Journal Article

Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases

Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases

by Zificsak, Craig A., Gingrich, Diane E., Breslin, Henry J., Dunn, Derek D., Milkiewicz, Karen L., Theroff, Jay P., Thieu, Tho V., Underiner, Ted L., Weinberg, Linda R., Aimone, Lisa D., Albom, Mark S., Mason, Jennifer L., Saville, Lisa, Husten, Jean, Angeles, Thelma S., Finn, James P., Jan, Mahfuza, O’Kane, Teresa M., Dobrzanski, Pawel, Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)

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Journal Article

SUBSTITUTED PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS

SUBSTITUTED PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS

by Xu, Guozhang, Thieu, Tho V, Liu, Zhijie, Gaul, Micheal D
Year of Publication 11.07.2024

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Patent

Substituted pyridine N-oxide derivatives useful as a factor XIa inhibitors

Substituted pyridine N-oxide derivatives useful as a factor XIa inhibitors

by Xu, Guozhang, Thieu, Tho V, Liu, Zhijie, Gaul, Micheal D
Year of Publication 05.03.2024

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Patent

SUBSTITUTED PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS

SUBSTITUTED PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS

by Xu, Guozhang, Thieu, Tho V, Liu, Zhijie, Gaul, Micheal D
Year of Publication 06.10.2022

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Patent

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

by NARGUND, Ravi, MACIELAG, Mark J, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 05.10.2023

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Patent

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

by NARGUND, Ravi, MACIELAG, Mark J, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 31.05.2023

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Patent

Bicyclic Pyridin-2-one and pyrimidin-4-one Derivatives Useful As a Factor XIa Inhibitors

Bicyclic Pyridin-2-one and pyrimidin-4-one Derivatives Useful As a Factor XIa Inhibitors

by Xu, Guozhang, Macielag, Mark J, Thieu, Tho V, Gaul, Micheal D, Liu, Zhijie
Year of Publication 30.03.2023

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Pyridine N-oxide derivatives useful as factor XIa inhibitors

Pyridine N-oxide derivatives useful as factor XIa inhibitors

by Guo, Boying, Xu, Guozhang, Lu, Tianbao, Macielag, Mark J, Thieu, Tho V, Liu, Zhijie, Gaul, Micheal D, Zhang, Jing, Grant, Eugene B
Year of Publication 14.11.2023

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Patent

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

by XU, GUOZHANG, NARGUND, RAVI, LIU, ZHIJIE, MACIELAG, MARK J, THIEU, THO V
Year of Publication 27.01.2022

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Patent

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS

by NARGUND, Ravi, MACIELAG, Mark J, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 27.01.2022

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Patent

PYRIDINE N-OXIDE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

PYRIDINE N-OXIDE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

by Guo, Boying, Xu, Guozhang, Lu, Tianbao, Macielag, Mark J, Thieu, Tho V, Liu, Zhijie, Gaul, Micheal D, Zhang, Jing, Grant, Eugene B
Year of Publication 23.03.2023

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Patent

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

by LU, Tianbao, NARGUND, Ravi, MACIELAG, Mark J, GAUL, Micheal D, GUO, Boying, WALL, Mark, ZHU, Bin, ZHANG, Jing, GAO, Ling Hua, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 21.09.2023

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Patent

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

by LU, Tianbao, NARGUND, Ravi, MACIELAG, Mark J, GAUL, Micheal D, GUO, Boying, WALL, Mark, ZHU, Bin, ZHANG, Jing, GAO, Ling Hua, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 31.05.2023

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Patent

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

by LU, Tianbao, NARGUND, Ravi, MACIELAG, Mark J, GAUL, Micheal D, GUO, Boying, WALL, Mark, ZHU, Bin, ZHANG, Jing, GAO, Ling Hua, LIU, Zhijie, XU, Guozhang, THIEU, Tho V
Year of Publication 27.01.2022

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Patent

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS

by GUO, BOYING, ZHANG, JING, GAO, LING HUA, XU, GUOZHANG, WALL, MARK, NARGUND, RAVI, GAUL, MICHEAL D, LIU, ZHIJIE, LU, TIANBAO, MACIELAG, MARK J, THIEU, THO V, ZHU, BIN
Year of Publication 27.01.2022

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