Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response
Linden, Janette, Stefens, Sanne J. M., Heredia‐Genestar, José María, Ridwan, Yanto, Brandt, Renata M. C., Vliet, Nicole, Beer, Isa, Thiel, Bibi S., Steen, Herman, Cheng, Caroline, Roks, Anton J. M., Danser, A. H. Jan, Essers, Jeroen, Pluijm, Ingrid
Published in Aging cell (01.05.2024)
Published in Aging cell (01.05.2024)
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Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice
van Thiel, Bibi S., de Boer, Martine, Ridwan, Yanto, de Kleijnen, Marion G. J., van Vliet, Nicole, van der Linden, Janette, de Beer, Isa, van Heijningen, Paula M., Vermeij, Wilbert P., Hoeijmakers, Jan H. J., Danser, A. H. Jan, Kanaar, Roland, Duncker, Dirk J., van der Pluijm, Ingrid, Essers, Jeroen
Published in Molecular imaging and biology (01.08.2024)
Published in Molecular imaging and biology (01.08.2024)
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Journal Article
In Vivo Renin Activity Imaging in the Kidney of Progeroid Ercc1 Mutant Mice
van Thiel, Bibi S, van der Linden, Janette, Ridwan, Yanto, Garrelds, Ingrid M, Vermeij, Marcel, Clahsen-van Groningen, Marian C, Qadri, Fatimunnisa, Alenina, Natalia, Bader, Michael, Roks, Anton J M, Danser, A H Jan, Essers, Jeroen, van der Pluijm, Ingrid
Published in International journal of molecular sciences (18.11.2021)
Published in International journal of molecular sciences (18.11.2021)
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The renin–angiotensin system and its involvement in vascular disease
van Thiel, Bibi S., van der Pluijm, Ingrid, te Riet, Luuk, Essers, Jeroen, Danser, A.H. Jan
Published in European journal of pharmacology (15.09.2015)
Published in European journal of pharmacology (15.09.2015)
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Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?
Winkel, Leah C.J., Groen, Harald C., van Thiel, Bibi S., Müller, Cristina, van der Steen, Antonius F.W., Wentzel, Jolanda J., de Jong, Marion, Van der Heiden, Kim
Published in Molecular imaging (01.01.2014)
Published in Molecular imaging (01.01.2014)
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Brain Renin-Angiotensin System: Does It Exist?
van Thiel, Bibi S, Góes Martini, Alexandre, Te Riet, Luuk, Severs, David, Uijl, Estrellita, Garrelds, Ingrid M, Leijten, Frank P J, van der Pluijm, Ingrid, Essers, Jeroen, Qadri, Fatimunnisa, Alenina, Natalia, Bader, Michael, Paulis, Ludovit, Rajkovicova, Romana, Domenig, Oliver, Poglitsch, Marko, Danser, A H Jan
Published in Hypertension (Dallas, Tex. 1979) (01.06.2017)
Published in Hypertension (Dallas, Tex. 1979) (01.06.2017)
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Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema
Ramnath, Natasja W M, van de Luijtgaarden, Koen M, van der Pluijm, Ingrid, van Nimwegen, Menno, van Heijningen, Paula M, Swagemakers, Sigrid M A, van Thiel, Bibi S, Ridwan, Ruziedi Y, van Vliet, Nicole, Vermeij, Marcel, Hawinkels, Luuk J A C, de Munck, Anne, Dzyubachyk, Oleh, Meijering, Erik, van der Spek, Peter, Rottier, Robbert, Yanagisawa, Hiromi, Hendriks, Rudi W, Kanaar, Roland, Rouwet, Ellen V, Kleinjan, Alex, Essers, Jeroen
Published in PloS one (25.09.2014)
Published in PloS one (25.09.2014)
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AT1-receptor blockade, but not renin inhibition, reduces aneurysm growth and cardiac failure in fibulin-4 mice
Te Riet, Luuk, van Deel, Elza D, van Thiel, Bibi S, Moltzer, Els, van Vliet, Nicole, Ridwan, Yanto, van Veghel, Richard, van Heijningen, Paula M, Robertus, Jan Lukas, Garrelds, Ingrid M, Vermeij, Marcel, van der Pluijm, Ingrid, Danser, A H Jan, Essers, Jeroen
Published in Journal of hypertension (01.04.2016)
Published in Journal of hypertension (01.04.2016)
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Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1 Δ/- mice
Wu, Haiyan, van Thiel, Bibi S, Bautista-Niño, Paula K, Reiling, Erwin, Durik, Matej, Leijten, Frank P J, Ridwan, Yanto, Brandt, Renata M C, van Steeg, Harry, Dollé, Martijn E T, Vermeij, Wilbert P, Hoeijmakers, Jan H J, Essers, Jeroen, van der Pluijm, Ingrid, Danser, A H Jan, Roks, Anton J M
Published in Clinical science (1979) (01.08.2017)
Published in Clinical science (1979) (01.08.2017)
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Maximum renal responses to renin inhibition in healthy study participants: VTP-27999 versus aliskiren
Barkoudah, Ebrahim, van Thiel, Bibi S, Fisher, Naomi D L, Gregg, Richard A, Danser, A H Jan, Moukarbel, George V, Hollenberg, Norman K
Published in Journal of hypertension (01.05.2016)
Published in Journal of hypertension (01.05.2016)
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On the origin of brain renin
Danser, Alexander H, van Thiel, Bibi S, Riet, Luuk te, Severs, David, Uil, Estrellita, Garrelds, Ingrid M, Alenina, Natalia, Qadri, Fatimunnisa, Bader, Michael
Published in Journal of the American Society of Hypertension (01.04.2016)
Published in Journal of the American Society of Hypertension (01.04.2016)
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Journal Article
DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice
Boer, Martine, Lintel Hekkert, Maaike, Chang, Jiang, Thiel, Bibi S., Martens, Leonie, Bos, Maxime M., Kleijnen, Marion G. J., Ridwan, Yanto, Octavia, Yanti, Deel, Elza D., Blonden, Lau A., Brandt, Renata M. C., Barnhoorn, Sander, Bautista‐Niño, Paula K., Krabbendam‐Peters, Ilona, Wolswinkel, Rianne, Arshi, Banafsheh, Ghanbari, Mohsen, Kupatt, Christian, Windt, Leon J., Danser, A. H. Jan, Pluijm, Ingrid, Remme, Carol Ann, Stoll, Monika, Pothof, Joris, Roks, Anton J. M., Kavousi, Maryam, Essers, Jeroen, Velden, Jolanda, Hoeijmakers, Jan H. J., Duncker, Dirk J.
Published in Aging cell (01.03.2023)
Published in Aging cell (01.03.2023)
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Abstract P278: On the Origin of Brain Renin
van Thiel, Bibi S, te Riet, Luuk, Severs, David, Uijl, Estrellita, Garrelds, Ingrid M, Qadri, Fatimunnisa, Alenina, Natalia, Bader, Michael, Danser, A
Published in Hypertension (Dallas, Tex. 1979) (01.09.2016)
Published in Hypertension (Dallas, Tex. 1979) (01.09.2016)
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Journal Article
Abstract 15335: Hybrid Optical and CT Imaging Reveals Increased Matrix Metalloprotease Activity and Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice
van Thiel, Bibi S, Ridwan, Yanto, de Boer, Martine, de Kleijnen, Marion G.J, van Vliet, Nicole, van Heijningen, Paula M, Vermeij, Wilbert P, Danser, Jan H, Kanaar, Roland, Duncker, Dirk J, Hoeijmakers, Jan H.J, Van Der Pluijm, Ingrid, Essers, Jeroen
Published in Circulation (New York, N.Y.) (19.11.2019)
Published in Circulation (New York, N.Y.) (19.11.2019)
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Journal Article
Folate Receptor-Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?
Winkel, Leah C J, Groen, Harald C, van Thiel, Bibi S, Müller, Cristina, van der Steen, Antonius F W, Wentzel, Jolanda J, de Jong, Marion, Van der Heiden, Kim
Published in Molecular imaging (01.01.2014)
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Published in Molecular imaging (01.01.2014)
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