A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2
Simonis, Alexander, Theobald, Sebastian J, Fätkenheuer, Gerd, Rybniker, Jan, Malin, Jakob J
Published in EMBO molecular medicine (11.01.2021)
Published in EMBO molecular medicine (11.01.2021)
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RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling
Knopf, Julia D, Steigleder, Susanne S, Korn, Friederike, Kühnle, Nathalie, Badenes, Marina, Tauber, Marina, Theobald, Sebastian J, Rybniker, Jan, Adrain, Colin, Lemberg, Marius K
Published in Nature communications (07.03.2024)
Published in Nature communications (07.03.2024)
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Journal Article
Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
Eisfeld, Hannah S., Simonis, Alexander, Winter, Sandra, Chhen, Jason, Ströh, Luisa J., Krey, Thomas, Koch, Manuel, Theobald, Sebastian J., Rybniker, Jan
Published in Viruses (15.10.2021)
Published in Viruses (15.10.2021)
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Journal Article
Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV
Theobald, Sebastian J, Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija, Ballmaier, Matthias, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, Kaisenberg, Constantin von, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian, Stripecke, Renata
Published in PLoS pathogens (15.07.2020)
Published in PLoS pathogens (15.07.2020)
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Journal Article
Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS‐CoV‐2 mRNA vaccination
Theobald, Sebastian J, Simonis, Alexander, Mudler, Julie M, Göbel, Ulrike, Acton, Richard, Kohlhas, Viktoria, Albert, Marie‐Christine, Hellmann, Anna‐Maria, Malin, Jakob J, Winter, Sandra, Hallek, Michael, Walczak, Henning, Nguyen, Phuong‐Hien, Koch, Manuel, Rybniker, Jan
Published in EMBO molecular medicine (08.08.2022)
Published in EMBO molecular medicine (08.08.2022)
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PD-1 Blockade Aggravates Epstein-Barr Virus + Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4 + T Cell Dysregulations
Volk, Valery, Theobald, Sebastian J, Danisch, Simon, Khailaie, Sahamoddin, Kalbarczyk, Maja, Schneider, Andreas, Bialek-Waldmann, Julia, Krönke, Nicole, Deng, Yun, Eiz-Vesper, Britta, Dragon, Anna Christina, von Kaisenberg, Constantin, Lienenklaus, Stefan, Bleich, Andre, Keck, James, Meyer-Hermann, Michael, Klawonn, Frank, Hammerschmidt, Wolfgang, Delecluse, Henri-Jacques, Münz, Christian, Feuerhake, Friedrich, Stripecke, Renata
Published in Frontiers in oncology (12.01.2021)
Published in Frontiers in oncology (12.01.2021)
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Journal Article
Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV
Theobald, Sebastian J, Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija, Ballmaier, Matthias, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, von Kaisenberg, Constantin, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian, Stripecke, Renata
Published in PLoS pathogens (01.03.2021)
Published in PLoS pathogens (01.03.2021)
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Journal Article
CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease
Slabik, Constanze, Kalbarczyk, Maja, Danisch, Simon, Zeidler, Reinhard, Klawonn, Frank, Volk, Valery, Krönke, Nicole, Feuerhake, Friedrich, Ferreira de Figueiredo, Constanca, Blasczyk, Rainer, Olbrich, Henning, Theobald, Sebastian J., Schneider, Andreas, Ganser, Arnold, von Kaisenberg, Constantin, Lienenklaus, Stefan, Bleich, Andre, Hammerschmidt, Wolfgang, Stripecke, Renata
Published in Molecular therapy. Oncolytics (25.09.2020)
Published in Molecular therapy. Oncolytics (25.09.2020)
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Journal Article
Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34 + Cells
Theobald, Sebastian J, Khailaie, Sahamoddin, Meyer-Hermann, Michael, Volk, Valery, Olbrich, Henning, Danisch, Simon, Gerasch, Laura, Schneider, Andreas, Sinzger, Christian, Schaudien, Dirk, Lienenklaus, Stefan, Riese, Peggy, Guzman, Carlos A, Figueiredo, Constanca, von Kaisenberg, Constantin, Spineli, Loukia M, Glaesener, Stephanie, Meyer-Bahlburg, Almut, Ganser, Arnold, Schmitt, Michael, Mach, Michael, Messerle, Martin, Stripecke, Renata
Published in Frontiers in immunology (22.11.2018)
Published in Frontiers in immunology (22.11.2018)
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Journal Article
Fully Human Herpesvirus-Specific Neutralizing IgG Antibodies Generated by EBV Immortalization of Splenocytes-Derived from Immunized Humanized Mice
Theobald, Sebastian J, Fiestas, Elena, Schneider, Andreas, Ostermann, Benjamin, Danisch, Simon, von Kaisenberg, Constantin, Rybniker, Jan, Hammerschmidt, Wolfgang, Zeidler, Reinhard, Stripecke, Renata
Published in Cells (Basel, Switzerland) (21.12.2023)
Published in Cells (Basel, Switzerland) (21.12.2023)
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Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization
Volk, Valery, Reppas, Andreas I, Robert, Philippe A, Spineli, Loukia M, Sundarasetty, Bala Sai, Theobald, Sebastian J, Schneider, Andreas, Gerasch, Laura, Deves Roth, Candida, Klöss, Stephan, Koehl, Ulrike, von Kaisenberg, Constantin, Figueiredo, Constanca, Hatzikirou, Haralampos, Meyer-Hermann, Michael, Stripecke, Renata
Published in Frontiers in immunology (08.12.2017)
Published in Frontiers in immunology (08.12.2017)
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Immunological fingerprint in coronavirus disease-19 convalescents with and without post-COVID syndrome
Augustin, Max, Heyn, Ferdinand, Ullrich, Stella, Sandaradura de Silva, Ute, Albert, Marie-Christine, Linne, Viktoria, Schlotz, Maike, Schommers, Philipp, Pracht, Elisabeth, Horn, Carola, Suarez, Isabelle, Simonis, Alexander, Picard, Lea Katharina, Zoufaly, Alexander, Wenisch, Christoph, Fätkenheuer, Gerd, Gruell, Henning, Klein, Florian, Hallek, Michael, Walczak, Henning, Rybniker, Jan, Theobald, Sebastian J, Lehmann, Clara
Published in Frontiers in medicine (24.04.2023)
Published in Frontiers in medicine (24.04.2023)
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Journal Article
Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
Theobald, Sebastian J., Gräb, Jessica, Fritsch, Melanie, Suárez, Isabelle, Eisfeld, Hannah S., Winter, Sandra, Koch, Maximilian, Hölscher, Christoph, Pasparakis, Manolis, Kashkar, Hamid, Rybniker, Jan
Published in Cell death discovery (30.10.2021)
Published in Cell death discovery (30.10.2021)
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In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution
Kumar, Suresh, Koenig, Johannes, Schneider, Andreas, Wermeling, Fredrik, Boddul, Sanjaykumar, Theobald, Sebastian J., Vollmer, Miriam, Kloos, Doreen, Lachmann, Nico, Klawonn, Frank, Lienenklaus, Stefan, Talbot, Steven R., Bleich, André, Wenzel, Nadine, von Kaisenberg, Constantin, Keck, James, Stripecke, Renata
Published in Biomedicines (05.08.2021)
Published in Biomedicines (05.08.2021)
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Journal Article
Effect of cryopreservation on lymph node fragment regeneration after autologous transplantation in the minipig model
Hadamitzky, Catarina, Perić, Hanes, Theobald, Sebastian J., Gratz, Klaus Friedrich, Spohr, Hendrik, Pabst, Reinhard, Vogt, Peter M.
Published in Innovative surgical sciences (01.06.2018)
Published in Innovative surgical sciences (01.06.2018)
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Journal Article
Adult and Cord Blood-Derived High-Affinity gB-CAR-T Cells Effectively React Against Human Cytomegalovirus Infections
Olbrich, Henning, Theobald, Sebastian J, Slabik, Constanze, Gerasch, Laura, Schneider, Andreas, Mach, Michael, Shum, Thomas, Mamonkin, Maksim, Stripecke, Renata
Published in Human gene therapy (01.04.2020)
Published in Human gene therapy (01.04.2020)
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Journal Article
Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19
Theobald, Sebastian J, Simonis, Alexander, Georgomanolis, Theodoros, Kreer, Christoph, Zehner, Matthias, Eisfeld, Hannah S, Albert, Marie‐Christine, Chhen, Jason, Motameny, Susanne, Erger, Florian, Fischer, Julia, Malin, Jakob J, Gräb, Jessica, Winter, Sandra, Pouikli, Andromachi, David, Friederike, Böll, Boris, Koehler, Philipp, Vanshylla, Kanika, Gruell, Henning, Suárez, Isabelle, Hallek, Michael, Fätkenheuer, Gerd, Jung, Norma, Cornely, Oliver A, Lehmann, Clara, Tessarz, Peter, Altmüller, Janine, Nürnberg, Peter, Kashkar, Hamid, Klein, Florian, Koch, Manuel, Rybniker, Jan
Published in EMBO molecular medicine (09.08.2021)
Published in EMBO molecular medicine (09.08.2021)
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Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system
Gries, Raphael, Chhen, Jason, van Gumpel, Edeltraud, Theobald, Sebastian J., Sonnenkalb, Lindsay, Utpatel, Christian, Metzen, Fabian, Koch, Manuel, Dallenga, Tobias, Djaout, Kamel, Baulard, Alain, Dal Molin, Michael, Rybniker, Jan
Published in Cell chemical biology (18.04.2024)
Published in Cell chemical biology (18.04.2024)
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Journal Article
The role of inflammasomes as central inflammatory hubs in Mycobacterium tuberculosis infection
Theobald, Sebastian J., Müller, Tony A., Lange, Dinah, Keck, Katharina, Rybniker, Jan
Published in Frontiers in immunology (11.09.2024)
Published in Frontiers in immunology (11.09.2024)
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Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
Simonis, Alexander, Kreer, Christoph, Albus, Alexandra, Rox, Katharina, Yuan, Biao, Holzmann, Dmitriy, Wilms, Joana A, Zuber, Sylvia, Kottege, Lisa, Winter, Sandra, Meyer, Meike, Schmitt, Kristin, Gruell, Henning, Theobald, Sebastian J, Hellmann, Anna-Maria, Meyer, Christina, Ercanoglu, Meryem Seda, Cramer, Nina, Munder, Antje, Hallek, Michael, Fätkenheuer, Gerd, Koch, Manuel, Seifert, Harald, Rietschel, Ernst, Marlovits, Thomas C, van Koningsbruggen-Rietschel, Silke, Klein, Florian, Rybniker, Jan
Published in Cell (09.11.2023)
Published in Cell (09.11.2023)
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