Lipodox® (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx® (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models
Burade, Vinod, Bhowmick, Subhas, Maiti, Kuntal, Zalawadia, Rishit, Ruan, Harry, Thennati, Rajamannar
Published in BMC cancer (06.06.2017)
Published in BMC cancer (06.06.2017)
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Therapeutic efficacies of mitochondria-targeted esculetin and metformin in the improvement of age-associated atherosclerosis via regulating AMPK activation
Pulipaka, Sriravali, Singuru, Gajalakshmi, Sahoo, Shashikanta, Shaikh, Altab, Thennati, Rajamannar, Kotamraju, Srigiridhar
Published in GeroScience (01.04.2024)
Published in GeroScience (01.04.2024)
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In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist
Jones, Ben, Burade, Vinod, Akalestou, Elina, Manchanda, Yusman, Ramchunder, Zenouska, Carrat, Gaëlle, Nguyen‐Tu, Marie‐Sophie, Marchetti, Piero, Piemonti, Lorenzo, Leclerc, Isabelle, Thennati, Rajamannar, Vilsboll, Tina, Thorens, Bernard, Tomas, Alejandra, Rutter, Guy A.
Published in Diabetes, obesity & metabolism (01.11.2022)
Published in Diabetes, obesity & metabolism (01.11.2022)
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Correction to: Therapeutic efficacies of mitochondria‑targeted esculetin and metformin in the improvement of age‑associated atherosclerosis via regulating AMPK activation
Pulipaka, Sriravali, Singuru, Gajalakshmi, Sahoo, Shashikanta, Shaikh, Altab, Thennati, Rajamannar, Kotamraju, Srigiridhar
Published in GeroScience (01.04.2024)
Published in GeroScience (01.04.2024)
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Journal Article
Comparison of Physicochemical Properties of Generic Doxorubicin HCl Liposome Injection with the Reference Listed Drug
Maiti, Kuntal, Bhowmick, Subhas, Jain, Pankaj, Zope, Murlidhar, Doshi, Keyur, Rajamannar, Thennati
Published in Anti-cancer agents in medicinal chemistry (2018)
Published in Anti-cancer agents in medicinal chemistry (2018)
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A GLP-1 Receptor Agonist, GL0034, Improves Liver Function in Diet Induced-Obesity Mouse Model
Thennati, Rajamannar, Burade, Vinod, Rutter, Guy, Vilsbøll, Tina, Thorens, Bernard
Published in Obesity (Silver Spring, Md.) (01.11.2022)
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Published in Obesity (Silver Spring, Md.) (01.11.2022)
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Mitochondria-targeted esculetin mitigates atherosclerosis in the setting of aging via the modulation of SIRT1-mediated vascular cell senescence and mitochondrial function in Apoe−/− mice
Karnewar, Santosh, Pulipaka, Sriravali, Katta, Sujana, Panuganti, Devayani, Neeli, Praveen Kumar, Thennati, Rajamannar, Jerald, Mahesh Kumar, Kotamraju, Srigiridhar
Published in Atherosclerosis (01.09.2022)
Published in Atherosclerosis (01.09.2022)
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Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice
Singuru, Gajalakshmi, Pulipaka, Sriravali, Shaikh, Altab, Sahoo, Shashikanta, Jangam, Aruna, Thennati, Rajamannar, Kotamraju, Srigiridhar
Published in Journal of molecular medicine (Berlin, Germany) (01.07.2024)
Published in Journal of molecular medicine (Berlin, Germany) (01.07.2024)
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Mitochondria-targeted esculetin and metformin delay endothelial senescence by promoting fatty acid β-oxidation: Relevance in age-associated atherosclerosis
Pulipaka, Sriravali, Chempon, Hridya, Singuru, Gajalakshmi, Sahoo, Shashikanta, Shaikh, Altab, Kumari, Sunita, Thennati, Rajamannar, Kotamraju, Srigiridhar
Published in Mechanisms of ageing and development (01.06.2024)
Published in Mechanisms of ageing and development (01.06.2024)
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116-OR: GL0034 (Utreglutide), a Novel GLP-1RA, Increases Liver FGF-21 and Demonstrates Significant Efficacy on Weight Loss, HbA1c, and Triglycerides in db/db Mice
Thennati, Rajamannar, Burade, Vinod S, Natarajan, Muthukumaran, Garcia-Ocana, Adolfo, Rutter, Guy A, Pratley, Richard E, Thorens, Bernard, Vilsbøll, Tina
Published in Diabetes (New York, N.Y.) (01.06.2024)
Published in Diabetes (New York, N.Y.) (01.06.2024)
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Therapeutic efficacy of mitochondria-targeted esculetin in the improvement of NAFLD-NASH via modulating AMPK-SIRT1 axis
Singuru, Gajalakshmi, Pulipaka, Sriravali, Shaikh, Altab, Balaji Andugulapati, Sai, Thennati, Rajamannar, Kotamraju, Srigiridhar
Published in International immunopharmacology (01.11.2023)
Published in International immunopharmacology (01.11.2023)
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GL0034, A novel long-acting glucagon-like peptide 1 receptor agonist exhibits significant efficacy in aged db/db mouse model of non-alcoholic fatty liver disease (NAFLD)
Thennati, Rajamannar, Burade, Vinod, Garcia-Ocana, Adolfo, Pratley, Richard E, Rutter, Guy, Vilsbøll, Tina, Thorens, Bernard
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Two multicenter Phase I randomized trials to compare the bioequivalence and safety of a generic doxorubicin hydrochloride liposome injection with Doxil® or Caelyx® in advanced ovarian cancer
Bhowmik, Shravanti, Bhowmick, Subhas, Maiti, Kuntal, Chakra, Amaresh, Shahi, Pradeep, Jain, Deepak, Rajamannar, Thennati
Published in Cancer chemotherapy and pharmacology (01.09.2018)
Published in Cancer chemotherapy and pharmacology (01.09.2018)
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SAT-231 GL0034 (Utreglutide), a long acting, glucagon-like peptide-1 receptor agonist, improves body weight loss, lipid and liver injury markers in individuals with obesity: A phase 1 multiple ascending dose study
Thennati, Rajamannar, Burade, Vinod, Natarajan, Muthukumaran, Shahi, Pradeep, Nagaraja, Ravishankara, Agrawal, Sudeep, Jandrain, Bernard, Duvauchelle, Thierry, Pratley, Richard E., Thorens, Bernard, Vilsbøll, Tina, Loomba, Rohit
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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GL0034 (Utreglutide), a novel, long acting, glucagon-like peptide 1 receptor agonist (GLP-1 RA), results of a phase 1 study in healthy individuals
Thennati, Rajamannar, Burade, Vinod, Natarajan, Muthukumaran, Shahi, Pradeep, Nagaraja, Ravishankara, Panchal, Satish, Agrawal, Sudeep, Jandrain, Bernard, Duvauchelle, Thierry, Pratley, Richard E., Thorens, Bernard, Vilsbøll, Tina
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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THU-419 - GL0034 (Utreglutide), a novel, long acting, glucagon-like peptide 1 receptor agonist (GLP-1 RA), results of a phase 1 study in healthy individuals
Thennati, Rajamannar, Burade, Vinod, Natarajan, Muthukumaran, Shahi, Pradeep, Nagaraja, Ravishankara, Panchal, Satish, Agrawal, Sudeep, Jandrain, Bernard, Duvauchelle, Thierry, Pratley, Richard E., Thorens, Bernard, Vilsbøll, Tina
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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121-OR: Safety, Tolerability, and Metabolic Effects of Once-Weekly GL0034 (Utreglutide) in Individuals with Obesity—A Multiple Ascending Dose Study
THENNATI, RAJAMANNAR, BURADE, VINOD S., NATARAJAN, MUTHUKUMARAN, SHAHI, PRADEEP, NAGARAJA, RAVISHANKARA, AGRAWAL, SUDEEP K., DUVAUCHELLE, THIERRY, GARCIA-OCANA, ADOLFO, RUTTER, GUY A., PRATLEY, RICHARD E., THORENS, BERNARD, VILSBØLL, TINA
Published in Diabetes (New York, N.Y.) (14.06.2024)
Published in Diabetes (New York, N.Y.) (14.06.2024)
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A functional and self-assembling octyl-phosphonium-tagged esculetin as an effective siRNA delivery agent
Shaikh, Altab, Neeli, Praveen Kumar, Singuru, Gajalakshmi, Panangipalli, Sravya, Banerjee, Rajkumar, Maddi, Sridhar Reddy, Thennati, Rajamannar, Bathula, Surendar Reddy, Kotamraju, Srigiridhar
Published in Chemical communications (Cambridge, England) (19.11.2021)
Published in Chemical communications (Cambridge, England) (19.11.2021)
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Allergic rhinitis: An update on disease, present treatments and future prospects
Mandhane, Sanjay N., Shah, Jigar H., Thennati, Rajamannar
Published in International immunopharmacology (01.11.2011)
Published in International immunopharmacology (01.11.2011)
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