Whole-genome sequencing of patients with rare diseases in a national health system
Turro, Ernest, Astle, William J., Megy, Karyn, Gräf, Stefan, Greene, Daniel, Shamardina, Olga, Allen, Hana Lango, Sanchis-Juan, Alba, Frontini, Mattia, Thys, Chantal, Stephens, Jonathan, Mapeta, Rutendo, Burren, Oliver S., Downes, Kate, Haimel, Matthias, Tuna, Salih, Deevi, Sri V. V., Aitman, Timothy J., Bennett, David L., Calleja, Paul, Carss, Keren, Caulfield, Mark J., Chinnery, Patrick F., Dixon, Peter H., Gale, Daniel P., James, Roger, Koziell, Ania, Laffan, Michael A., Levine, Adam P., Maher, Eamonn R., Markus, Hugh S., Morales, Joannella, Morrell, Nicholas W., Mumford, Andrew D., Ormondroyd, Elizabeth, Rankin, Stuart, Rendon, Augusto, Richardson, Sylvia, Roberts, Irene, Roy, Noemi B. A., Saleem, Moin A., Smith, Kenneth G. C., Stark, Hannah, Tan, Rhea Y. Y., Themistocleous, Andreas C., Thrasher, Adrian J., Watkins, Hugh, Webster, Andrew R., Wilkins, Martin R., Williamson, Catherine, Whitworth, James, Humphray, Sean, Bentley, David R., Kingston, Nathalie, Walker, Neil, Bradley, John R., Ashford, Sofie, Penkett, Christopher J., Freson, Kathleen, Stirrups, Kathleen E., Raymond, F. Lucy, Ouwehand, Willem H.
Published in Nature (London) (02.07.2020)
Published in Nature (London) (02.07.2020)
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Journal Article
Using stratified medicine to understand, diagnose, and treat neuropathic pain
Themistocleous, Andreas C., Crombez, Geert, Baskozos, Georgios, Bennett, David L.
Published in Pain (Amsterdam) (01.09.2018)
Published in Pain (Amsterdam) (01.09.2018)
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Journal Article
Nav1.7 is required for normal C-low threshold mechanoreceptor function in humans and mice
Middleton, Steven J, Perini, Irene, Themistocleous, Andreas C, Weir, Greg A, McCann, Kirsty, Barry, Allison M, Marshall, Andrew, Lee, Michael, Mayo, Leah M, Bohic, Manon, Baskozos, Georgios, Morrison, India, Löken, Line S, McIntyre, Sarah, Nagi, Saad S, Staud, Roland, Sehlstedt, Isac, Johnson, Richard D, Wessberg, Johan, Wood, John N, Woods, Christopher G, Moqrich, Aziz, Olausson, Håkan, Bennett, David L
Published in Brain (London, England : 1878) (21.10.2022)
Published in Brain (London, England : 1878) (21.10.2022)
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Journal Article
Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies
Auer-Grumbach, Michaela, Toegel, Stefan, Schabhüttl, Maria, Weinmann, Daniela, Chiari, Catharina, Bennett, David L.H., Beetz, Christian, Klein, Dennis, Andersen, Peter M., Böhme, Ilka, Fink-Puches, Regina, Gonzalez, Michael, Harms, Matthew B., Motley, William, Reilly, Mary M., Renner, Wilfried, Rudnik-Schöneborn, Sabine, Schlotter-Weigel, Beate, Themistocleous, Andreas C., Weishaupt, Jochen H., Ludolph, Albert C., Wieland, Thomas, Tao, Feifei, Abreu, Lisa, Windhager, Reinhard, Zitzelsberger, Manuela, Strom, Tim M., Walther, Thomas, Scherer, Steven S., Züchner, Stephan, Martini, Rudolf, Senderek, Jan
Published in American journal of human genetics (01.09.2016)
Published in American journal of human genetics (01.09.2016)
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Journal Article
Defining the Functional Role of Na V 1.7 in Human Nociception
McDermott, Lucy A, Weir, Greg A, Themistocleous, Andreas C, Segerdahl, Andrew R, Blesneac, Iulia, Baskozos, Georgios, Clark, Alex J, Millar, Val, Peck, Liam J, Ebner, Daniel, Tracey, Irene, Serra, Jordi, Bennett, David L
Published in Neuron (Cambridge, Mass.) (06.03.2019)
Published in Neuron (Cambridge, Mass.) (06.03.2019)
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Journal Article
Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management
Jensen, Troels S, Karlsson, Pall, Gylfadottir, Sandra S, Andersen, Signe T, Bennett, David L, Tankisi, Hatice, Finnerup, Nanna B, Terkelsen, Astrid J, Khan, Karolina, Themistocleous, Andreas C, Kristensen, Alexander G, Itani, Mustapha, Sindrup, Søren H, Andersen, Henning, Charles, Morten, Feldman, Eva L, Callaghan, Brian C
Published in Brain (London, England : 1878) (28.07.2021)
Published in Brain (London, England : 1878) (28.07.2021)
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Journal Article
Defining the Functional Role of NaV1.7 in Human Nociception
McDermott, Lucy A., Weir, Greg A., Themistocleous, Andreas C., Segerdahl, Andrew R., Blesneac, Iulia, Baskozos, Georgios, Clark, Alex J., Millar, Val, Peck, Liam J., Ebner, Daniel, Tracey, Irene, Serra, Jordi, Bennett, David L.
Published in Neuron (Cambridge, Mass.) (06.03.2019)
Published in Neuron (Cambridge, Mass.) (06.03.2019)
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Journal Article
Studying human nociceptors: from fundamentals to clinic
Middleton, Steven J, Barry, Allison M, Comini, Maddalena, Li, Yan, Ray, Pradipta R, Shiers, Stephanie, Themistocleous, Andreas C, Uhelski, Megan L, Yang, Xun, Dougherty, Patrick M, Price, Theodore J, Bennett, David L
Published in Brain (London, England : 1878) (22.06.2021)
Published in Brain (London, England : 1878) (22.06.2021)
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Journal Article
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
Dawes, John M., Weir, Greg A., Middleton, Steven J., Patel, Ryan, Chisholm, Kim I., Pettingill, Philippa, Peck, Liam J., Sheridan, Joseph, Shakir, Akila, Jacobson, Leslie, Gutierrez-Mecinas, Maria, Galino, Jorge, Walcher, Jan, Kühnemund, Johannes, Kuehn, Hannah, Sanna, Maria D., Lang, Bethan, Clark, Alex J., Themistocleous, Andreas C., Iwagaki, Noboru, West, Steven J., Werynska, Karolina, Carroll, Liam, Trendafilova, Teodora, Menassa, David A., Giannoccaro, Maria Pia, Coutinho, Ester, Cervellini, Ilaria, Tewari, Damini, Buckley, Camilla, Leite, M. Isabel, Wildner, Hendrik, Zeilhofer, Hanns Ulrich, Peles, Elior, Todd, Andrew J., McMahon, Stephen B., Dickenson, Anthony H., Lewin, Gary R., Vincent, Angela, Bennett, David L.
Published in Neuron (Cambridge, Mass.) (21.02.2018)
Published in Neuron (Cambridge, Mass.) (21.02.2018)
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Journal Article
The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy
Themistocleous, Andreas C., Ramirez, Juan D., Shillo, Pallai R., Lees, Jonathan G., Selvarajah, Dinesh, Orengo, Christine, Tesfaye, Solomon, Rice, Andrew S.C., Bennett, David L.H.
Published in Pain (Amsterdam) (01.05.2016)
Published in Pain (Amsterdam) (01.05.2016)
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Journal Article
Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy
Blesneac, Iulia, Themistocleous, Andreas C., Fratter, Carl, Conrad, Linus J., Ramirez, Juan D., Cox, James J., Tesfaye, Solomon, Shillo, Pallai R., Rice, Andrew S.C., Tucker, Stephen J., Bennett, David L.H.
Published in Pain (Amsterdam) (01.03.2018)
Published in Pain (Amsterdam) (01.03.2018)
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Journal Article
Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy
Vale, Tom A, Symmonds, Mkael, Polydefkis, Michael, Byrnes, Kelly, Rice, Andrew S C, Themistocleous, Andreas C, Bennett, David L H
Published in Brain (London, England : 1878) (01.10.2017)
Published in Brain (London, England : 1878) (01.10.2017)
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Journal Article
Transcriptional regulator PRDM12 is essential for human pain perception
Chen, Ya-Chun, Auer-Grumbach, Michaela, Matsukawa, Shinya, Zitzelsberger, Manuela, Themistocleous, Andreas C, Strom, Tim M, Samara, Chrysanthi, Moore, Adrian W, Cho, Lily Ting-Yin, Young, Gareth T, Weiss, Caecilia, Schabhüttl, Maria, Stucka, Rolf, Schmid, Annina B, Parman, Yesim, Graul-Neumann, Luitgard, Heinritz, Wolfram, Passarge, Eberhard, Watson, Rosemarie M, Hertz, Jens Michael, Moog, Ute, Baumgartner, Manuela, Valente, Enza Maria, Pereira, Diego, Restrepo, Carlos M, Katona, Istvan, Dusl, Marina, Stendel, Claudia, Wieland, Thomas, Stafford, Fay, Reimann, Frank, von Au, Katja, Finke, Christian, Willems, Patrick J, Nahorski, Michael S, Shaikh, Samiha S, Carvalho, Ofélia P, Nicholas, Adeline K, Karbani, Gulshan, McAleer, Maeve A, Cilio, Maria Roberta, McHugh, John C, Murphy, Sinead M, Irvine, Alan D, Jensen, Uffe Birk, Windhager, Reinhard, Weis, Joachim, Bergmann, Carsten, Rautenstrauss, Bernd, Baets, Jonathan, De Jonghe, Peter, Reilly, Mary M, Kropatsch, Regina, Kurth, Ingo, Chrast, Roman, Michiue, Tatsuo, Bennett, David L H, Woods, C Geoffrey, Senderek, Jan
Published in Nature genetics (01.07.2015)
Published in Nature genetics (01.07.2015)
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Journal Article
Leucine‐Rich Glioma‐Inactivated 1 versus Contactin‐Associated Protein‐like 2 Antibody Neuropathic Pain: Clinical and Biological Comparisons
Ramanathan, Sudarshini, Tseng, Mandy, Davies, Alexander J., Uy, Christopher E., Paneva, Sofija, Mgbachi, Victor C., Michael, Sophia, Varley, James A., Binks, Sophie, Themistocleous, Andreas C., Fehmi, Janev, Anziska, Yaacov, Soni, Anushka, Hofer, Monika, Waters, Patrick, Brilot, Fabienne, Dale, Russell C., Dawes, John, Rinaldi, Simon, Bennett, David L., Irani, Sarosh R.
Published in Annals of neurology (01.10.2021)
Published in Annals of neurology (01.10.2021)
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Journal Article
Cold aggravates abnormal excitability of motor axons in oxaliplatin‐treated patients
Bennedsgaard, Kristine, Ventzel, Lise, Grafe, Peter, Tigerholm, Jenny, Themistocleous, Andreas C., Bennett, David L., Tankisi, Hatice, Finnerup, Nanna B.
Published in Muscle & nerve (01.06.2020)
Published in Muscle & nerve (01.06.2020)
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Journal Article
Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations
Vollert, Jan, Maier, Christoph, Attal, Nadine, Bennett, David L.H., Bouhassira, Didier, Enax-Krumova, Elena K., Finnerup, Nanna B., Freynhagen, Rainer, Gierthmühlen, Janne, Haanpää, Maija, Hansson, Per, Hüllemann, Philipp, Jensen, Troels S., Magerl, Walter, Ramirez, Juan D., Rice, Andrew S.C., Schuh-Hofer, Sigrid, Segerdahl, Märta, Serra, Jordi, Shillo, Pallai R., Sindrup, Soeren, Tesfaye, Solomon, Themistocleous, Andreas C., Tölle, Thomas R., Treede, Rolf-Detlef, Baron, Ralf
Published in Pain (Amsterdam) (01.08.2017)
Published in Pain (Amsterdam) (01.08.2017)
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Journal Article
Oxaliplatin‐ and docetaxel‐induced polyneuropathy: clinical and neurophysiological characteristics
Bennedsgaard, Kristine, Ventzel, Lise, Andersen, Niels T., Themistocleous, Andreas C., Bennett, David L., Jensen, Troels S., Tankisi, Hatice, Finnerup, Nanna B.
Published in Journal of the peripheral nervous system (01.12.2020)
Published in Journal of the peripheral nervous system (01.12.2020)
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Journal Article
What is associated with painful polyneuropathy? A cross-sectional analysis of symptoms and signs in patients with painful and painless polyneuropathy
Gierthmühlen, Janne, Attal, Nadine, Baskozos, Georgios, Bennedsgaard, Kristine, Bennett, David L, Bouhassira, Didier, Crombez, Geert, Finnerup, Nanna B, Granovsky, Yelena, Jensen, Troels Staehelin, John, Jishi, Kennes, Lieven Nils, Laycock, Helen, Pascal, Mathilde M V, Rice, Andrew S C, Shafran-Topaz, Leah, Themistocleous, Andreas C, Yarnitsky, David, Baron, Ralf
Published in Pain (Amsterdam) (01.12.2024)
Published in Pain (Amsterdam) (01.12.2024)
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