The performance of a Bayesian value-based sequential clinical trial design in the presence of an equivocal cost-effectiveness signal: evidence from the HERO trial
Welch, Charlie, Forster, Martin, Ronaldson, Sarah, Keding, Ada, Corbacho-Martín, Belen, Tharmanathan, Puvan
Published in BMC medical research methodology (19.07.2024)
Published in BMC medical research methodology (19.07.2024)
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Journal Article
A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial
Littlewood, Elizabeth, Duarte, Ana, Hewitt, Catherine, Knowles, Sarah, Palmer, Stephen, Walker, Simon, Andersen, Phil, Araya, Ricardo, Barkham, Michael, Bower, Peter, Brabyn, Sally, Brierley, Gwen, Cooper, Cindy, Gask, Linda, Kessler, David, Lester, Helen, Lovell, Karina, Muhammad, Usman, Parry, Glenys, Richards, David A, Richardson, Rachel, Tallon, Debbie, Tharmanathan, Puvan, White, David, Gilbody, Simon
Published in Health technology assessment (Winchester, England) (01.12.2015)
Published in Health technology assessment (Winchester, England) (01.12.2015)
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Journal Article
Biomarker Driven Antifungal Stewardship (BioDriveAFS) in acute leukaemia-a multi-centre randomised controlled trial to assess clinical and cost effectiveness: a study protocol for a randomised controlled trial
Flett, Lydia, Abdelatif, Radwa, Baz, Sarah Akhtar, Brady, Samantha, Corbacho, Belén, Common, Kate, Cowling, Abbie, Fairhurst, Caroline, Fitzmaurice, Ellie, Gandhi, Shreyans, Hilton, Andrea, Hope, William, Howard, Alex, Laycock, Joanne, Lillie, Patrick, Mitchell, Gemma, Parker, Adwoa, Peel, Mary, Sheard, Laura, Sneddon, Jacqueline, Taynton, Thomas, Tharmanathan, Puvan, Torgerson, David, Wang, Han-I, Allsup, David, Barlow, Gavin
Published in Current controlled trials in cardiovascular medicine (28.06.2024)
Published in Current controlled trials in cardiovascular medicine (28.06.2024)
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Journal Article
Reverse shoulder arthroplasty versus hemiarthroplasty versus non-surgical treatment for older adults with acute 3- or 4-part fractures of the proximal humerus: study protocol for a randomised controlled trial (PROFHER-2: PROximal Fracture of Humerus Evaluation by Randomisation - Trial Number 2)
Rangan, Amar, Gwilym, Stephen, Keding, Ada, Corbacho, Belen, Kottam, Lucksy, Arundel, Catherine, Coleman, Elizabeth, DiMascio, Livio, Hewitt, Catherine, Jones, Valerie, Kassam, Jamila, McDaid, Catriona, Mitchell, Natasha, Mott, Andrew, O'Carroll, Grace, Tharmanathan, Puvan, Torgerson, David
Published in Current controlled trials in cardiovascular medicine (13.04.2023)
Published in Current controlled trials in cardiovascular medicine (13.04.2023)
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Journal Article
Cost-effectiveness of hydroxychloroquine versus placebo for hand osteoarthritis: economic evaluation of the HERO trial [version 1; peer review: 2 approved]
Ronaldson, Sarah J, Keding, Ada, Tharmanathan, Puvan, Arundel, Catherine, Kingsbury, Sarah R, Conaghan, Philip G, Torgerson, David J
Published in F1000 research (2021)
Published in F1000 research (2021)
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Journal Article
Dupuytren’s interventions surgery versus collagenase (DISC) trial: study protocol for a pragmatic, two-arm parallel-group, non-inferiority randomised controlled trial
Dias, Joseph, Arundel, Catherine, Tharmanathan, Puvan, Keding, Ada, Welch, Charlie, Corbacho, Belen, Armaou, Maria, Leighton, Paul, Bainbridge, Christopher, Craigen, Michael, Flett, Lydia, Gascoyne, Samantha, Hewitt, Catherine, James, Elaine, James, Sophie, Johnson, Nick, Jones, Judy, Knowlson, Catherine, Radia, Priya, Torgerson, David, Warwick, David, Watson, Michelle
Published in Current controlled trials in cardiovascular medicine (30.09.2021)
Published in Current controlled trials in cardiovascular medicine (30.09.2021)
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Journal Article
The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias
Tharmanathan, Puvan, Calvert, Melanie, Hampton, John, Freemantle, Nick
Published in BMC medical research methodology (20.03.2008)
Published in BMC medical research methodology (20.03.2008)
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Journal Article
Recruiting ahead of target: What worked in the REEACT trial?
Tharmanathan, Puvan, Brierley, Gwen, Littlewood, Elizabeth, Andersen, Phil, Gilbody, Simon
Published in Current controlled trials in cardiovascular medicine (13.12.2011)
Published in Current controlled trials in cardiovascular medicine (13.12.2011)
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Journal Article
Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial
Gilbody, Simon, Littlewood, Elizabeth, Hewitt, Catherine, Brierley, Gwen, Tharmanathan, Puvan, Araya, Ricardo, Barkham, Michael, Bower, Peter, Cooper, Cindy, Gask, Linda, Kessler, David, Lester, Helen, Lovell, Karina, Parry, Glenys, Richards, David A, Andersen, Phil, Brabyn, Sally, Knowles, Sarah, Shepherd, Charles, Tallon, Debbie, White, David
Published in BMJ (Online) (11.11.2015)
Published in BMJ (Online) (11.11.2015)
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Journal Article
Ongoing validation of health-related quality of life instruments
Cocks, Kim, Tharmanathan, Puvan
Published in Current controlled trials in cardiovascular medicine (16.11.2015)
Published in Current controlled trials in cardiovascular medicine (16.11.2015)
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Journal Article
The current role and perceived benefits and barriers of secondary care pharmacists facilitating patient participation in Clinical Trials of Investigational Medicinal Products (CTIMPs) conducted within the NHS: A cross‐sectional survey
Watson, Michelle, Bewick, Bridgette M., Tharmanathan, Puvan
Published in Journal of evaluation in clinical practice (01.02.2020)
Published in Journal of evaluation in clinical practice (01.02.2020)
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Journal Article
Use and reporting of restricted randomization: a review
Higham, Ruchi, Tharmanathan, Puvan, Birks, Yvonne
Published in Journal of evaluation in clinical practice (01.12.2015)
Published in Journal of evaluation in clinical practice (01.12.2015)
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Journal Article
Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial
Kingsbury, Sarah R, Tharmanathan, Puvan, Keding, Ada, Ronaldson, Sarah J, Grainger, Andrew, Wakefield, Richard J, Arundel, Catherine, Birrell, Fraser, Doherty, Michael, Vincent, Tonia, Watt, Fiona E, Dziedzic, Krysia, O'Neill, Terence W, Arden, Nigel K, Scott, David L, Dickson, John, Garrood, Toby, Green, Michael, Menon, Ajit, Sheeran, Tom, Torgerson, David, Conaghan, Philip G
Published in Annals of internal medicine (20.03.2018)
Published in Annals of internal medicine (20.03.2018)
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Journal Article
Participation in community-based lung cancer screening: the Yorkshire Lung Screening Trial
Crosbie, Philip A J, Gabe, Rhian, Simmonds, Irene, Hancock, Neil, Alexandris, Panos, Kennedy, Martyn, Rogerson, Suzanne, Baldwin, David, Booton, Richard, Bradley, Claire, Darby, Mike, Eckert, Claire, Franks, Kevin N, Lindop, Jason, Janes, Sam M, Møller, Henrik, Murray, Rachael L, Neal, Richard D, Quaife, Samantha L, Upperton, Sara, Shinkins, Bethany, Tharmanathan, Puvan, Callister, Matthew E J
Published in The European respiratory journal (01.11.2022)
Published in The European respiratory journal (01.11.2022)
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Journal Article
Pain Reduction With Oral Methotrexate in Knee Osteoarthritis : A Randomized, Placebo-Controlled Clinical Trial
Kingsbury, Sarah R, Tharmanathan, Puvan, Keding, Ada, Watt, Fiona E, Scott, David L, Roddy, Edward, Birrell, Fraser, Arden, Nigel K, Bowes, Mike, Arundel, Catherine, Watson, Michelle, Ronaldson, Sarah J, Hewitt, Catherine, Doherty, Michael, Moots, Robert J, O'Neill, Terence W, Green, Michael, Patel, Gulam, Garrood, Toby, Edwards, Christopher J, Walmsley, Phil J, Sheeran, Tom, Torgerson, David J, Conaghan, Philip G
Published in Annals of internal medicine (01.09.2024)
Published in Annals of internal medicine (01.09.2024)
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Journal Article
Can learnings from the COVID-19 pandemic improve trial conduct post-pandemic? A case study of strategies used by the DISC trial
Knowlson, Catherine, Tharmanathan, Puvan, Arundel, Catherine, James, Sophie, Flett, Lydia, Gascoyne, Samantha, Welch, Charlie, Warwick, David, Dias, Joseph
Published in Research methods in medicine & health sciences (01.03.2023)
Published in Research methods in medicine & health sciences (01.03.2023)
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Journal Article
Systematic review and mixed treatment comparison of randomized evidence for empirical, pre-emptive and directed treatment strategies for invasive mould disease
Freemantle, Nick, Tharmanathan, Puvan, Herbrecht, Raoul
Published in Journal of antimicrobial chemotherapy (01.01.2011)
Published in Journal of antimicrobial chemotherapy (01.01.2011)
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Journal Article
Analysis of longitudinal oncology quality of life (QoL) data - are we getting it right?
Cocks, Kim, Tharmanathan, Puvan, Smith, Adam
Published in Current controlled trials in cardiovascular medicine (29.11.2013)
Published in Current controlled trials in cardiovascular medicine (29.11.2013)
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Journal Article
Systematic review and mixed treatment comparison of randomized evidence for empirical, pre-emptive and directed treatment strategies for invasive mould disease: Pathways for managing invasive fungal disease in immunocompromised patients
FREEMANTLE, Nick, THARMANATHAN, Puvan, HERBRECHT, Raoul
Published in Journal of antimicrobial chemotherapy (2011)
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Published in Journal of antimicrobial chemotherapy (2011)
Journal Article
Poor reporting quality of key Randomization and Allocation Concealment details is still prevalent among published RCTs in 2011: a review
Clark, Laura, Schmidt, Ulrike, Tharmanathan, Puvan, Adamson, Joy, Hewitt, Catherine, Torgerson, David
Published in Journal of evaluation in clinical practice (01.08.2013)
Published in Journal of evaluation in clinical practice (01.08.2013)
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Journal Article