Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy
Cabezas-Wallscheid, Nina, Buettner, Florian, Sommerkamp, Pia, Klimmeck, Daniel, Ladel, Luisa, Thalheimer, Frederic B., Pastor-Flores, Daniel, Roma, Leticia P., Renders, Simon, Zeisberger, Petra, Przybylla, Adriana, Schönberger, Katharina, Scognamiglio, Roberta, Altamura, Sandro, Florian, Carolina M., Fawaz, Malak, Vonficht, Dominik, Tesio, Melania, Collier, Paul, Pavlinic, Dinko, Geiger, Hartmut, Schroeder, Timm, Benes, Vladimir, Dick, Tobias P., Rieger, Michael A., Stegle, Oliver, Trumpp, Andreas
Published in Cell (18.05.2017)
Published in Cell (18.05.2017)
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Journal Article
In vivo generated human CAR T cells eradicate tumor cells
Agarwal, Shiwani, Weidner, Tatjana, Thalheimer, Frederic B, Buchholz, Christian J
Published in Oncoimmunology (02.12.2019)
Published in Oncoimmunology (02.12.2019)
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Journal Article
In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome
Pfeiffer, Anett, Thalheimer, Frederic B, Hartmann, Sylvia, Frank, Annika M, Bender, Ruben R, Danisch, Simon, Costa, Caroline, Wels, Winfried S, Modlich, Ute, Stripecke, Renata, Verhoeyen, Els, Buchholz, Christian J
Published in EMBO molecular medicine (01.11.2018)
Published in EMBO molecular medicine (01.11.2018)
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Journal Article
Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4
Jamali, Arezoo, Hadjati, Jamshid, Madjd, Zahra, Mirzaei, Hamid Reza, Thalheimer, Frederic B, Agarwal, Shiwani, Bonig, Halvard, Ullrich, Evelyn, Hartmann, Jessica
Published in Frontiers in immunology (28.08.2020)
Published in Frontiers in immunology (28.08.2020)
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Journal Article
CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes
Kapitza, Laura, Ho, Naphang, Kerzel, Thomas, Frank, Annika M, Thalheimer, Frederic B, Jamali, Arezoo, Schaser, Thomas, Buchholz, Christian J, Hartmann, Jessica
Published in Frontiers in immunology (14.08.2023)
Published in Frontiers in immunology (14.08.2023)
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Journal Article
Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed—Sternberg cells
Rengstl, Benjamin, Newrzela, Sebastian, Heinrich, Tim, Weiser, Christian, Thalheimer, Frederic B., Schmid, Frederike, Warner, Kathrin, Hartmann, Sylvia, Schroeder, Timm, Küppers, Ralf, Rieger, Michael A., Hansmann, Martin-Leo
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Journal Article
CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms
Charitidis, Filippos T, Adabi, Elham, Ho, Naphang, Braun, Angela H, Tierney, Ciara, Strasser, Lisa, Thalheimer, Frederic B, Childs, Liam, Bones, Jonathan, Clarke, Colin, Buchholz, Christian J
Published in Advanced science (01.12.2023)
Published in Advanced science (01.12.2023)
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Journal Article
Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal
Rabenhorst, Uta, Thalheimer, Frederic B., Gerlach, Katharina, Kijonka, Marek, Böhm, Stefanie, Krause, Daniela S., Vauti, Franz, Arnold, Hans-Henning, Schroeder, Timm, Schnütgen, Frank, von Melchner, Harald, Rieger, Michael A., Zörnig, Martin
Published in Cell reports (Cambridge) (30.06.2015)
Published in Cell reports (Cambridge) (30.06.2015)
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Journal Article
Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells
Thalheimer, Frederic B., Wingert, Susanne, De Giacomo, Pangrazio, Haetscher, Nadine, Rehage, Maike, Brill, Boris, Theis, Fabian J., Hennighausen, Lothar, Schroeder, Timm, Rieger, Michael A.
Published in Stem cell reports (08.07.2014)
Published in Stem cell reports (08.07.2014)
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Journal Article
The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia
Rafiei, Anahita, Mian, Afsar Ali, Döring, Claudia, Metodieva, Anna, Oancea, Claudia, Thalheimer, Frederic B, Hansmann, Martin Leo, Ottmann, Oliver Gerhard, Ruthardt, Martin
Published in PLoS genetics (01.04.2015)
Published in PLoS genetics (01.04.2015)
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Journal Article
In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes
Agarwal, Shiwani, Hanauer, Julia D.S., Frank, Annika M., Riechert, Vanessa, Thalheimer, Frederic B., Buchholz, Christian J.
Published in Molecular therapy (05.08.2020)
Published in Molecular therapy (05.08.2020)
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Journal Article
Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain
Lückerath, Katharina, Kirkin, Vladimir, Melzer, Inga Maria, Thalheimer, Frederic B., Siele, Dagmar, Milani, Wiebke, Adler, Thure, Aguilar-Pimentel, Antonio, Horsch, Marion, Michel, Geert, Beckers, Johannes, Busch, Dirk H., Ollert, Markus, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabĕ de Angelis, Martin, Staal, Frank J.T., Rajalingam, Krishnaraj, Hueber, Anne-Odile, Strobl, Lothar J., Zimber-Strobl, Ursula, Zörnig, Martin
Published in Blood (13.01.2011)
Published in Blood (13.01.2011)
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Journal Article
DNA‐damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival
Wingert, Susanne, Thalheimer, Frederic B., Haetscher, Nadine, Rehage, Maike, Schroeder, Timm, Rieger, Michael A.
Published in Stem cells (Dayton, Ohio) (01.03.2016)
Published in Stem cells (Dayton, Ohio) (01.03.2016)
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Journal Article
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery
Theuerkauf, Samuel A, Herrera-Carrillo, Elena, John, Fabian, Zinser, Luca J, Molina, Mariano A, Riechert, Vanessa, Thalheimer, Frederic B, Börner, Kathleen, Grimm, Dirk, Chlanda, Petr, Berkhout, Ben, Buchholz, Christian J
Published in Biomaterials (01.12.2023)
Published in Biomaterials (01.12.2023)
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Journal Article
T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8
Demircan, Muhammed Burak, Zinser, Luca J., Michels, Alexander, Guaza-Lasheras, Mar, John, Fabian, Gorol, Johanna M., Theuerkauf, Samuel A., Günther, Dorothee M., Grimm, Dirk, Greten, Florian R., Chlanda, Petr, Thalheimer, Frederic B., Buchholz, Christian J.
Published in Molecular therapy (02.10.2024)
Published in Molecular therapy (02.10.2024)
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Journal Article
STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling
Haetscher, Nadine, Feuermann, Yonatan, Wingert, Susanne, Rehage, Maike, Thalheimer, Frederic B, Weiser, Christian, Bohnenberger, Hanibal, Jung, Klaus, Schroeder, Timm, Serve, Hubert, Oellerich, Thomas, Hennighausen, Lothar, Rieger, Michael A
Published in Nature communications (25.11.2015)
Published in Nature communications (25.11.2015)
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Journal Article
Combining T-cell–specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors
Frank, Annika M., Braun, Angela H., Scheib, Lea, Agarwal, Shiwani, Schneider, Irene C., Fusil, Floriane, Perian, Séverine, Sahin, Ugur, Thalheimer, Frederic B., Verhoeyen, Els, Buchholz, Christian J.
Published in Blood advances (24.11.2020)
Published in Blood advances (24.11.2020)
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