Intracerebroventricular amyloid-β antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice
Thakker, Deepak R, Weatherspoon, Marcy R, Harrison, Jonathan, Keene, Thomas E, Lane, Deanna S, Kaemmerer, William F, Stewart, Gregory R, Shafer, Lisa L
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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Journal Article
Neurochemical and Behavioral Consequences of Widespread Gene Knockdown in the Adult Mouse Brain by Using Nonviral RNA Interference
Thakker, Deepak R., Natt, Francois, Hüsken, Dieter, Maier, Rainer, Müller, Matthias, van der Putten, Herman, Hoyer, Daniel, Cryan, John F., Bloom, Floyd E.
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2004)
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Journal Article
Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum
GRONDIN, Richard, KAYTOR, Michael D, KAEMMERER, William F, YI AI, NELSON, Peter T, THAKKER, Deepak R, HEISEL, Jennifer, WEATHERSPOON, Marcy R, BLUM, Janelle L, BURRIGHT, Eric N, ZHIMING ZHANG
Published in Brain (London, England : 1878) (01.04.2012)
Published in Brain (London, England : 1878) (01.04.2012)
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Journal Article
Widespread brain distribution and activity following i.c.v. infusion of anti‐β‐secretase (BACE1) in nonhuman primates
Yadav, Daniela Bumbaca, Maloney, Janice A, Wildsmith, Kristin R, Fuji, Reina N, Meilandt, William J, Solanoy, Hilda, Lu, Yanmei, Peng, Kun, Wilson, Blair, Chan, Pamela, Gadkar, Kapil, Kosky, Andrew, Goo, Marisa, Daugherty, Ann, Couch, Jessica A, Keene, Thomas, Hayes, Karen, Nikolas, Lisa Jungbauer, Lane, Deanna, Switzer, Robert, Adams, Eric, Watts, Ryan J, Scearce‐Levie, Kimberly, Prabhu, Saileta, Shafer, Lisa, Thakker, Deepak R, Hildebrand, Keith, Atwal, Jasvinder K
Published in British journal of pharmacology (01.11.2017)
Published in British journal of pharmacology (01.11.2017)
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Journal Article
Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice
Thakker, Deepak R, Sankaranarayanan, Sethu, Weatherspoon, Marcy R, Harrison, Jonathan, Pierdomenico, Maria, Heisel, Jennifer M, Thompson, Lorin A, Haskell, Roy, Grace, James E, Taylor, Sarah J, Albright, Charles F, Shafer, Lisa L
Published in The Journal of neuroscience (29.04.2015)
Published in The Journal of neuroscience (29.04.2015)
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Journal Article
Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse
O'Connor, Richard M., Thakker, Deepak R., Schmutz, Markus, van der Putten, Herman, Hoyer, Daniel, Flor, Peter J., Cryan, John F.
Published in Neuropharmacology (01.09.2013)
Published in Neuropharmacology (01.09.2013)
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Journal Article
Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk
Mandyam, Chitra D, Thakker, Deepak R, Christensen, Jennifer L, Standifer, Kelly M
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2002)
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Journal Article
Mu-opioid-induced desensitization of opioid receptor-like 1 and mu-opioid receptors: differential intracellular signaling determines receptor sensitivity
Mandyam, Chitra D, Thakker, Deepak R, Standifer, Kelly M
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
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Journal Article
Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders
Hoyer, Daniel, Thakker, Deepak R, Natt, François, Maier, Rainer, Huesken, Dieter, Müller, Matthias, Flor, Peter, VAN DER Putten, Herman, Schmutz, Markus, Bilbe, Graeme, Cryan, John F
Published in Journal of receptors and signal transduction (01.01.2006)
Published in Journal of receptors and signal transduction (01.01.2006)
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Journal Article
Orphanin FQ/nociceptin blocks chronic morphine-induced tyrosine hydroxylase upregulation
Thakker, Deepak R, Standifer, Kelly M
Published in Brain research. Molecular brain research. (30.09.2002)
Published in Brain research. Molecular brain research. (30.09.2002)
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Journal Article
Widespread brain distribution and activity following i.c.v. infusion of anti-[beta]-secretase (BACE1) in nonhuman primates
Yadav, Daniela Bumbaca, Maloney, Janice A, Wildsmith, Kristin R, Fuji, Reina N, Meilandt, William J, Solanoy, Hilda, Lu, Yanmei, Peng, Kun, Wilson, Blair, Chan, Pamela, Gadkar, Kapil, Kosky, Andrew, Goo, Marisa, Daugherty, Ann, Couch, Jessica A, Keene, Thomas, Hayes, Karen, Nikolas, Lisa Jungbauer, Lane, Deanna, Switzer, Robert, Adams, Eric, Watts, Ryan J, Scearce-Levie, Kimberly, Prabhu, Saileta, Shafer, Lisa, Thakker, Deepak R, Hildebrand, Keith, Atwal, Jasvinder K
Published in British journal of pharmacology (01.11.2017)
Published in British journal of pharmacology (01.11.2017)
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Journal Article
Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice
Thakker, Deepak R, Sankaranarayanan, Sethu, Weatherspoon, Marcy R, Harrison, Jonathan, Pierdomenico, Maria, Heisel, Jennifer M, Thompson, Lorin A, Haskell, Roy, Grace, James E, Taylor, Sarah J, Albright, Charles F, Shafer, Lisa L
Published in The Journal of neuroscience (29.04.2015)
Published in The Journal of neuroscience (29.04.2015)
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Journal Article
Intracerebroventricular amyloid-[beta] antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice
Thakker, Deepak R, Weatherspoon, Marcy R, Harrison, Jonathan, Keene, Thomas E, Lane, Deanna S, Kaemmerer, William F, Stewart, Gregory R, Shafer, Lisa L
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Journal Article
Intracerebroventricular amyloid-β antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice
Thakker, Deepak R, Weatherspoon, Marcy R, Harrison, Jonathan, Keene, Thomas E, Lane, Deanna S, Kaemmerer, William F, Stewart, Gregory R, Shafer, Lisa L
Published in Proceedings of the National Academy of Sciences - PNAS (2009)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (2009)
Journal Article
μ-Opioid-Induced Desensitization of Opioid Receptor-Like 1 and μ-Opioid Receptors: Differential Intracellular Signaling Determines Receptor Sensitivity
Chitra D. Mandyam, Deepak R. Thakker, Kelly M. Standifer
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
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Journal Article