Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia
Arcangeli, Silvia, Rotiroti, Maria Caterina, Bardelli, Marco, Simonelli, Luca, Magnani, Chiara Francesca, Biondi, Andrea, Biagi, Ettore, Tettamanti, Sarah, Varani, Luca
Published in Molecular therapy (02.08.2017)
Published in Molecular therapy (02.08.2017)
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Fully equipped CARs to address tumor heterogeneity, enhance safety, and improve the functionality of cellular immunotherapies
Alviano, Antonio Maria, Biondi, Marta, Grassenis, Erica, Biondi, Andrea, Serafini, Marta, Tettamanti, Sarah
Published in Frontiers in immunology (03.06.2024)
Published in Frontiers in immunology (03.06.2024)
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Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche
Alberti, Gaia, Arsuffi, Corinne, Pievani, Alice, Salerno, Domenico, Mantegazza, Francesco, Dazzi, Francesco, Biondi, Andrea, Tettamanti, Sarah, Serafini, Marta
Published in Frontiers in immunology (25.05.2023)
Published in Frontiers in immunology (25.05.2023)
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CARs are sharpening their weapons
Pievani, Alice, Biondi, Marta, Tettamanti, Sarah, Biondi, Andrea, Dotti, Gianpietro, Serafini, Marta
Published in Journal for immunotherapy of cancer (31.01.2024)
Published in Journal for immunotherapy of cancer (31.01.2024)
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Transposon-Based CAR T Cells in Acute Leukemias: Where are We Going?
Magnani, Chiara F, Tettamanti, Sarah, Alberti, Gaia, Pisani, Ilaria, Biondi, Andrea, Serafini, Marta, Gaipa, Giuseppe
Published in Cells (Basel, Switzerland) (27.05.2020)
Published in Cells (Basel, Switzerland) (27.05.2020)
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Functional Activity of Cytokine-Induced Killer Cells Enhanced by CAR-CD19 Modification or by Soluble Bispecific Antibody Blinatumomab
Zaninelli, Silvia, Panna, Silvia, Tettamanti, Sarah, Melita, Giusi, Doni, Andrea, D'Autilia, Francesca, Valgardsdottir, Rut, Gotti, Elisa, Rambaldi, Alessandro, Golay, Josée, Introna, Martino
Published in Antibodies (Basel) (30.08.2024)
Published in Antibodies (Basel) (30.08.2024)
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Catch me if you can: how AML and its niche escape immunotherapy
Tettamanti, Sarah, Pievani, Alice, Biondi, Andrea, Dotti, Gianpietro, Serafini, Marta
Published in Leukemia (01.01.2022)
Published in Leukemia (01.01.2022)
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New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future
Biagi, Ettore, Marin, Virna, Attianese, Greta Maria Paola Giordano, Pizzitola, Irene, Tettamanti, Sarah, Cribioli, Elisabetta, Biondi, Andrea
Published in Italian journal of pediatrics (22.09.2011)
Published in Italian journal of pediatrics (22.09.2011)
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Journal Article
Bone Marrow Stroma Impairs CAR-T Cell Proliferation and Function: Mechanistic Insights
Dazzi, Francesco, Savoldelli, Roberto, Pievani, Alice, Tettamanti, Sarah, Giacomini, Chiara, Kozlowska, Anna, Serafini, Marta
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Sleeping Beauty-engineered CAR T cells achieve antileukemic activity without severe toxicities
Magnani, Chiara F, Gaipa, Giuseppe, Lussana, Federico, Belotti, Daniela, Gritti, Giuseppe, Napolitano, Sara, Matera, Giada, Cabiati, Benedetta, Buracchi, Chiara, Borleri, Gianmaria, Fazio, Grazia, Zaninelli, Silvia, Tettamanti, Sarah, Cesana, Stefania, Colombo, Valentina, Quaroni, Michele, Cazzaniga, Giovanni, Rovelli, Attilio, Biagi, Ettore, Galimberti, Stefania, Calabria, Andrea, Benedicenti, Fabrizio, Montini, Eugenio, Ferrari, Silvia, Introna, Martino, Balduzzi, Adriana, Valsecchi, Maria Grazia, Dastoli, Giuseppe, Rambaldi, Alessandro, Biondi, Andrea
Published in The Journal of clinical investigation (01.11.2020)
Published in The Journal of clinical investigation (01.11.2020)
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Combining the Expression of CD33.CAR and CXCR4 to Increase CAR-CIK Cell Homing to Bone Marrow Niche and Leukemic Stem Cell Eradication in Acute Myeloid Leukemia
Biondi, Marta, Cerina, Beatrice, Tomasoni, Chiara, Dotti, Gianpietro, Tettamanti, Sarah, Biondi, Andrea, Pievani, Alice, Serafini, Marta
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Overexpression of CXCR4 Enhances the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Biondi, Marta, Galimberti, Stefania, Cerina, Beatrice, Tomasoni, Chiara, Dotti, Gianpietro, Tettamanti, Sarah, Biondi, Andrea, Pievani, Alice, Serafini, Marta
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the acute myeloid leukemia burden
Biondi, Marta, Tettamanti, Sarah, Galimberti, Stefania, Cerina, Beatrice, Tomasoni, Chiara, Piazza, Rocco, Donsante, Samantha, Bido, Simone, Perriello, Vincenzo Maria, Broccoli, Vania, Doni, Andrea, Dazzi, Francesco, Mantovani, Alberto, Dotti, Gianpietro, Biondi, Andrea, Pievani, Alice, Serafini, Marta
Published in Blood (25.05.2023)
Published in Blood (25.05.2023)
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Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor
Tettamanti, Sarah, Marin, Virna, Pizzitola, Irene, Magnani, Chiara F., Giordano Attianese, Greta M. P., Cribioli, Elisabetta, Maltese, Francesca, Galimberti, Stefania, Lopez, Angel F., Biondi, Andrea, Bonnet, Dominique, Biagi, Ettore
Published in British journal of haematology (01.05.2013)
Published in British journal of haematology (01.05.2013)
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Manufacturing, Characterization and Anti-Tumor Activity of Allogeneic CD19-CAR Cytokine-Induced Killer (CIK) Cells Engineered with Non-Viral Sleeping Beauty Transposon System and Armored with IL-18
Contreras-Ruiz, Laura, Pace, Barcley, Kohnke, Dora E, Viruet, Lindsey, Adams, Melissa, Krisko, John F, Leesnitzer, Noah, Velie, Marissa, Tettamanti, Sarah, Pisani, Ilaria, Melita, Giusi, Biondi, Andrea, Rambaldi, Alessandro, Tcherepanova, Irina Y, Brentjens, Renier, Nicolette, Charles A
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
CD123 and CD33 Co-Targeting By Balanced Signaling on CAR-CIK Cells Reduces Potential Off-Target Toxicity While Preserving the Anti-Leukemic Activity of Acute Myeloid Leukemia
Perriello, Vincenzo Maria, Rotiroti, Maria Caterina, Pisani, Ilaria, Alberti, Gaia, Pianigiani, Giulia, Rossi, Roberta, Ciaurro, Valerio, Serafini, Marta, Martelli, Maria Paola, Falini, Brunangelo, Biondi, Andrea, Tettamanti, Sarah
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia
Magnani, Chiara F, Mezzanotte, Claudia, Cappuzzello, Claudia, Bardini, Michela, Tettamanti, Sarah, Fazio, Grazia, Cooper, Laurence J N, Dastoli, Giuseppe, Cazzaniga, Giovanni, Biondi, Andrea, Biagi, Ettore
Published in Human gene therapy (01.05.2018)
Published in Human gene therapy (01.05.2018)
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Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use
Gotti, Elisa, Tettamanti, Sarah, Zaninelli, Silvia, Cuofano, Carolina, Cattaneo, Irene, Rotiroti, Maria Caterina, Cribioli, Sabrina, Alzani, Rachele, Rambaldi, Alessandro, Introna, Martino, Golay, Josée
Published in Cytotherapy (Oxford, England) (01.03.2022)
Published in Cytotherapy (Oxford, England) (01.03.2022)
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Journal Article
Acute Myeloid Leukemia Targeting by Chimeric Antigen Receptor T Cells: Bridging the Gap from Preclinical Modeling to Human Studies
Rotiroti, Maria Caterina, Arcangeli, Silvia, Casucci, Monica, Perriello, Vincenzo, Bondanza, Attilio, Biondi, Andrea, Tettamanti, Sarah, Biagi, Ettore
Published in Human gene therapy (01.03.2017)
Published in Human gene therapy (01.03.2017)
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