First-in-human, phase I dose-escalation study of the safety, pharmacokinetics, and pharmacodynamics of RO5126766, a first-in-class dual MEK/RAF inhibitor in patients with solid tumors
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Published in Clinical cancer research (01.09.2012)
Published in Clinical cancer research (01.09.2012)
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CD8 Presence and Dynamics in Glofitamab-Treated Patients with Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Using the CD8-Specific PET Tracer 89Zr-Crefmirlimab Berdoxam
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Phase I Expansion and Pharmacodynamic Study of the Oral MEK Inhibitor RO4987655 (CH4987655) in Selected Patients with Advanced Cancer with RAS-RAF Mutations
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Published in Clinical cancer research (15.08.2014)
Published in Clinical cancer research (15.08.2014)
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The PET-tracer 89Zr-Df-IAB22M2C enables monitoring of intratumoral CD8 T cell infiltrates in tumor-bearing humanized mice after T cell bispecific antibody treatment
Griessinger, Christoph M, Olafsen, Tove, Mascioni, Alessandro, Jiang, Ziyue Karen, Zamilpa, Charles, Jia, Fang, Torgov, Michael, Romero, Jason M, Marchioni, Filippo, Satpayev, Daulet, Lee, Chenyu, Zhang, Green, Nayak, Tapan K, Pincha, Mudita, Amann, Maria, Mohan, Preethi Latha Bhavani, Richard, Marine, Nicolini, Valeria G, Sam, Johannes, Claus, Christina, Ferrara, Claudia, Brünker, Peter, Bacac, Marina, Umana, Pablo, Rüttinger, Dominik, Wilson, Ian A, Gudas, Jean, Klein, Christian, Tessier, Jean J L
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Published in Cancer research (Chicago, Ill.) (01.07.2020)
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Phase I Dose-Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of the MEK Inhibitor RO4987655 (CH4987655) in Patients with Advanced Solid Tumors
LEIJEN, Suzanne, MIDDLETON, Mark R, TESSIER, Jean J. L, SHOCHAT, Eliezer, BLOTNER, Steve, MERESSE NAEGELEN, Valerie, SCHELLENS, Jan H. M, EBERHARDT, Wilfried Ernst Erich, TRESCA, Patricia, KRAEBER-BODERE, Françoise, DIERAS, Veronique, SCHEULEN, Max E, GUPTA, Avinash, LOPEZ-VALVERDE, Vanesa, XU, Zhi-Xin, RUEGER, Ruediger
Published in Clinical cancer research (01.09.2012)
Published in Clinical cancer research (01.09.2012)
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Dynamic contrast-enhanced MRI of vascular changes induced by the VEGF-signalling inhibitor ZD4190 in human tumour xenografts
Checkley, David, Tessier, Jean J.L., Wedge, Stephen R., Dukes, Michael, Kendrew, Jane, Curry, Brenda, Middleton, Brian, Waterton, John C.
Published in Magnetic resonance imaging (01.06.2003)
Published in Magnetic resonance imaging (01.06.2003)
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