Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
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Published in Development (Cambridge) (15.03.2017)
Published in Development (Cambridge) (15.03.2017)
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Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
van Meer, Berend J., Krotenberg, Ana, Sala, Luca, Davis, Richard P., Eschenhagen, Thomas, Denning, Chris, Tertoolen, Leon G. J., Mummery, Christine L.
Published in Nature communications (20.09.2019)
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Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
Sala, Luca, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Mummery, Christine L, Bellin, Milena
Published in Journal of visualized experiments (12.05.2017)
Published in Journal of visualized experiments (12.05.2017)
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Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure
Kosmidis, Georgios, Bellin, Milena, Ribeiro, Marcelo C., van Meer, Berend, Ward-van Oostwaard, Dorien, Passier, Robert, Tertoolen, Leon G.J., Mummery, Christine L., Casini, Simona
Published in Biochemical and biophysical research communications (27.11.2015)
Published in Biochemical and biophysical research communications (27.11.2015)
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MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo
Sala, Luca, van Meer, Berend J, Tertoolen, Leon G.J, Bakkers, Jeroen, Bellin, Milena, Davis, Richard P, Denning, Chris, Dieben, Michel A.E, Eschenhagen, Thomas, Giacomelli, Elisa, Grandela, Catarina, Hansen, Arne, Holman, Eduard R, Jongbloed, Monique R.M, Kamel, Sarah M, Koopman, Charlotte D, Lachaud, Quentin, Mannhardt, Ingra, Mol, Mervyn P.H, Mosqueira, Diogo, Orlova, Valeria V, Passier, Robert, Ribeiro, Marcelo C, Saleem, Umber, Smith, Godfrey L, Burton, Francis L, Mummery, Christine L
Published in Circulation research (02.02.2018)
Published in Circulation research (02.02.2018)
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Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Qiao, Xiaohang, van der Zanden, Sabina Y., Wander, Dennis P. A., Borràs, Daniel M., Song, Ji-Ying, Li, Xiaoyang, van Duikeren, Suzanne, van Gils, Noortje, Rutten, Arjo, van Herwaarden, Tessa, van Tellingen, Olaf, Giacomelli, Elisa, Bellin, Milena, Orlova, Valeria, Tertoolen, Leon G. J., Gerhardt, Sophie, Akkermans, Jimmy J., Bakker, Jeroen M., Zuur, Charlotte L., Pang, Baoxu, Smits, Anke M., Mummery, Christine L., Smith, Linda, Arens, Ramon, Li, Junmin, Overkleeft, Hermen S., Neefjes, Jacques
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2020)
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Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome
Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L
Published in The EMBO journal (11.12.2013)
Published in The EMBO journal (11.12.2013)
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A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness
Ribeiro, Marcelo C., Slaats, Rolf H., Schwach, Verena, Rivera-Arbelaez, José M., Tertoolen, Leon G.J., van Meer, Berend J., Molenaar, Robert, Mummery, Christine L., Claessens, Mireille M.A.E., Passier, Robert
Published in Journal of molecular and cellular cardiology (01.04.2020)
Published in Journal of molecular and cellular cardiology (01.04.2020)
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Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes
Dambrot, Cheryl, Braam, Stefan R., Tertoolen, Leon G. J., Birket, Matthew, Atsma, Douwe E., Mummery, Christine L.
Published in Journal of cellular and molecular medicine (01.08.2014)
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Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias
Brandão, Karina O., van den Brink, Lettine, Miller, Duncan C., Grandela, Catarina, van Meer, Berend J., Mol, Mervyn P.H., de Korte, Tessa, Tertoolen, Leon G.J., Mummery, Christine L., Sala, Luca, Verkerk, Arie O., Davis, Richard P.
Published in Stem cell reports (10.11.2020)
Published in Stem cell reports (10.11.2020)
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Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts
van Meer, Berend J, Sala, Luca, Tertoolen, Leon G J, Smith, Godfrey L, Burton, Francis L, Mummery, Christine L
Published in Current protocols in human genetics (01.10.2018)
Published in Current protocols in human genetics (01.10.2018)
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Dimerization of receptor protein-tyrosine phosphatase alpha in living cells
Tertoolen, L G, Blanchetot, C, Jiang, G, Overvoorde, J, Gadella, Jr, T W, Hunter, T, den Hertog, J
Published in BMC cell biology (01.06.2001)
Published in BMC cell biology (01.06.2001)
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Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
Giacomelli, Elisa, Meraviglia, Viviana, Campostrini, Giulia, Cochrane, Amy, Cao, Xu, van Helden, Ruben W.J., Krotenberg Garcia, Ana, Mircea, Maria, Kostidis, Sarantos, Davis, Richard P., van Meer, Berend J., Jost, Carolina R., Koster, Abraham J., Mei, Hailiang, Míguez, David G., Mulder, Aat A., Ledesma-Terrón, Mario, Pompilio, Giulio, Sala, Luca, Salvatori, Daniela C.F., Slieker, Roderick C., Sommariva, Elena, de Vries, Antoine A.F., Giera, Martin, Semrau, Stefan, Tertoolen, Leon G.J., Orlova, Valeria V., Bellin, Milena, Mummery, Christine L.
Published in Cell stem cell (04.06.2020)
Published in Cell stem cell (04.06.2020)
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FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
van der Horst, Armando, Tertoolen, Leon G J, de Vries-Smits, Lydia M M, Frye, Roy A, Medema, René H, Burgering, Boudewijn M T
Published in The Journal of biological chemistry (09.07.2004)
Published in The Journal of biological chemistry (09.07.2004)
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Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)
Sala, Luca, Ward-van Oostwaard, Dorien, Tertoolen, Leon G. J., Mummery, Christine L, Bellin, Milena
Published in Journal of visualized experiments (12.05.2017)
Published in Journal of visualized experiments (12.05.2017)
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Regulation of receptor protein-tyrosine phosphatase α by oxidative stress
Blanchetot, Christophe, G.J.Tertoolen, Leon, den Hertog, Jeroen
Published in The EMBO journal (15.02.2002)
Published in The EMBO journal (15.02.2002)
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Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome: Isogenic pairs of LQT2 pluripotent stem cells
Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L
Published in The EMBO journal (11.12.2013)
Published in The EMBO journal (11.12.2013)
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