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Chrencik, Jill E., Patny, Akshay, Leung, Iris K., Korniski, Brian, Emmons, Thomas L., Hall, Troii, Weinberg, Robin A., Gormley, Jennifer A., Williams, Jennifer M., Day, Jacqueline E., Hirsch, Jeffrey L., Kiefer, James R., Leone, Joseph W., Fischer, H. David, Sommers, Cynthia D., Huang, Horng-Chih, Jacobsen, E.J., Tenbrink, Ruth E., Tomasselli, Alfredo G., Benson, Timothy E.
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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds
Meyers, Marvin J., Long, Scott A., Pelc, Matthew J., Wang, Jane L., Bowen, Scott J., Walker, Mark C., Schweitzer, Barbara A., Madsen, Heather M., Tenbrink, Ruth E., McDonald, Joseph, Smith, Sarah E., Foltin, Susan, Beidler, David, Thorarensen, Atli
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Thienopyrimidine-based P2Y12 platelet aggregation inhibitors
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Published in Bioorganic & medicinal chemistry letters (15.10.2009)
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1
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Published in Bioorganic & medicinal chemistry letters (15.06.2007)
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
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Structure based design of novel irreversible FAAH inhibitors
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Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist
TenBrink, Ruth E, Bergh, Carol L, Duncan, J. Neil, Harris, Douglas W, Huff, R. M, Lahti, Robert A, Lawson, Charles F, Lutzke, Barry S, Martin, Iain J, Rees, Susan A, Schlachter, Siusaidh K, Sih, John C, Smith, Martin W
Published in Journal of medicinal chemistry (21.06.1996)
Published in Journal of medicinal chemistry (21.06.1996)
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Antagonist, Partial Agonist, and Full Agonist Imidazo[1,5-a]quinoxaline Amides and Carbamates Acting through the GABAA/Benzodiazepine Receptor
TenBrink, Ruth E, Im, Wha B, Sethy, Vimala H, Tang, Andrew H, Carter, Don B
Published in Journal of medicinal chemistry (01.03.1994)
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High-Affinity Partial Agonist Imidazo[1,5-a]quinoxaline Amides, Carbamates, and Ureas at the γ-Aminobutyric Acid A/Benzodiazepine Receptor Complex
Jacobsen, E. Jon, TenBrink, Ruth E, Stelzer, Lindsay S, Belonga, Kenneth L, Carter, Donald B, Im, Haesook K, Im, Wha Bin, Sethy, Vimala H, Tang, Andy H, VonVoigtlander, Philip F, Petke, James D
Published in Journal of medicinal chemistry (05.01.1996)
Published in Journal of medicinal chemistry (05.01.1996)
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Piperazine Imidazo[1,5-a]quinoxaline Ureas as High-Affinity GABAA Ligands of Dual Functionality
Jacobsen, E. Jon, Stelzer, Lindsay S, TenBrink, Ruth E, Belonga, Kenneth L, Carter, Donald B, Im, Haesook K, Im, Wha Bin, Sethy, Vimala H, Tang, Andy H, VonVoigtlander, Philip F, Petke, James D, Zhong, Wei-Zhu, Mickelson, John W
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere
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Published in Journal of medicinal chemistry (16.04.1993)
Published in Journal of medicinal chemistry (16.04.1993)
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Potent and selective isophthalamide S 2 hydroxyethylamine inhibitors of BACE1
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Published in Bioorganic & medicinal chemistry letters (15.06.2007)
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
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Thienopyrimidine-based P2Y sub(12) platelet aggregation inhibitors
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Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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Thienopyrimidine-based P2Y 12 platelet aggregation inhibitors
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Published in Bioorganic & medicinal chemistry letters (2009)
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PYRROLO [2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF JANUS-RELATED KINASES (JAK)
UNWALLA RAYOMAND JAL, GONZALES ANDREA, JOHNSON TIMOTHY ALLAN, STROHBACH JOSEPH WALTER, TRZUPEK JOHN DAVID, TENBRINK RUTH E, MITTON FRY MARK J, FLANAGAN MARK EDWARD, KAILA NEELU, BROWN MATTHEW FRANK, FENWICK ASHLEY EDWARD, VAZQUEZ MICHAEL L, PARIKH MIHIR D
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Year of Publication 01.10.2015
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Potent and selective isophthalamide S sub(2) hydroxyethylamine inhibitors of BACE1
Kortum, Steven W, Benson, Timothy E, Bienkowski, Michael J, Emmons, Thomas L, Prince, DBryan, Paddock, Donna J, Tomasselli, Alfredo G, Moon, Joseph B, LaBorde, Alice, TenBrink, Ruth E
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABA(A) ligands of dual functionality
Jacobsen, EJ, Stelzer, LS, TenBrink, RE, Belonga, KL, Carter, DB, Im, HK, Im, WB, Sethy, VH, Tang, AH, VonVoigtlander, PF, Petke, JD, Zhong, WZ, Mickelson, JW
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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