Venetoclax induces rapid elimination of NPM1 mutant measurable residual disease in combination with low‐intensity chemotherapy in acute myeloid leukaemia
Tiong, Ing S., Dillon, Richard, Ivey, Adam, Teh, Tse‐Chieh, Nguyen, Phillip, Cummings, Nicholas, Taussig, David C., Latif, Annie‐Louise, Potter, Nicola E., Runglall, Manohursingh, Russell, Nigel H., Raj, Kavita, Schwarer, Anthony P., Fong, Chun Yew, Grigg, Andrew P., Wei, Andrew H.
Published in British journal of haematology (01.03.2021)
Published in British journal of haematology (01.03.2021)
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Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia
Moujalled, Donia M., Pomilio, Giovanna, Ghiurau, Corina, Ivey, Adam, Salmon, Jessica, Rijal, Sewa, Macraild, Sarah, Zhang, Lan, Teh, Tse-Chieh, Tiong, Ing-Soo, Lan, Ping, Chanrion, Maia, Claperon, Audrey, Rocchetti, Francesca, Zichi, Adrien, Kraus-Berthier, Laurence, Wang, Youzhen, Halilovic, Ensar, Morris, Erick, Colland, Frédéric, Segal, David, Huang, David, Roberts, Andrew W., Maragno, Ana Leticia, Lessene, Guillaume, Geneste, Olivier, Wei, Andrew H.
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription
Thomas, Daniel, Powell, Jason A., Vergez, Francois, Segal, David H., Nguyen, Nhu-Y.N., Baker, Adele, Teh, Tse-Chieh, Barry, Emma F., Sarry, Jean-Emmanuel, Lee, Erwin M., Nero, Tracy L., Jabbour, Anissa M., Pomilio, Giovanna, Green, Benjamin D., Manenti, Stéphane, Glaser, Stefan P., Parker, Michael W., Lopez, Angel F., Ekert, Paul G., Lock, Richard B., Huang, David C.S., Nilsson, Susie K., Récher, Christian, Wei, Andrew H., Guthridge, Mark A.
Published in Blood (01.08.2013)
Published in Blood (01.08.2013)
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Low-intensity venetoclax-based salvage as a bridge to allogeneic stem cell transplant in patients with acute myeloid leukemia failing conventional intensive chemotherapy
Ashby, Michael, Fleming, Shaun, Teh, Tse-Chieh, Tiong, Ing Soo, Inam, Shafqat, Curtis, David J., Patil, Sushrut, Vassili, Catherine, Chua, Chong Chyn
Published in Leukemia research (01.01.2024)
Published in Leukemia research (01.01.2024)
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Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts
Appelbaum, Jacob S., Wei, Andrew H., Mandrekar, Sumithra J., Tiong, Ing S., Chua, Chong Chyn, Teh, Tse-Chieh, Fong, Chun Yew, Ting, Stephen B., Weber, Daniela, Benner, Axel, Hill, Hannah, Saadati, Maral, Yin, Jun, Stone, Richard M., Garcia-Manero, Guillermo, Erba, Harry P., Uy, Geoffrey L., Marcucci, Guido, Larson, Richard A., Thomas, Abin, Freeman, Sylvie D., Almuina, Nuria Marquez, Döhner, Konstanze, Thomas, Ian, Russel, Nigel H., Döhner, Hartmut, Othus, Megan, Estey, Elihu H., Walter, Roland B.
Published in Leukemia (01.02.2024)
Published in Leukemia (01.02.2024)
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Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML
Rijal, Sewa, Fleming, Shaun, Cummings, Nik, Rynkiewicz, Natalie K., Ooms, Lisa M., Nguyen, Nhu-Y. N., Teh, Tse-Chieh, Avery, Sharon, McManus, Julie F., Papenfuss, Anthony T., McLean, Catriona, Guthridge, Mark A., Mitchell, Christina A., Wei, Andrew H.
Published in Blood (30.04.2015)
Published in Blood (30.04.2015)
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Hyperleukocytosis associated with delayed presentation among patients with acute leukemia during the COVID-19 pandemic
Tedjaseputra, Aditya, Kuzich, James A., Thiagarajah, Nisha, Teh, Tse-Chieh, McClelland, Julia, Rahman, Marzia, Brook, Rowena, Chua, Chong Chyn, Ong, Doen Ming, Tan, Shuh-Ying, Filshie, Robin, Fong, Chun Yew, Fedele, Pasquale, Bajel, Ashish, Shortt, Jake, Wei, Andrew H.
Published in Leukemia & lymphoma (19.09.2022)
Published in Leukemia & lymphoma (19.09.2022)
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Bortezomib-based antibody depletion for refractory autoimmune hematological diseases
Ratnasingam, Sumita, Walker, Patricia A., Tran, Huy, Kaplan, Zane S., McFadyen, James D., Tran, Huyen, Teh, Tse-Chieh, Fleming, Shaun, Catalano, John V., Chunilal, Sanjeev D., Johnston, Anna, Opat, Stephen S., Shortt, Jake
Published in Blood advances (29.11.2016)
Published in Blood advances (29.11.2016)
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A Prospective Phase 2 Study of Venetoclax and Low Dose Ara-C (VALDAC) to Target Rising Molecular Measurable Residual Disease and Early Relapse in Acute Myeloid Leukemia
Tiong, Ing S, Hiwase, Devendra, Abro, Emad Uddin, Bajel, Ashish, Palfreyman, Emma, Loo, Sun, Fleming, Shaun, Fong, Chun Yew, Teh, Tse-Chieh, Ivey, Adam, Wei, Andrew H
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Targeting Molecular Measurable Residual Disease and Low-Blast Relapse in AML With Venetoclax and Low-Dose Cytarabine: A Prospective Phase II Study (VALDAC)
Tiong, Ing Soo, Hiwase, Devendra K, Abro, Emad, Bajel, Ashish, Palfreyman, Emma, Beligaswatte, Ashanka, Reynolds, John, Anstee, Natasha, Nguyen, Tamia, Loo, Sun, Chua, Chong Chyn, Ashby, Michael, Wiltshire, Kaitlyn M, Fleming, Shaun, Fong, Chun Y, Teh, Tse-Chieh, Blombery, Piers, Dillon, Richard, Ivey, Adam, Wei, Andrew H
Published in Journal of clinical oncology (20.06.2024)
Published in Journal of clinical oncology (20.06.2024)
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Journal Article
A Prospective Phase 2 Study of Venetoclax and Low Dose Ara-C (VALDAC) to Target Rising Molecular Measurable Residual Disease and Early Relapse in Acute Myeloid Leukemia
Tiong, Ing S, Loo, Sun, Abro, Emad Uddin, Hiwase, Devendra, Fleming, Shaun, Bajel, Ashish, Palfreyman, Emma, Fong, Chun Yew, Teh, Tse-Chieh, Ivey, Adam, Wei, Andrew H.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Elenestinib, an Investigational, Next Generation KIT D816V Inhibitor, Reduces Mast Cell Burden, Improves Symptoms, and Has a Favorable Safety Profile in Patients with Indolent Systemic Mastocytosis: Analysis of the Harbor Trial
Tashi, Tsewang, Hermine, Olivier, Castells, Mariana, Guilarte, Mar, Sabato, Vito, Maurer, Marcus, Panse, Jens, Alvarez-Twose, Ivan, Cabral, Renata, Bird, Robert, Barete, Stéphane, Bouillet, Laurence, Hermans, Maud, Van Daele, Paul, González-De-Olano, David, Griffiths, Elizabeth A., Jurcic, Joseph, Dybedal, Ingunn, Damaj, Gandhi Laurent, Schafhausen, Philippe, Elena, Chiara, Teh, Tse-Chieh, Vachhani, Pankit, Labe, Caroline, Venugopal, Saranya, He, Kevin, Muñoz-González, Javier, Lampson, Ben, Scherber, Robyn, Bose, Prithviraj, Grattan, Clive, Pongdee, Thanai, George, Tracy I., Livideanu, Cristina Bulai
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Preliminary Safety and Efficacy of Bgb-11417, a Novel Bcl-2 Inhibitor, in Combination with Azacitidine in Patients with Acute Myeloid Leukemia (AML)
Shortt, Jake, Montesinos, Pau, Tan, Shuh Ying, Fong Ng, Teng, Fong, Chun Yew, Cannell, Paul, Rajagopal, Rajeev, Leitch, Sophia, Tan, Peter T., Ramanathan, Sundra, Gasiorowski, Robin, Lenton, Douglas Stuart, Teh, Tse-Chieh, Pérez-Simón, José Antonio, Grove, Carolyn, Huang, Xiaojun, DiNardo, Courtney D., Naidu, Katherine, Pariseau, Joseph, Cheng, Si, Liu, Yu, Co, Melannie, Chan, Wai Y., Guo, Haiyi, Wei, Andrew H.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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A Phase 2, Open-Label, Ascending Dose Study of Ker-050 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
Ross, David M, Arbelaez, Alejandro, Chee, Lynette C.Y., Fong, Chun Yew, Hiwase, Devendra, Kannourakis, George, Kwan, John, Liang, James, Puliyayil, Anish, Rose, Hannah, Tan, Shuhying, Teh, Tse-Chieh, Westerman, David Alan, Wight, Joel, Rovaldi, Chris, Furutani, Elissa M., Gaggi, Adrienne, Jiang, Ying, Lachey, Jenn, Natarajan, Harveen Dhillon, Ordonez, Claudia
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Combined BCL-2 and HDAC Targeting Has Potent and TP53 Independent Activity in AML
Salmon, Jessica M, Pomilio, Giovanna, Moujalled, Donia M, Macraild, Sarah, Teh, Charis E, Riajl, Sewa, Ivey, Adam, Teh, Tse-Chieh, Ekert, Paul G, Kraus-Berthier, Laurence, Kloos, Ioana, Schoumacher, Marie, Gray, Daniel, Wei, Andrew H
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Rapid Elimination of NPM1 Mutant Measurable Residual Disease (MRD) Using Low Intensity Venetoclax-Based Combinations in Acute Myeloid Leukemia (AML)
Tiong, Ing S, Dillon, Richard, Ivey, Adam, Teh, Tse-Chieh, Vassili, Catherine, Donati, Vanessa Roma, Taussig, David, Potter, Nicola, Jovanovic, Jelena, Kanda, Anju, Runglall, Manohursingh, Foot, Nicola, Valganon, Mikel, Russell, Nigel H., Raj, Kavita, Schwarer, Anthony P, Fong, Chun Yew, Grigg, Andrew, Knapper, Steven, Wei, Andrew H.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Bortezomib Yields High Response Rates in Antibody-Mediated Autoimmune Hematological Diseases Refractory to Conventional Immunosuppression
Ratnasingam, Sumita, Walker, Patricia A., Tran, Huy, Kaplan, Zane, McFadyen, James David, Tran, Huyen, Teh, Tse-Chieh, Wood, Erica M., Catalano, John V., Opat, Stephen, Shortt, Jake
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Eradication of Acute Myeloid Leukemia Is Enhanced By Combined Bcl-2 and Mcl-1 Targeting
Teh, Tse-Chieh, Nguyen, Nhu-Y, Glaser, Stefan, Moujalled, Donia, Pomilio, Giovanna, Huang, David CS, Guthridge, Mark, Wei, Andrew H
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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