Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
Tam, Constantine S., Trotman, Judith, Opat, Stephen, Burger, Jan A., Cull, Gavin, Gottlieb, David, Harrup, Rosemary, Johnston, Patrick B., Marlton, Paula, Munoz, Javier, Seymour, John F., Simpson, David, Tedeschi, Alessandra, Elstrom, Rebecca, Yu, Yiling, Tang, Zhiyu, Han, Lynn, Huang, Jane, Novotny, William, Wang, Lai, Roberts, Andrew W.
Published in Blood (12.09.2019)
Published in Blood (12.09.2019)
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Journal Article
A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study
Tam, Constantine S., Opat, Stephen, D'Sa, Shirley, Jurczak, Wojciech, Lee, Hui-Peng, Cull, Gavin, Owen, Roger G., Marlton, Paula, Wahlin, Björn E., Sanz, Ramón Garcia, McCarthy, Helen, Mulligan, Stephen, Tedeschi, Alessandra, Castillo, Jorge J., Czyz, Jaroslaw, Fernández de Larrea, Carlos, Belada, David, Libby, Edward, Matous, Jeffrey V., Motta, Marina, Siddiqi, Tanya, Tani, Monica, Trneny, Marek, Minnema, Monique C., Buske, Christian, Leblond, Veronique, Trotman, Judith, Chan, Wai Y., Schneider, Jingjing, Ro, Sunhee, Cohen, Aileen, Huang, Jane, Dimopoulos, Meletios
Published in Blood (29.10.2020)
Published in Blood (29.10.2020)
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First-line treatment of chronic lymphocytic leukemia with ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab: final analysis of the randomized, phase III iLLUMINATE trial
Moreno, Carol, Greil, Richard, Demirkan, Fatih, Tedeschi, Alessandra, Anz, Bertrand, Larratt, Loree, Simkovic, Martin, Novak, Jan, Strugov, Vladimir, Gill, Devinder, Gribben, John G, Kwei, Kevin, Dai, Sandra, Hsu, Emily, Dean, James P, Flinn, Ian W
Published in Haematologica (Roma) (01.09.2022)
Published in Haematologica (Roma) (01.09.2022)
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Journal Article
Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia
Dimopoulos, Meletios A, Tedeschi, Alessandra, Trotman, Judith, García-Sanz, Ramón, Macdonald, David, Leblond, Veronique, Mahe, Beatrice, Herbaux, Charles, Tam, Constantine, Orsucci, Lorella, Palomba, M. Lia, Matous, Jeffrey V, Shustik, Chaim, Kastritis, Efstathios, Treon, Steven P, Li, Jianling, Salman, Zeena, Graef, Thorsten, Buske, Christian
Published in The New England journal of medicine (21.06.2018)
Published in The New England journal of medicine (21.06.2018)
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Journal Article
Characterization of atrial fibrillation adverse events reported in ibrutinib randomized controlled registration trials
Brown, Jennifer R, Moslehi, Javid, O'Brien, Susan, Ghia, Paolo, Hillmen, Peter, Cymbalista, Florence, Shanafelt, Tait D, Fraser, Graeme, Rule, Simon, Kipps, Thomas J, Coutre, Steven, Dilhuydy, Marie-Sarah, Cramer, Paula, Tedeschi, Alessandra, Jaeger, Ulrich, Dreyling, Martin, Byrd, John C, Howes, Angela, Todd, Michael, Vermeulen, Jessica, James, Danelle F, Clow, Fong, Styles, Lori, Valentino, Rudy, Wildgust, Mark, Mahler, Michelle, Burger, Jan A
Published in Haematologica (Roma) (01.10.2017)
Published in Haematologica (Roma) (01.10.2017)
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Journal Article
Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: extended phase 3 results from RESONATE-2
Barr, Paul M, Robak, Tadeusz, Owen, Carolyn, Tedeschi, Alessandra, Bairey, Osnat, Bartlett, Nancy L, Burger, Jan A, Hillmen, Peter, Coutre, Steven, Devereux, Stephen, Grosicki, Sebastian, McCarthy, Helen, Li, Jianyong, Simpson, David, Offner, Fritz, Moreno, Carol, Zhou, Cathy, Styles, Lori, James, Danelle, Kipps, Thomas J, Ghia, Paolo
Published in Haematologica (Roma) (01.09.2018)
Published in Haematologica (Roma) (01.09.2018)
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Journal Article
Ibrutinib for the treatment of Bing-Neel syndrome: a multicenter study
Castillo, Jorge J., Itchaki, Gilad, Paludo, Jonas, Varettoni, Marzia, Buske, Christian, Eyre, Toby A., Chavez, Julio C., Shain, Kenneth H., Issa, Samar, Palomba, M. Lia, Pasvolsky, Oren, Simpson, David, Talaulikar, Dipti, Tam, Constantine S., Tedeschi, Alessandra, Ansell, Stephen M., Nayak, Lakshmi, Treon, Steven P.
Published in Blood (24.01.2019)
Published in Blood (24.01.2019)
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Journal Article
Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T cell leukemia
Forlani, Greta, Shallak, Mariam, Tedeschi, Alessandra, Cavallari, Ilaria, Marçais, Ambroise, Hermine, Olivier, Accolla, Roberto S
Published in Haematologica (Roma) (01.08.2021)
Published in Haematologica (Roma) (01.08.2021)
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Journal Article
A multicenter total therapy strategy for de novo adult Philadelphia chromosome positive acute lymphoblastic leukemia patients. Final results of the GIMEMA LAL1509 protocol
Chiaretti, Sabina, Ansuinelli, Michela, Vitale, Antonella, Elia, Loredana, Matarazzo, Mabel, Piciocchi, Alfonso, Fazi, Paola, Di Raimondo, Francesco, Santoro, Lidia, Fabbiano, Francesco, Califano, Catello, Martinelli, Giovanni, Ronco, Francesca, Ferrara, Felicetto, Cascavilla, Nicola, Bigazzi, Catia, Tedeschi, Alessandra, Sica, Simona, Di Renzo, Nicola, Melpignano, Angela, Beltrami, Germana, Vignetti, Marco, Foa, Robin
Published in Haematologica (Roma) (01.07.2021)
Published in Haematologica (Roma) (01.07.2021)
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Journal Article
Diagnostics in Waldenström’s macroglobulinemia: a consensus statement of the European Consortium for Waldenström’s Macroglobulinemia
Dogliotti, Irene, Jiménez, Cristina, Varettoni, Marzia, Talaulikar, Dipti, Bagratuni, Tina, Ferrante, Martina, Pérez, José, Drandi, Daniela, Puig, Noemí, Gilestro, Milena, García-Álvarez, María, Owen, Roger, Jurczak, Wojciech, Tedeschi, Alessandra, Leblond, Veronique, Kastritis, Efstathios, Kersten, Marie José, D’Sa, Shirley, Kaščák, Michal, Willenbacher, Wolfgang, Roccaro, Aldo M., Poulain, Stephanie, Morel, Pierre, Kyriakou, Charalampia, Fend, Falko, Vos, Josephine M. I., Dimopoulos, Meletios A., Buske, Christian, Ferrero, Simone, García-Sanz, Ramón
Published in Leukemia (01.02.2023)
Published in Leukemia (01.02.2023)
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Journal Article
Clonal architecture of CXCR4 WHIM‐like mutations in Waldenström Macroglobulinaemia
Xu, Lian, Hunter, Zachary R., Tsakmaklis, Nicholas, Cao, Yang, Yang, Guang, Chen, Jie, Liu, Xia, Kanan, Sandra, Castillo, Jorge J., Tai, Yu‐Tzu, Zehnder, James L., Brown, Jennifer R., Carrasco, Ruben D., Advani, Ranjana, Sabile, Jean M., Argyropoulos, Kimon, Lia Palomba, M., Morra, Enrica, Trojani, Alessandra, Greco, Antonino, Tedeschi, Alessandra, Varettoni, Marzia, Arcaini, Luca, Munshi, Nikhil M., Anderson, Kenneth C., Treon, Steven P.
Published in British journal of haematology (01.03.2016)
Published in British journal of haematology (01.03.2016)
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Journal Article
Central nervous system involvement by Waldenström macroglobulinaemia (Bing‐Neel syndrome): a multi‐institutional retrospective study
Castillo, Jorge J., D'Sa, Shirley, Lunn, Michael P., Minnema, Monique C., Tedeschi, Alessandra, Lansigan, Frederick, Palomba, M. Lia, Varettoni, Marzia, Garcia‐Sanz, Ramon, Nayak, Lakshmi, Lee, Eudocia Q., Rinne, Mikael L., Norden, Andrew D., Ghobrial, Irene M., Treon, Steven P.
Published in British journal of haematology (01.03.2016)
Published in British journal of haematology (01.03.2016)
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Journal Article
Restriction factors in human retrovirus infections and the unprecedented case of CIITA as link of intrinsic and adaptive immunity against HTLV-1
Forlani, Greta, Shallak, Mariam, Ramia, Elise, Tedeschi, Alessandra, Accolla, Roberto S
Published in Retrovirology (29.11.2019)
Published in Retrovirology (29.11.2019)
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Journal Article
A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study
Chiaretti, Sabina, Vitale, Antonella, Vignetti, Marco, Piciocchi, Alfonso, Fazi, Paola, Elia, Loredana, Falini, Brunangelo, Ronco, Francesca, Ferrara, Felicetto, De Fabritiis, Paolo, Luppi, Mario, La Nasa, Giorgio, Tedeschi, Alessandra, Califano, Catello, Fanin, Renato, Dore, Fausto, Mandelli, Franco, Meloni, Giovanna, Foà, Robin
Published in Haematologica (Roma) (01.12.2016)
Published in Haematologica (Roma) (01.12.2016)
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Journal Article
Characterization of zanubrutinib safety and tolerability profile and comparison with ibrutinib safety profile in patients with B-cell malignancies: post-hoc analysis of a large clinical trial safety database
Brown, Jennifer R, Ghia, Paolo, Jurczak, Wojciech, Kahl, Brad S, Lamanna, Nicole, Robak, Tadeusz, Shadman, Mazyar, Tam, Constantine S, Qiu, Lugui, Paik, Jason, Salmi, Tommi, Wang, Liping, Zhang, Jun, Zhang, Meng, Cohen, Aileen, Ma, Han, Tedeschi, Alessandra
Published in Haematologica (Roma) (01.07.2024)
Published in Haematologica (Roma) (01.07.2024)
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Journal Article
Risk of hepatitis B virus reactivation in chronic lymphocytic leukemia patients receiving ibrutinib with or without antiviral prophylaxis. A retrospective multicentric GIMEMA study
Innocenti, Idanna, Reda, Gianluigi, Visentin, Andrea, Coscia, Marta, Motta, Marina, Murru, Roberta, Moia, Riccardo, Gentile, Massimo, Pennese, Elsa, Quaglia, Francesca Maria, Albano, Francesco, Cassin, Ramona, Deodato, Marina, Ielo, Claudia, Frustaci, Anna Maria, Piciocchi, Alfonso, Rughini, Arianna, Arena, Valentina, Di Sevo, Daniela, Tomasso, Annamaria, Autore, Francesco, Del Poeta, Giovanni, Scarfò, Lydia, Mauro, Francesca Romana, Tedeschi, Alessandra, Trentin, Livio, Pompili, Maurizio, Foà, Robin, Ghia, Paolo, Cuneo, Antonio, Laurenti, Luca
Published in Haematologica (Roma) (01.06.2022)
Published in Haematologica (Roma) (01.06.2022)
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Journal Article
HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients
Forlani, Greta, Baratella, Marco, Tedeschi, Alessandra, Pique, Claudine, Jacobson, Steve, Accolla, Roberto S
Published in Frontiers in microbiology (26.04.2019)
Published in Frontiers in microbiology (26.04.2019)
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Journal Article
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)
Baratella, Marco, Forlani, Greta, Raval, Goutham U, Tedeschi, Alessandra, Gout, Olivier, Gessain, Antoine, Tosi, Giovanna, Accolla, Roberto S
Published in PLoS neglected tropical diseases (17.01.2017)
Published in PLoS neglected tropical diseases (17.01.2017)
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