A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization–headspace–gas chromatography–mass spectrometry
Alzaga, Roberto, Ryan, Robert W., Taylor-Worth, Karen, Lipczynski, Andrew M., Szucs, Roman, Sandra, Pat
Published in Journal of pharmaceutical and biomedical analysis (05.11.2007)
Published in Journal of pharmaceutical and biomedical analysis (05.11.2007)
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Development and validation of an automated static headspace gas chromatography–mass spectrometry (SHS-GC–MS) method for monitoring the formation of ethyl methane sulfonate from ethanol and methane sulfonic acid
Jacq, Karine, Delaney, Ed, Teasdale, Andrew, Eyley, Steve, Taylor-Worth, Karen, Lipczynski, Andrew, Reif, Van D., Elder, David P., Facchine, Kevin L., Golec, Simon, Oestrich, Rolf Schulte, Sandra, Pat, David, Frank
Published in Journal of pharmaceutical and biomedical analysis (15.12.2008)
Published in Journal of pharmaceutical and biomedical analysis (15.12.2008)
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A Detailed Study of Sulfonate Ester Formation and Solvolysis Reaction Rates and Application toward Establishing Sulfonate Ester Control in Pharmaceutical Manufacturing Processes
Teasdale, Andrew, Delaney, Edward J, Eyley, Stephen C, Jacq, Karine, Taylor-Worth, Karen, Lipczynski, Andrew, Hoffmann, Wilfried, Reif, Van, Elder, David P, Facchine, Kevin L, Golec, Simon, Schulte Oestrich, Rolf, Sandra, Pat, David, Frank
Published in Organic process research & development (16.07.2010)
Published in Organic process research & development (16.07.2010)
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Mechanism and Processing Parameters Affecting the Formation of Methyl Methanesulfonate from Methanol and Methanesulfonic Acid: An Illustrative Example for Sulfonate Ester Impurity Formation
Teasdale, Andrew, Eyley, Stephen C, Delaney, Ed, Jacq, Karine, Taylor-Worth, Karen, Lipczynski, Andrew, Reif, Van, Elder, David P, Facchine, Kevin L, Golec, Simon, Schulte Oestrich, Rolf, Sandra, Pat, David, Frank
Published in Organic process research & development (15.05.2009)
Published in Organic process research & development (15.05.2009)
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