DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
Rosenthal, Rachel, McGranahan, Nicholas, Herrero, Javier, Taylor, Barry S, Swanton, Charles
Published in Genome Biology (22.02.2016)
Published in Genome Biology (22.02.2016)
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Translational Landscape of the Mammalian Cell Cycle
Stumpf, Craig R, Moreno, Melissa V, Olshen, Adam B, Taylor, Barry S, Ruggero, Davide
Published in Molecular cell (21.11.2013)
Published in Molecular cell (21.11.2013)
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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A, Shah, Ronak H, Dogan, Snjezana, Ricarte-Filho, Julio C, Krishnamoorthy, Gnana P, Xu, Bin, Schultz, Nikolaus, Berger, Michael F, Sander, Chris, Taylor, Barry S, Ghossein, Ronald, Ganly, Ian, Fagin, James A
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer
Lee, Suk Hyung, Hu, Wenhuo, Matulay, Justin T., Silva, Mark V., Owczarek, Tomasz B., Kim, Kwanghee, Chua, Chee Wai, Barlow, LaMont J., Kandoth, Cyriac, Williams, Alanna B., Bergren, Sarah K., Pietzak, Eugene J., Anderson, Christopher B., Benson, Mitchell C., Coleman, Jonathan A., Taylor, Barry S., Abate-Shen, Cory, McKiernan, James M., Al-Ahmadie, Hikmat, Solit, David B., Shen, Michael M.
Published in Cell (05.04.2018)
Published in Cell (05.04.2018)
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Automated network analysis identifies core pathways in glioblastoma
Cerami, Ethan, Demir, Emek, Schultz, Nikolaus, Taylor, Barry S, Sander, Chris
Published in PloS one (12.02.2010)
Published in PloS one (12.02.2010)
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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
Chang, Matthew T, Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H, Chapman, Jocelyn S, Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D, Solit, David B, Olshen, Adam B, Schultz, Nikolaus, Taylor, Barry S
Published in Nature biotechnology (01.02.2016)
Published in Nature biotechnology (01.02.2016)
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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer
Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus
Published in Cancer cell (08.01.2018)
Published in Cancer cell (08.01.2018)
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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
Janjigian, Yelena Y, Maron, Steven B, Chatila, Walid K, Millang, Brittanie, Chavan, Shweta S, Alterman, Carly, Chou, Joanne F, Segal, Michal F, Simmons, Marc Z, Momtaz, Parisa, Shcherba, Marina, Ku, Geoffrey Y, Zervoudakis, Alice, Won, Elizabeth S, Kelsen, David P, Ilson, David H, Nagy, Rebecca J, Lanman, Richard B, Ptashkin, Ryan N, Donoghue, Mark T A, Capanu, Marinela, Taylor, Barry S, Solit, David B, Schultz, Nikolaus, Hechtman, Jaclyn F
Published in The lancet oncology (01.06.2020)
Published in The lancet oncology (01.06.2020)
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Copy number alteration burden predicts prostate cancer relapse
Hieronymus, Haley, Schultz, Nikolaus, Gopalan, Anuradha, Carver, Brett S., Chang, Matthew T., Xiao, Yonghong, Heguy, Adriana, Huberman, Kety, Bernstein, Melanie, Assel, Melissa, Murali, Rajmohan, Vickers, Andrew, Scardino, Peter T., Sander, Chris, Reuter, Victor, Taylor, Barry S., Sawyers, Charles L.
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
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Marked Response of a Hypermutated ACTH-Secreting Pituitary Carcinoma to Ipilimumab and Nivolumab
Lin, Andrew L, Jonsson, Philip, Tabar, Viviane, Yang, T Jonathan, Cuaron, John, Beal, Katherine, Cohen, Marc, Postow, Michael, Rosenblum, Marc, Shia, Jinru, DeAngelis, Lisa M, Taylor, Barry S, Young, Robert J, Geer, Eliza B
Published in The journal of clinical endocrinology and metabolism (01.10.2018)
Published in The journal of clinical endocrinology and metabolism (01.10.2018)
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Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
Audenet, François, Isharwal, Sumit, Cha, Eugene K, Donoghue, Mark T A, Drill, Esther N, Ostrovnaya, Irina, Pietzak, Eugene J, Sfakianos, John P, Bagrodia, Aditya, Murugan, Paari, Dalbagni, Guido, Donahue, Timothy F, Rosenberg, Jonathan E, Bajorin, Dean F, Arcila, Maria E, Hechtman, Jaclyn F, Berger, Michael F, Taylor, Barry S, Al-Ahmadie, Hikmat, Iyer, Gopa, Bochner, Bernard H, Coleman, Jonathan A, Solit, David B
Published in Clinical cancer research (01.02.2019)
Published in Clinical cancer research (01.02.2019)
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Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma
Moore, Amanda R, Ceraudo, Emilie, Sher, Jessica J, Guan, Youxin, Shoushtari, Alexander N, Chang, Matthew T, Zhang, Jenny Q, Walczak, Edward G, Kazmi, Manija A, Taylor, Barry S, Huber, Thomas, Chi, Ping, Sakmar, Thomas P, Chen, Yu
Published in Nature genetics (01.06.2016)
Published in Nature genetics (01.06.2016)
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Integrative Genomic Profiling of Human Prostate Cancer
Taylor, Barry S., Schultz, Nikolaus, Hieronymus, Haley, Gopalan, Anuradha, Xiao, Yonghong, Carver, Brett S., Arora, Vivek K., Kaushik, Poorvi, Cerami, Ethan, Reva, Boris, Antipin, Yevgeniy, Mitsiades, Nicholas, Landers, Thomas, Dolgalev, Igor, Major, John E., Wilson, Manda, Socci, Nicholas D., Lash, Alex E., Heguy, Adriana, Eastham, James A., Scher, Howard I., Reuter, Victor E., Scardino, Peter T., Sander, Chris, Sawyers, Charles L., Gerald, William L.
Published in Cancer cell (13.07.2010)
Published in Cancer cell (13.07.2010)
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The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
Ladanyi, Marc, Bott, Matthew, Brevet, Marie, Taylor, Barry S, Shimizu, Shigeki, Ito, Tatsuo, Wang, Lu, Creaney, Jenette, Lake, Richard A, Zakowski, Maureen F, Reva, Boris, Sander, Chris, Delsite, Robert, Powell, Simon, Zhou, Qin, Shen, Ronglai, Olshen, Adam, Rusch, Valerie
Published in Nature genetics (01.07.2011)
Published in Nature genetics (01.07.2011)
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Genomic Landscape of Uterine Sarcomas Defined Through Prospective Clinical Sequencing
Hensley, Martee L, Chavan, Shweta S, Solit, David B, Murali, Rajmohan, Soslow, Robert, Chiang, Sarah, Jungbluth, Achim A, Bandlamudi, Chaitanya, Srinivasan, Preethi, Tap, William D, Rosenbaum, Evan, Taylor, Barry S, Donoghue, Mark T A, Hyman, David M
Published in Clinical cancer research (15.07.2020)
Published in Clinical cancer research (15.07.2020)
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V⁶⁰⁰EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
Pratilas, Christine A, Taylor, Barry S, Ye, Qing, Viale, Agnes, Sander, Chris, Solit, David B, Rosen, Neal
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets
Gao, Jianjiong, Chang, Matthew T, Johnsen, Hannah C, Gao, Sizhi Paul, Sylvester, Brooke E, Sumer, Selcuk Onur, Zhang, Hongxin, Solit, David B, Taylor, Barry S, Schultz, Nikolaus, Sander, Chris
Published in Genome medicine (23.01.2017)
Published in Genome medicine (23.01.2017)
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Prevalence and Co-Occurrence of Actionable Genomic Alterations in High-Grade Bladder Cancer
IYER, Gopa, AL-AHMADIE, Hikmat, ZABOR, Emily C, JANAKIRAMAN, Manickam, GARCIA-GROSSMAN, Ilana R, HEGUY, Adriana, VIALE, Agnes, BOCHNER, Bernard H, REUTER, Victor E, BAJORIN, Dean F, MILOWSKY, Matthew I, TAYLOR, Barry S, SCHULTZ, Nikolaus, SOLIT, David B, HANRAHAN, Aphrothiti J, OSTROVNAYA, Irina, BALAR, Arjun V, KIM, Philip H, LIN, Oscar, WEINHOLD, Nils, SANDER, Chris
Published in Journal of clinical oncology (01.09.2013)
Published in Journal of clinical oncology (01.09.2013)
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DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors
Mazor, Tali, Pankov, Aleksandr, Johnson, Brett E., Hong, Chibo, Hamilton, Emily G., Bell, Robert J.A., Smirnov, Ivan V., Reis, Gerald F., Phillips, Joanna J., Barnes, Michael J., Idbaih, Ahmed, Alentorn, Agusti, Kloezeman, Jenneke J., Lamfers, Martine L.M., Bollen, Andrew W., Taylor, Barry S., Molinaro, Annette M., Olshen, Adam B., Chang, Susan M., Song, Jun S., Costello, Joseph F.
Published in Cancer cell (14.09.2015)
Published in Cancer cell (14.09.2015)
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