SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
Sanders, David W, Jumper, Chanelle C, Ackerman, Paul J, Bracha, Dan, Donlic, Anita, Kim, Hahn, Kenney, Devin, Castello-Serrano, Ivan, Suzuki, Saori, Tamura, Tomokazu, Tavares, Alexander H, Saeed, Mohsan, Holehouse, Alex S, Ploss, Alexander, Levental, Ilya, Douam, Florian, Padera, Robert F, Levy, Bruce D, Brangwynne, Clifford P
Published in eLife (23.04.2021)
Published in eLife (23.04.2021)
Get full text
Journal Article
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation
Chen, Da-Yuan, Chin, Chue Vin, Kenney, Devin, Tavares, Alexander H., Khan, Nazimuddin, Conway, Hasahn L., Liu, GuanQun, Choudhary, Manish C., Gertje, Hans P., O’Connell, Aoife K., Adams, Scott, Kotton, Darrell N., Herrmann, Alexandra, Ensser, Armin, Connor, John H., Bosmann, Markus, Li, Jonathan Z., Gack, Michaela U., Baker, Susan C., Kirchdoerfer, Robert N., Kataria, Yachana, Crossland, Nicholas A., Douam, Florian, Saeed, Mohsan
Published in Nature (London) (02.03.2023)
Published in Nature (London) (02.03.2023)
Get full text
Journal Article
SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway
Chen, Da-Yuan, Khan, Nazimuddin, Close, Brianna J, Goel, Raghuveera K, Blum, Benjamin, Tavares, Alexander H, Kenney, Devin, Conway, Hasahn L, Ewoldt, Jourdan K, Chitalia, Vipul C, Crossland, Nicholas A, Chen, Christopher S, Kotton, Darrell N, Baker, Susan C, Fuchs, Serge Y, Connor, John H, Douam, Florian, Emili, Andrew, Saeed, Mohsan
Published in Journal of virology (09.09.2021)
Published in Journal of virology (09.09.2021)
Get full text
Journal Article
High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface
Datta, Suprama, Chen, Da-Yuan, Tavares, Alexander H., Reyes-Robles, Tamara, Ryu, Keun Ah, Khan, Nazimuddin, Bechtel, Tyler J., Bertoch, Jayde M., White, Cory H., Hazuda, Daria J., Vora, Kalpit A., Hett, Erik C., Fadeyi, Olugbeminiyi O., Oslund, Rob C., Emili, Andrew, Saeed, Mohsan
Published in Cell chemical biology (19.10.2023)
Published in Cell chemical biology (19.10.2023)
Get full text
Journal Article
Phospholipase D isoforms differentially regulate leukocyte responses to acute lung injury
Abdulnour, Raja‐Elie E., Howrylak, Judie A., Tavares, Alexander H., Douda, David N., Henkels, Karen M., Miller, Taylor E., Fredenburgh, Laura E., Baron, Rebecca M., Gomez‐Cambronero, Julian, Levy, Bruce D.
Published in Journal of leukocyte biology (01.05.2018)
Published in Journal of leukocyte biology (01.05.2018)
Get full text
Journal Article
DNA templates with blocked long 3' end single-stranded overhangs (BL3SSO) promote bona fide Cas9-stimulated homology-directed repair of long transgenes into endogenous gene loci
Bandyopadhyay, Saptaparni, Douglass, Joseph, Kapell, Sebastian, Khan, Nazimuddin, Feitosa-Suntheimer, Fabiana, Klein, Jenny A, Temple, Jasmine, Brown-Culbertson, Jayce, Tavares, Alexander H, Saeed, Mohsan, Lau, Nelson C
Published in G3 : genes - genomes - genetics (07.08.2021)
Published in G3 : genes - genomes - genetics (07.08.2021)
Get full text
Journal Article
Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo
Torchia, James A, Tavares, Alexander H, Carstensen, Laura S, Chen, Da-Yuan, Huang, Jessie, Xiao, Tianshu, Mukherjee, Sonia, Reeves, Patrick M, Tu, Hua, Sluder, Ann E, Chen, Bing, Kotton, Darrell N, Bowen, Richard A, Saeed, Mohsan, Poznansky, Mark C, Freeman, Gordon J
Published in Science advances (09.12.2022)
Published in Science advances (09.12.2022)
Get full text
Journal Article
Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus
Chen, Da-Yuan, Turcinovic, Jacquelyn, Feng, Shuchen, Kenney, Devin J., Chin, Chue Vin, Choudhary, Manish C., Conway, Hasahn L., Semaan, Marc, Close, Brianna J., Tavares, Alexander H., Seitz, Scott, Khan, Nazimuddin, Kapell, Sebastian, Crossland, Nicholas A., Li, Jonathan Z., Douam, Florian, Baker, Susan C., Connor, John H., Saeed, Mohsan
Published in iScience (19.05.2023)
Published in iScience (19.05.2023)
Get full text
Journal Article
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron
Chen, Da-Yuan, Kenney, Devin, Chin, Chue-Vin, Tavares, Alexander H, Khan, Nazimuddin, Conway, Hasahn L, Liu, GuanQun, Choudhary, Manish C, Gertje, Hans P, O'Connell, Aoife K, Kotton, Darrell N, Herrmann, Alexandra, Ensser, Armin, Connor, John H, Bosmann, Markus, Li, Jonathan Z, Gack, Michaela U, Baker, Susan C, Kirchdoerfer, Robert N, Kataria, Yachana, Crossland, Nicholas A, Douam, Florian, Saeed, Mohsan
Published in bioRxiv : the preprint server for biology (10.01.2023)
Published in bioRxiv : the preprint server for biology (10.01.2023)
Get more information
Journal Article
Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes
Levy, Bruce D., Abdulnour, Raja-Elie E., Tavares, Alexander, Brüggemann, Thayse R., Norris, Paul C., Bai, Yan, Ai, Xingbin, Serhan, Charles N.
Published in Journal of allergy and clinical immunology (01.01.2020)
Published in Journal of allergy and clinical immunology (01.01.2020)
Get full text
Journal Article
SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway
Chen, Da-Yuan, Khan, Nazimuddin, Close, Brianna J, Goel, Raghuveera K, Blum, Benjamin, Tavares, Alexander H, Kenney, Devin, Conway, Hasahn L, Ewoldt, Jourdan K, Kapell, Sebastian, Chitalia, Vipul C, Crossland, Nicholas A, Chen, Christopher S, Kotton, Darrell N, Baker, Susan C, Connor, John H, Douam, Florian, Emili, Andrew, Saeed, Mohsan
Published in bioRxiv (28.10.2020)
Published in bioRxiv (28.10.2020)
Get full text
Journal Article
Paper
Cys-LTs’ Pro-phlogistic Lung Actions Are Regulated by Cys-Maresins
Levy, Bruce D., Abdulnour, Raja-Elie E., Tavares, Alexander, Brüggemann, Thayse R., Norris, Paul C., Bai, Yan, Ai, Xingbin, Serhan, Charles N.
Published in Journal of allergy and clinical immunology (14.10.2019)
Published in Journal of allergy and clinical immunology (14.10.2019)
Get full text
Journal Article
Comparing historical-hydrogeomorphological reconstitution and hydrological-hydraulic modelling in the estimation of flood-prone areas – a case study in Central Portugal
Santos, P. P., Tavares, A. O., Andrade, A. I. A. S. S.
Published in Natural hazards and earth system sciences (01.01.2011)
Published in Natural hazards and earth system sciences (01.01.2011)
Get full text
Journal Article
High resolution photocatalytic mapping of SARS-CoV-2 Spike protein-host cell membrane interactions
Datta, Suprama, Tavares, Alexander H, Reyes-Robles, Tamara, Keun Ah Ryu, Khan, Nazimuddin, Bechtel, Tyler J, Bertoch, Jayde M, White, Cory H, Hazuda, Daria J, Vora, Kalpit A, Hett, Erik C, Fadeyi, Olugbeminiyi O, Oslund, Rob C, Mohsan Saeed, Emili, Andrew
Published in bioRxiv (03.09.2022)
Published in bioRxiv (03.09.2022)
Get full text
Paper
SARS-CoV-2 Requires Cholesterol for Viral Entry and Pathological Syncytia Formation
Sanders, David W, Jumper, Chanelle C, Ackerman, Paul J, Bracha, Dan, Donlic, Anita, Hahn, Kim, Kenney, Devin, Castello-Serrano, Ivan, Suzuki, Saori, Tamura, Tomokazu, Tavares, Alexander H, Mohsan Saeed, Holehouse, Alex S, Ploss, Alexander, Levental, Ilya, Douam, Florian, Padera, Robert F, Levy, Bruce D, Brangwynne, Clifford P
Published in bioRxiv (14.12.2020)
Published in bioRxiv (14.12.2020)
Get full text
Paper