Global profiling of co- and post-translationally N-myristoylated proteomes in human cells
Thinon, Emmanuelle, Serwa, Remigiusz A., Broncel, Malgorzata, Brannigan, James A., Brassat, Ute, Wright, Megan H., Heal, William P., Wilkinson, Anthony J., Mann, David J., Tate, Edward W.
Published in Nature communications (26.09.2014)
Published in Nature communications (26.09.2014)
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High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation
Dian, Cyril, Pérez-Dorado, Inmaculada, Rivière, Frédéric, Asensio, Thomas, Legrand, Pierre, Ritzefeld, Markus, Shen, Mengjie, Cota, Ernesto, Meinnel, Thierry, Tate, Edward W., Giglione, Carmela
Published in Nature communications (28.02.2020)
Published in Nature communications (28.02.2020)
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Structural basis for membrane attack complex inhibition by CD59
Couves, Emma C., Gardner, Scott, Voisin, Tomas B., Bickel, Jasmine K., Stansfeld, Phillip J., Tate, Edward W., Bubeck, Doryen
Published in Nature communications (16.02.2023)
Published in Nature communications (16.02.2023)
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Discovery of lipid-mediated protein-protein interactions in living cells using metabolic labeling with photoactivatable clickable probes
Fedoryshchak, Roman O. O., Gorelik, Andrii, Shen, Mengjie, Shchepinova, Maria M. M., Perez-Dorado, Inmaculada, Tate, Edward W. W.
Published in Chemical science (Cambridge) (01.03.2023)
Published in Chemical science (Cambridge) (01.03.2023)
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High‐Throughput Kinetic Analysis for Target‐Directed Covalent Ligand Discovery
Craven, Gregory B., Affron, Dominic P., Allen, Charlotte E., Matthies, Stefan, Greener, Joe G., Morgan, Rhodri M. L., Tate, Edward W., Armstrong, Alan, Mann, David J.
Published in Angewandte Chemie International Edition (04.05.2018)
Published in Angewandte Chemie International Edition (04.05.2018)
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Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development
Broncel, Malgorzata, Serwa, Remigiusz A., Ciepla, Paulina, Krause, Eberhard, Dallman, Margaret J., Magee, Anthony I., Tate, Edward W.
Published in Angewandte Chemie International Edition (11.05.2015)
Published in Angewandte Chemie International Edition (11.05.2015)
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Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
Wright, Megan H., Clough, Barbara, Rackham, Mark D., Rangachari, Kaveri, Brannigan, James A., Grainger, Munira, Moss, David K., Bottrill, Andrew R., Heal, William P., Broncel, Malgorzata, Serwa, Remigiusz A., Brady, Declan, Mann, David J., Leatherbarrow, Robin J., Tewari, Rita, Wilkinson, Anthony J., Holder, Anthony A., Tate, Edward W.
Published in Nature chemistry (01.02.2014)
Published in Nature chemistry (01.02.2014)
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Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases
Kallemeijn, Wouter W, Lueg, Gregor A, Faronato, Monica, Hadavizadeh, Kate, Goya Grocin, Andrea, Song, Ok-Ryul, Howell, Michael, Calado, Dinis P, Tate, Edward W
Published in Cell chemical biology (20.06.2019)
Published in Cell chemical biology (20.06.2019)
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d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition
de Chiara, Cesira, Homšak, Miha, Prosser, Gareth A., Douglas, Holly L., Garza-Garcia, Acely, Kelly, Geoff, Purkiss, Andrew G., Tate, Edward W., de Carvalho, Luiz Pedro S.
Published in Nature chemical biology (01.06.2020)
Published in Nature chemical biology (01.06.2020)
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Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Priyamvada, Lalita, Kallemeijn, Wouter W, Faronato, Monica, Wilkins, Kimberly, Goldsmith, Cynthia S, Cotter, Catherine A, Ojeda, Suany, Solari, Roberto, Moss, Bernard, Tate, Edward W, Satheshkumar, Panayampalli Subbian
Published in PLoS pathogens (01.10.2022)
Published in PLoS pathogens (01.10.2022)
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Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry
Heal, William P, Wright, Megan H, Thinon, Emmanuelle, Tate, Edward W
Published in Nature protocols (01.01.2012)
Published in Nature protocols (01.01.2012)
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Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi, Noura, Welz, Tobias, Robinson, Christopher L., Page, Emma L., Briggs, Deborah A., Stainthorp, Amy K., Reekes, James, Elbe, David A., Straub, Felix, Kallemeijn, Wouter W., Tate, Edward W., Goff, Philip S., Sviderskaya, Elena V., Cantero, Marta, Montoliu, Lluis, Nedelec, Francois, Miles, Amanda K., Bailly, Maryse, Kerkhoff, Eugen, Hume, Alistair N.
Published in Nature communications (13.07.2020)
Published in Nature communications (13.07.2020)
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Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)
Lanyon‐Hogg, Thomas, Ritzefeld, Markus, Zhang, Leran, Andrei, Sebastian A., Pogranyi, Balazs, Mondal, Milon, Sefer, Lea, Johnston, Callum D., Coupland, Claire E., Greenfield, Jake L., Newington, Joshua, Fuchter, Matthew J., Magee, Anthony I., Siebold, Christian, Tate, Edward W.
Published in Angewandte Chemie International Edition (07.06.2021)
Published in Angewandte Chemie International Edition (07.06.2021)
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Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation
Guttery, David S., Poulin, Benoit, Ramaprasad, Abhinay, Wall, Richard J., Ferguson, David J.P., Brady, Declan, Patzewitz, Eva-Maria, Whipple, Sarah, Straschil, Ursula, Wright, Megan H., Mohamed, Alyaa M.A.H., Radhakrishnan, Anand, Arold, Stefan T., Tate, Edward W., Holder, Anthony A., Wickstead, Bill, Pain, Arnab, Tewari, Rita
Published in Cell host & microbe (09.07.2014)
Published in Cell host & microbe (09.07.2014)
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