The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis
Holzer, Guillaume, De Magistris, Paola, Gramminger, Cathrin, Sachdev, Ruchika, Magalska, Adriana, Schooley, Allana, Scheufen, Anja, Lennartz, Birgitt, Tatarek‐Nossol, Marianna, Lue, Hongqi, Linder, Monika I, Kutay, Ulrike, Preisinger, Christian, Moreno‐Andres, Daniel, Antonin, Wolfram
Published in The EMBO journal (01.12.2021)
Published in The EMBO journal (01.12.2021)
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Journal Article
A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly
Andreetto, Erika, Malideli, Eleni, Yan, Li-Mei, Kracklauer, Michael, Farbiarz, Karine, Tatarek-Nossol, Marianna, Rammes, Gerhard, Prade, Elke, Neumüller, Tatjana, Caporale, Andrea, Spanopoulou, Anna, Bakou, Maria, Reif, Bernd, Kapurniotu, Aphrodite
Published in Angewandte Chemie International Edition (26.10.2015)
Published in Angewandte Chemie International Edition (26.10.2015)
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Journal Article
Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association
Andreetto, Erika, Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Frank, Ronald, Kapurniotu, Aphrodite
Published in Angewandte Chemie (International ed.) (12.04.2010)
Published in Angewandte Chemie (International ed.) (12.04.2010)
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Journal Article
An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae
Kralt, Annemarie, Wojtynek, Matthias, Fischer, Jonas S, Agote-Aran, Arantxa, Mancini, Roberta, Dultz, Elisa, Noor, Elad, Uliana, Federico, Tatarek-Nossol, Marianna, Antonin, Wolfram, Onischenko, Evgeny, Medalia, Ohad, Weis, Karsten
Published in eLife (24.08.2022)
Published in eLife (24.08.2022)
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Journal Article
IAPP Mimic Blocks Aβ Cytotoxic Self-Assembly: Cross-Suppression of Amyloid Toxicity of Aβ and IAPP Suggests a Molecular Link between Alzheimer's Disease and Type II Diabetes
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite
Published in Angewandte Chemie International Edition (12.02.2007)
Published in Angewandte Chemie International Edition (12.02.2007)
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Journal Article
Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Rammes, Gerhard, Sibaev, Andrei, Andreetto, Erika, Kracklauer, Michael, Bakou, Maria, Malideli, Eleni, Göke, Burkhard, Schirra, Jörg, Storr, Martin, Kapurniotu, Aphrodite
Published in Angewandte Chemie International Edition (23.09.2013)
Published in Angewandte Chemie International Edition (23.09.2013)
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Journal Article
Design of a Mimic of Nonamyloidogenic and Bioactive Human Islet Amyloid Polypeptide (IAPP) as Nanomolar Affinity Inhibitor of IAPP Cytotoxic Fibrillogenesis
Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Kazantzis, Athanasios, Kapurniotu, Aphrodite
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2006)
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Journal Article
Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic
Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite
Published in Angewandte Chemie International Edition (01.09.2008)
Published in Angewandte Chemie International Edition (01.09.2008)
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Journal Article
Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways
Grudzielanek, Stefan, Velkova, Aleksandra, Shukla, Anuj, Smirnovas, Vytautas, Tatarek-Nossol, Marianna, Rehage, Heinz, Kapurniotu, Aphrodite, Winter, Roland
Published in Journal of molecular biology (06.07.2007)
Published in Journal of molecular biology (06.07.2007)
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Journal Article
Development of Accessible Peptidic Tool Compounds To Study the Phosphatase PTP1B in Intact Cells
Meyer, Christoph, Hoeger, Birgit, Temmerman, Koen, Tatarek-Nossol, Marianna, Pogenberg, Vivian, Bernhagen, Jürgen, Wilmanns, Matthias, Kapurniotu, Aphrodite, Köhn, Maja
Published in ACS chemical biology (21.03.2014)
Published in ACS chemical biology (21.03.2014)
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Journal Article
Eine Hot-Spot-Segmentstrategie zum Entwurf von Mimetika der Kreuzamyloid-Interaktionsflächen als Amyloidinhibitoren
Andreetto, Erika, Malideli, Eleni, Yan, Li-Mei, Kracklauer, Michael, Farbiarz, Karine, Tatarek-Nossol, Marianna, Rammes, Gerhard, Prade, Elke, Neumüller, Tatjana, Caporale, Andrea, Spanopoulou, Anna, Bakou, Maria, Reif, Bernd, Kapurniotu, Aphrodite
Published in Angewandte Chemie (26.10.2015)
Published in Angewandte Chemie (26.10.2015)
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Journal Article
Distinct domains in Ndc1 mediate its interaction with the Nup84 complex and the nuclear membrane
Amm, Ingo, Weberruss, Marion, Hellwig, Andrea, Schwarz, Johannes, Tatarek-Nossol, Marianna, Lüchtenborg, Christian, Kallas, Martina, Brügger, Britta, Hurt, Ed, Antonin, Wolfram
Published in The Journal of cell biology (05.06.2023)
Published in The Journal of cell biology (05.06.2023)
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Journal Article
Blocking Inflammasome Activation Caused by β‑Amyloid Peptide (Aβ) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic
Aftabizadeh, Maryam, Tatarek-Nossol, Marianna, Andreetto, Erika, El Bounkari, Omar, Kipp, Markus, Beyer, Cordian, Latz, Eicke, Bernhagen, Jürgen, Kapurniotu, Aphrodite
Published in ACS chemical neuroscience (21.08.2019)
Published in ACS chemical neuroscience (21.08.2019)
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Journal Article
Hot-Spot-Regionen der Aβ-IAPP-Wechselwirkungsdomänen als hochaffine Bindungsstellen bei Kreuz- und Selbstassoziation
Andreetto, Erika, Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Frank, Ronald, Kapurniotu, Aphrodite
Published in Angewandte Chemie (12.04.2010)
Published in Angewandte Chemie (12.04.2010)
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Journal Article
Amyloid-Kreuzwechselwirkung zur Inhibierung der Proteinaggregation, nicht aber der Proteinfunktion: Inhibierung der Insulinaggregation im nanomolaren Bereich durch ein IAPP-Mimetikum
Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite
Published in Angewandte Chemie (01.09.2008)
Published in Angewandte Chemie (01.09.2008)
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Journal Article
Designed Hairpin Peptides Interfere with Amyloidogenesis Pathways: Fibril Formation and Cytotoxicity Inhibition, Interception of the Preamyloid State
Huggins, Kelly N. L, Bisaglia, Marco, Bubacco, Luigi, Tatarek-Nossol, Marianna, Kapurniotu, Aphrodite, Andersen, Niels H
Published in Biochemistry (Easton) (27.09.2011)
Published in Biochemistry (Easton) (27.09.2011)
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Journal Article
Ein IAPP-Mimetikum blockiert die zytotoxische Aggregation von Aβ - die Kreuzunterdrückung der Amyloidtoxizität von Aβ und IAPP deutet auf einen molekularen Zusammenhang zwischen Alzheimer-Krankheit und Typ-II-Diabetes hin
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite
Published in Angewandte Chemie (12.02.2007)
Published in Angewandte Chemie (12.02.2007)
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Journal Article
Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and A[beta]40
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Rammes, Gerhard, Sibaev, Andrei, Andreetto, Erika, Kracklauer, Michael, Bakou, Maria, Malideli, Eleni, Goke, Burkhard, Schirra, Jörg, Storr, Martin, Kapurniotu, Aphrodite
Published in Angewandte Chemie International Edition (23.09.2013)
Published in Angewandte Chemie International Edition (23.09.2013)
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Journal Article