X-ray Crystallographic Structures of the Escherichia coli Periplasmic Protein FhuD Bound to Hydroxamate-type Siderophores and the Antibiotic Albomycin
Clarke, Teresa E., Braun, Volkmar, Winkelmann, Günther, Tari, Leslie W., Vogel, Hans J.
Published in The Journal of biological chemistry (19.04.2002)
Published in The Journal of biological chemistry (19.04.2002)
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High-affinity binding by the periplasmic iron-binding protein from Haemophilus influenzae is required for acquiring iron from transferrin
Khan, Ali G, Shouldice, Stephen R, Kirby, Shane D, Yu, Rong-hua, Tari, Leslie W, Schryvers, Anthony B
Published in Biochemical journal (01.06.2007)
Published in Biochemical journal (01.06.2007)
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Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae
Mol, Clifford D, Brooun, Alexei, Dougan, Douglas R, Hilgers, Mark T, Tari, Leslie W, Wijnands, Robert A, Knuth, Mark W, McRee, Duncan E, Swanson, Ronald V
Published in Journal of Bacteriology (01.07.2003)
Published in Journal of Bacteriology (01.07.2003)
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Novel Anion-independent Iron Coordination by Members of a Third Class of Bacterial Periplasmic Ferric Ion-binding Proteins
Shouldice, Stephen R., McRee, Duncan E., Dougan, Douglas R., Tari, Leslie W., Schryvers, Anthony B.
Published in The Journal of biological chemistry (18.02.2005)
Published in The Journal of biological chemistry (18.02.2005)
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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity
Tari, Leslie W., Trzoss, Michael, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Nix, Jay, Finn, John
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Structural Basis for Iron Binding and Release by a Novel Class of Periplasmic Iron-Binding Proteins Found in Gram-Negative Pathogens
SHOULDICE, Stephen R, SKENE, Robert J, DOUGAN, Douglas R, SNELL, Gyorgy, MCREE, Duncan E, SCHRYVERS, Anthony B, TARI, Leslie W
Published in Journal of Bacteriology (01.06.2004)
Published in Journal of Bacteriology (01.06.2004)
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Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents
Tari, Leslie W, Li, Xiaoming, Trzoss, Michael, Bensen, Daniel C, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Lee, Suk Joong, Hough, Grayson, Phillipson, Doug, Akers-Rodriguez, Suzanne, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Castellano, Amanda, Locke, Jeff B, Brown-Driver, Vickie, Murphy, Timothy M, Ong, Voon S, Pillar, Chris M, Shinabarger, Dean L, Nix, Jay, Lightstone, Felice C, Wong, Sergio E, Nguyen, Toan B, Shaw, Karen J, Finn, John
Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity
Trzoss, Micheal, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Nelson, Kirk, Brown-Driver, Vickie, Castellano, Amanda, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Finn, John, Tari, Leslie W.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Somoza, John R, Skene, Robert J, Katz, Bradley A, Mol, Clifford, Ho, Joseph D, Jennings, Andy J, Luong, Christine, Arvai, Andrew, Buggy, Joseph J, Chi, Ellen, Tang, Jie, Sang, Bi-Ching, Verner, Erik, Wynands, Robert, Leahy, Ellen M, Dougan, Douglas R, Snell, Gyorgy, Navre, Marc, Knuth, Mark W, Swanson, Ronald V, McRee, Duncan E, Tari, Leslie W
Published in Structure (London) (01.07.2004)
Published in Structure (London) (01.07.2004)
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High Resolution Structure of an Alternate Form of the Ferric Ion Binding Protein from Haemophilus influenzae
Shouldice, Stephen R, Dougan, Douglas R, Skene, Robert J, Tari, Leslie W, McRee, Duncan E, Yu, Rong-hua, Schryvers, Anthony B
Published in The Journal of biological chemistry (28.03.2003)
Published in The Journal of biological chemistry (28.03.2003)
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Crystal Structure of Pasteurella haemolytica Ferric Ion-binding Protein A Reveals a Novel Class of Bacterial Iron-binding Proteins
Shouldice, Stephen R., Dougan, Douglas R., Williams, Pamela A., Skene, Robert J., Snell, Gyorgy, Scheibe, Daniel, Kirby, Shane, Hosfield, David J., McRee, Duncan E., Schryvers, Anthony B., Tari, Leslie W.
Published in The Journal of biological chemistry (17.10.2003)
Published in The Journal of biological chemistry (17.10.2003)
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1195 Discovery of CBO421, a first-in-class drug Fc-conjugate (DFC), targeting CD73 in cancer
Dohrmann, Simon, Levin, James, Dedeic, Nicholas, Almaguer, Amanda, Zuill, Doug, Abelovski, Elizabeth, Grewal, Rajvir, Fortier, Joanne, Zhao, Qiping, Hernandez, Maria, Amundson, Karin, Moniz, Madison, Chen, Hongyuan, Panicker, Dhanya, Lam, Thanh, Brady, Thomas P, Borchardt, Allen, Cole, Jason N, Tari, Leslie W
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Benzimidazole and imidazole inhibitors of histone deacetylases: Synthesis and biological activity
Bressi, Jerome C., Jong, Ron de, Wu, Yiqin, Jennings, Andy J., Brown, Jason W., O’Connell, Shawn, Tari, Leslie W., Skene, Robert J., Vu, Phong, Navre, Marc, Cao, Xiaodong, Gangloff, Anthony R.
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors
Tari, Leslie W., Hoffman, Isaac D., Bensen, Daniel C., Hunter, Michael J., Nix, Jay, Nelson, Kirk J., McRee, Duncan E., Swanson, Ronald V.
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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