Linear ubiquitination in immunity
Shimizu, Yutaka, Taraborrelli, Lucia, Walczak, Henning
Published in Immunological reviews (01.07.2015)
Published in Immunological reviews (01.07.2015)
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The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
Hartwig, Torsten, Montinaro, Antonella, von Karstedt, Silvia, Sevko, Alexandra, Surinova, Silvia, Chakravarthy, Ankur, Taraborrelli, Lucia, Draber, Peter, Lafont, Elodie, Arce Vargas, Frederick, El-Bahrawy, Mona A., Quezada, Sergio A., Walczak, Henning
Published in Molecular cell (16.02.2017)
Published in Molecular cell (16.02.2017)
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LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
Draber, Peter, Kupka, Sebastian, Reichert, Matthias, Draberova, Helena, Lafont, Elodie, de Miguel, Diego, Spilgies, Lisanne, Surinova, Silvia, Taraborrelli, Lucia, Hartwig, Torsten, Rieser, Eva, Martino, Luigi, Rittinger, Katrin, Walczak, Henning
Published in Cell reports (Cambridge) (15.12.2015)
Published in Cell reports (Cambridge) (15.12.2015)
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Journal Article
The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death
Lafont, Elodie, Kantari‐Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen, Sprick, Martin R, Walczak, Henning
Published in The EMBO journal (02.05.2017)
Published in The EMBO journal (02.05.2017)
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Journal Article
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death
Peltzer, Nieves, Rieser, Eva, Taraborrelli, Lucia, Draber, Peter, Darding, Maurice, Pernaute, Barbara, Shimizu, Yutaka, Sarr, Aida, Draberova, Helena, Montinaro, Antonella, Martinez-Barbera, Juan Pedro, Silke, John, Rodriguez, Tristan A, Walczak, Henning
Published in Cell reports (Cambridge) (09.10.2014)
Published in Cell reports (Cambridge) (09.10.2014)
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Journal Article
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
Taraborrelli, Lucia, Peltzer, Nieves, Montinaro, Antonella, Kupka, Sebastian, Rieser, Eva, Hartwig, Torsten, Sarr, Aida, Darding, Maurice, Draber, Peter, Haas, Tobias L, Akarca, Ayse, Marafioti, Teresa, Pasparakis, Manolis, Bertin, John, Gough, Peter J, Bouillet, Philippe, Strasser, Andreas, Leverkus, Martin, Silke, John, Walczak, Henning
Published in Nature communications (25.09.2018)
Published in Nature communications (25.09.2018)
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Mutation position is an important determinant for predicting cancer neoantigens
Capietto, Aude-Hélène, Jhunjhunwala, Suchit, Pollock, Samuel B, Lupardus, Patrick, Wong, Jim, Hänsch, Lena, Cevallos, James, Chestnut, Yajun, Fernandez, Ajay, Lounsbury, Nicolas, Nozawa, Tamaki, Singh, Manmeet, Fan, Zhiyuan, de la Cruz, Cecile C, Phung, Qui T, Taraborrelli, Lucia, Haley, Benjamin, Lill, Jennie R, Mellman, Ira, Bourgon, Richard, Delamarre, Lélia
Published in The Journal of experimental medicine (06.04.2020)
Published in The Journal of experimental medicine (06.04.2020)
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Cancer Cell-Autonomous TRAIL-R Signaling Promotes KRAS-Driven Cancer Progression, Invasion, and Metastasis
von Karstedt, Silvia, Conti, Annalisa, Nobis, Max, Montinaro, Antonella, Hartwig, Torsten, Lemke, Johannes, Legler, Karen, Annewanter, Franka, Campbell, Andrew D., Taraborrelli, Lucia, Grosse-Wilde, Anne, Coy, Johannes F., El-Bahrawy, Mona A., Bergmann, Frank, Koschny, Ronald, Werner, Jens, Ganten, Tom M., Schweiger, Thomas, Hoetzenecker, Konrad, Kenessey, Istvan, Hegedüs, Balazs, Bergmann, Michael, Hauser, Charlotte, Egberts, Jan-Hendrik, Becker, Thomas, Röcken, Christoph, Kalthoff, Holger, Trauzold, Anna, Anderson, Kurt I., Sansom, Owen J., Walczak, Henning
Published in Cancer cell (13.04.2015)
Published in Cancer cell (13.04.2015)
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Journal Article
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
Zinngrebe, Julia, Rieser, Eva, Taraborrelli, Lucia, Peltzer, Nieves, Hartwig, Torsten, Ren, Hongwei, Kovács, Ildikó, Endres, Cornelia, Draber, Peter, Darding, Maurice, von Karstedt, Silvia, Lemke, Johannes, Dome, Balazs, Bergmann, Michael, Ferguson, Brian J, Walczak, Henning
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
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Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer
Taraborrelli, Lucia, Şenbabaoğlu, Yasin, Wang, Lifen, Lim, Junghyun, Blake, Kerrigan, Kljavin, Noelyn, Gierke, Sarah, Scherl, Alexis, Ziai, James, McNamara, Erin, Owyong, Mark, Rao, Shilpa, Calviello, Aslihan Karabacak, Oreper, Daniel, Jhunjhunwala, Suchit, Argiles, Guillem, Bendell, Johanna, Kim, Tae Won, Ciardiello, Fortunato, Wongchenko, Matthew J., de Sauvage, Frederic J., de Sousa e Melo, Felipe, Yan, Yibing, West, Nathaniel R., Murthy, Aditya
Published in Nature communications (23.09.2023)
Published in Nature communications (23.09.2023)
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Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency
Giampazolias, Evangelos, Zunino, Barbara, Dhayade, Sandeep, Bock, Florian, Cloix, Catherine, Cao, Kai, Roca, Alba, Lopez, Jonathan, Ichim, Gabriel, Proïcs, Emma, Rubio-Patiño, Camila, Fort, Loic, Yatim, Nader, Woodham, Emma, Orozco, Susana, Taraborrelli, Lucia, Peltzer, Nieves, Lecis, Daniele, Machesky, Laura, Walczak, Henning, Albert, Matthew L, Milling, Simon, Oberst, Andrew, Ricci, Jean-Ehrland, Ryan, Kevin M, Blyth, Karen, Tait, Stephen W G
Published in Nature cell biology (01.09.2017)
Published in Nature cell biology (01.09.2017)
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Journal Article
Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis
Corrado, Mauro, Mariotti, Francesca R, Trapani, Laura, Taraborrelli, Lucia, Nazio, Francesca, Cianfanelli, Valentina, Soriano, Maria Eugenia, Schrepfer, Emilie, Cecconi, Francesco, Scorrano, Luca, Campello, Silvia
Published in The EMBO journal (15.08.2016)
Published in The EMBO journal (15.08.2016)
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LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Peltzer, Nieves, Darding, Maurice, Montinaro, Antonella, Draber, Peter, Draberova, Helena, Kupka, Sebastian, Rieser, Eva, Fisher, Amanda, Hutchinson, Ciaran, Taraborrelli, Lucia, Hartwig, Torsten, Lafont, Elodie, Haas, Tobias L, Shimizu, Yutaka, Böiers, Charlotta, Sarr, Aida, Rickard, James, Alvarez-Diaz, Silvia, Ashworth, Michael T, Beal, Allison, Enver, Tariq, Bertin, John, Kaiser, William, Strasser, Andreas, Silke, John, Bouillet, Philippe, Walczak, Henning
Published in Nature (London) (01.05.2018)
Published in Nature (London) (01.05.2018)
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Journal Article
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cellᅡ death
Lafont, Elodie, Kantari-Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen, Sprick, Martin R, Walczak, Henning
Published in The EMBO journal (01.05.2017)
Published in The EMBO journal (01.05.2017)
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Journal Article
Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency
Giampazolias, Evangelos, Zunino, Barbara, Dhayade, Sandeep, Bock, Florian, Cloix, Catherine, Cao, Kai, Roca, Alba, Lopez, Jonathan, Ichim, Gabriel, Proïcs, Emma, Rubio-Patiño, Camila, Fort, Loic, Yatim, Nader, Woodham, Emma, Orozco, Susana, Taraborrelli, Lucia, Peltzer, Nieves, Lecis, Daniele, Machesky, Laura, Walczak, Henning, Albert, Matthew L., Milling, Simon, Oberst, Andrew, Ricci, Jean-Ehrland, Ryan, Kevin M., Blyth, Karen, Tait, Stephen W.G.
Published in Nature cell biology (28.08.2017)
Published in Nature cell biology (28.08.2017)
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