The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene
Tanzi, R.E, Petrukhin, K, Chernov, I, Pellequer, J.L, Wasco, W, Ross, B, Romano, D.M, Parano, E, Pavone, L, Brzustowicz, L.M, Devoto, M, Peppercorn, J, Bush, A.I, Sternlieb, I, Pirastu, M, Gusella, J.F, Evgrafov, O, Penchaszadeh, G.K, Honig, B, Edelman, I.S, Soares, M.B, Scheinberg, I.H, Gilliam, T.C
Published in Nature genetics (01.12.1993)
Published in Nature genetics (01.12.1993)
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Journal Article
Mapping, cloning and genetic characterization of the region containing the Wilson disease gene
Gilliam, T.C, Matseoane, D, Parano, E, Sternlieb, I, Evgrafov, O, Boukhgalter, B, Russo, J. J, Brzustowicz, L. M, Wasco, W, Pirastu, M, Penchaszadeh, G. K, Fischer, S. G, Cayanis, E, Scheinberg, I. H, Cao, A, Figus, A. L, Loudianos, J, Vitale, E, Petrukhin, K, Warburton, D, Ott, J, Pavone, L, Devoto, M, Tanzi, R.E, Chernov, I
Published in Nature genetics (01.12.1993)
Published in Nature genetics (01.12.1993)
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Journal Article
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP)
Slunt, H H, Thinakaran, G, Von Koch, C, Lo, A C, Tanzi, R E, Sisodia, S S
Published in The Journal of biological chemistry (28.01.1994)
Published in The Journal of biological chemistry (28.01.1994)
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Journal Article
Familial Alzheimer's chromosome 14 mutations
Wasco, W, Pettingell, W P, Jondro, P D, Schmidt, S D, Gurubhagavatula, S, Rodes, L, DiBlasi, T, Romano, D M, Guenette, S Y, Kovacs, D M
Published in Nature medicine (01.09.1995)
Published in Nature medicine (01.09.1995)
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Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis
Paganoni, Sabrina, Macklin, Eric A, Hendrix, Suzanne, Berry, James D, Elliott, Michael A, Maiser, Samuel, Karam, Chafic, Caress, James B, Owegi, Margaret A, Quick, Adam, Wymer, James, Goutman, Stephen A, Heitzman, Daragh, Heiman-Patterson, Terry, Jackson, Carlayne E, Quinn, Colin, Rothstein, Jeffrey D, Kasarskis, Edward J, Katz, Jonathan, Jenkins, Liberty, Ladha, Shafeeq, Miller, Timothy M, Scelsa, Stephen N, Vu, Tuan H, Fournier, Christina N, Glass, Jonathan D, Johnson, Kristin M, Swenson, Andrea, Goyal, Namita A, Pattee, Gary L, Andres, Patricia L, Babu, Suma, Chase, Marianne, Dagostino, Derek, Dickson, Samuel P, Ellison, Noel, Hall, Meghan, Hendrix, Kent, Kittle, Gale, McGovern, Michelle, Ostrow, Joseph, Pothier, Lindsay, Randall, Rebecca, Shefner, Jeremy M, Sherman, Alexander V, Tustison, Eric, Vigneswaran, Prasha, Walker, Jason, Yu, Hong, Chan, James, Wittes, Janet, Cohen, Joshua, Klee, Justin, Leslie, Kent, Tanzi, Rudolph E, Gilbert, Walter, Yeramian, Patrick D, Schoenfeld, David, Cudkowicz, Merit E
Published in The New England journal of medicine (03.09.2020)
Published in The New England journal of medicine (03.09.2020)
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Clearance of Alzheimer's Aβ Peptide: The Many Roads to Perdition
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Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
Dickerson, B C, Salat, D H, Greve, D N, Chua, E F, Rand-Giovannetti, E, Rentz, D M, Bertram, L, Mullin, K, Tanzi, R E, Blacker, D, Albert, M S, Sperling, R A
Published in Neurology (09.08.2005)
Published in Neurology (09.08.2005)
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Journal Article
Role of common and rare APP DNA sequence variants in Alzheimer disease
Hooli, B V, Mohapatra, G, Mattheisen, M, Parrado, A R, Roehr, J T, Shen, Y, Gusella, J F, Moir, R, Saunders, A J, Lange, C, Tanzi, R E, Bertram, L
Published in Neurology (17.04.2012)
Published in Neurology (17.04.2012)
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Changes in the expression of the Alzheimer’s disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction
Li, A, Zhou, C, Moore, J, Zhang, P, Tsai, T H, Lee, H C, Romano, D M, McKee, M L, Schoenfeld, D A, Serra, M J, Raygor, K, Cantiello, H F, Fujimoto, J G, Tanzi, R E
Published in Current Alzheimer research (01.05.2011)
Published in Current Alzheimer research (01.05.2011)
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Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage
Zhang, Can, Browne, Andrew, Kim, Doo Yeon, Tanzi, Rudolph E
Published in Current Alzheimer research (01.02.2010)
Published in Current Alzheimer research (01.02.2010)
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Journal Article
Modulation of A beta adhesiveness and secretase site cleavage by zinc
A I Bush, W H Pettingell, Jr, M D Paradis, R E Tanzi
Published in The Journal of biological chemistry (22.04.1994)
Published in The Journal of biological chemistry (22.04.1994)
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Journal Article
P4-114 Protection from AD by the XMNI gamma (G) polymorphism may be mediated by interactions between vascular AB1-42 and methemoglobin
Hill, William D., Perry, R.T., Wiener, H., Harrell, L., Gearha, D.A., Ozcan, O., Blacker, D., Tanzi, R.E., McInnis, M.G., Bassett, S.S.D., Go, R.C.P.
Published in Neurobiology of aging (01.07.2004)
Published in Neurobiology of aging (01.07.2004)
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Journal Article
Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site
Abbenante, G., Kovacs, D.M., Leung, D.L., Craik, D.J., Tanzi, R.E., Fairlie, D.P.
Published in Biochemical and biophysical research communications (05.02.2000)
Published in Biochemical and biophysical research communications (05.02.2000)
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Journal Article
The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21
St George-Hyslop, Peter H., Tanzi, Rudolph E., Polinsky, Ronald J., Haines, Jonathan L., Nee, Linda, Watkins, Paul C., Myers, Richard H., Feldman, Robert G., Pollen, Daniel, Drachman, David, Growdon, John, Bruni, Amalia, Foncin, Jean-Francois, Salmon, Denise, Frommelt, Peter, Amaducci, Luigi, Sorbi, Sandro, Piacentini, Silva, Stewart, Gordon D., Hobbs, Wendy J., Conneally, P. Michael, Gusella, James F.
Published in Science (American Association for the Advancement of Science) (20.02.1987)
Published in Science (American Association for the Advancement of Science) (20.02.1987)
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Immunohistochemical and in situ analysis of amyloid precursor-like protein-1 and amyloid precursor-like protein-2 expression in Alzheimer disease and aged control brains
McNamara, Megan J, Ruff, Christian T, Wasco, Wilma, Tanzi, R.E, Thinakaran, Gopal, Hyman, Bradley T
Published in Brain research (31.08.1998)
Published in Brain research (31.08.1998)
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