Low Levels of Brain-Derived Neurotrophic Factor Trigger Self-aggregated Amyloid β-Induced Neuronal Cell Death in an Alzheimer’s Cell Model
Tagai, Nozomi, Tanaka, Ayako, Sato, Akira, Uchiumi, Fumiaki, Tanuma, Sei-ichi
Published in Biological & pharmaceutical bulletin (01.07.2020)
Published in Biological & pharmaceutical bulletin (01.07.2020)
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Journal Article
Differences in the effects of four TRPV1 channel antagonists on lipopolysaccharide-induced cytokine production and COX-2 expression in murine macrophages
Ninomiya, Yuki, Tanuma, Sei-ichi, Tsukimoto, Mitsutoshi
Published in Biochemical and biophysical research communications (11.03.2017)
Published in Biochemical and biophysical research communications (11.03.2017)
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Journal Article
Antinociceptive activity of the novel RAGE inhibitor, papaverine, in a mouse model of chronic inflammatory pain
Yoshizawa, Kazumi, Takeuchi, Kota, Nakamura, Toka, Ukai, Saki, Takahashi, Yukino, Sato, Akira, Takasawa, Ryoko, Tanuma, Sei‐ichi
Published in Synapse (New York, N.Y.) (01.03.2021)
Published in Synapse (New York, N.Y.) (01.03.2021)
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Journal Article
Effect of the natural compound trans‑resveratrol on human MCM4 gene transcription
Uchiumi, Fumiaki, Katsuda, Chihiro, Akui, Motohiro, Kusaka, Monami, Tanaka, Marie, Asai, Masashi, Tanuma, Sei-Ichi
Published in Oncology reports (01.07.2020)
Published in Oncology reports (01.07.2020)
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Journal Article
Discovery of a new type of scaffold for the creation of novel tyrosinase inhibitors
Oyama, Takahiro, Takahashi, Satoshi, Yoshimori, Atsushi, Yamamoto, Tetsuya, Sato, Akira, Kamiya, Takanori, Abe, Hideaki, Abe, Takehiko, Tanuma, Sei-ichi
Published in Bioorganic & medicinal chemistry (15.09.2016)
Published in Bioorganic & medicinal chemistry (15.09.2016)
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Journal Article
Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors
Asawa, Yasunobu, Katsuragi, Kiyotaka, Sato, Akira, Yoshimori, Atsushi, Tanuma, Sei-ichi, Nakamura, Hiroyuki
Published in Bioorganic & medicinal chemistry (01.07.2019)
Published in Bioorganic & medicinal chemistry (01.07.2019)
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Journal Article
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma
Nomura, Miyuki, Ohuchi, Mai, Sakamoto, Yoshimi, Kudo, Kei, Yaku, Keisuke, Soga, Tomoyoshi, Sugiura, Yuki, Morita, Mami, Hayashi, Kayoko, Miyahara, Shuko, Sato, Taku, Yamashita, Yoji, Ito, Shigemi, Kikuchi, Naohiko, Sato, Ikuro, Saito, Rintaro, Yaegashi, Nobuo, Fukuhara, Tatsuro, Yamada, Hidekazu, Shima, Hiroshi, Nakayama, Keiichi I., Hirao, Atsushi, Kawasaki, Kenta, Arai, Yoichi, Akamatsu, Shusuke, Tanuma, Sei-ichi, Sato, Toshiro, Nakagawa, Takashi, Tanuma, Nobuhiro
Published in Nature communications (13.12.2023)
Published in Nature communications (13.12.2023)
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A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways
Okazawa, Miwa, Oyama, Takahiro, Abe, Hideaki, Yamazaki, Hiroaki, Yoshimori, Atsushi, Tsukimoto, Mitsutoshi, Yoshizawa, Kazumi, Takao, Koichi, Sugita, Yoshiaki, Kamiya, Takanori, Uchiumi, Fumiaki, Sakagami, Hiroshi, Abe, Takehiko, Tanuma, Sei-ichi
Published in Biochemical and biophysical research communications (20.08.2021)
Published in Biochemical and biophysical research communications (20.08.2021)
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Journal Article
Characterization of the human zinc finger nfx‑1‑type containing 1 encoding ZNFX1 gene and its response to 12‑O‑tetradecanoyl‑13‑acetate in HL‑60 cells
Hamada, Hiroshi, Yamamura, Mayu, Ohi, Hiroto, Kobayashi, Yota, Niwa, Kuniyoshi, Oyama, Takahiro, Mano, Yasunari, Asai, Masashi, Tanuma, Sei-Ichi, Uchiumi, Fumiaki
Published in International journal of oncology (01.10.2019)
Published in International journal of oncology (01.10.2019)
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Journal Article
Trimebutine attenuates high mobility group box 1–receptor for advanced glycation end-products inflammatory signaling pathways
Nakajima, Shingo, Ogawa, Natsumi, Yokoue, Natsuki, Tachibana, Haruki, Tamada, Kenya, Okazawa, Miwa, Sato, Akira, Oyama, Takahiro, Abe, Hideaki, Kamiya, Takanori, Yoshimori, Atsushi, Yoshizawa, Kazumi, Inoue, Shigeaki, Yokomizo, Takehiko, Uchiumi, Fumiaki, Abe, Takehiko, Tanuma, Sei-ichi
Published in Biochemical and biophysical research communications (17.12.2020)
Published in Biochemical and biophysical research communications (17.12.2020)
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Journal Article
DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis
Mizuta, Ryushin, Araki, Shinsuke, Furukawa, Makoto, Furukawa, Yuki, Ebara, Syota, Shiokawa, Daisuke, Hayashi, Katsuhiko, Tanuma, Sei-ichi, Kitamura, Daisuke
Published in PloS one (02.12.2013)
Published in PloS one (02.12.2013)
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Journal Article
Passion fruit seed extract protects beta‐amyloid‐induced neuronal cell death in a differentiated human neuroblastoma SH‐SY5Y cell model
Sato, Akira, Tagai, Nozomi, Ogino, Yoko, Uozumi, Haruka, Kawakami, Shinpei, Yamamoto, Takayuki, Tanuma, Sei‐ichi, Maruki‐Uchida, Hiroko, Mori, Sadao, Morita, Minoru
Published in Food science & nutrition (01.05.2022)
Published in Food science & nutrition (01.05.2022)
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