Targeting MCL-1 protein to treat cancer: opportunities and challenges
Tantawy, Shady I., Timofeeva, Natalia, Sarkar, Aloke, Gandhi, Varsha
Published in Frontiers in oncology (31.07.2023)
Published in Frontiers in oncology (31.07.2023)
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Journal Article
Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability
Tantawy, Shady I, Timofeeva, Natalia, Hernandez, Ana, Sarkar, Aloke, Gandhi, Varsha
Published in Oncotarget (21.06.2023)
Published in Oncotarget (21.06.2023)
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Journal Article
Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies
Tantawy, Shady I, Sarkar, Aloke, Hubner, Stefan, Tan, Zhi, Wierda, William G, Eldeib, Abdelraouf, Zhang, Shuxing, Kornblau, Steven, Gandhi, Varsha
Published in Clinical cancer research (17.01.2023)
Published in Clinical cancer research (17.01.2023)
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Journal Article
Transcriptomic and proteomic differences in BTK-WT and BTK-mutated CLL and their changes during therapy with pirtobrutinib
Aslan, Burcu, Manyam, Ganiraju, Iles, Lakesla R., Tantawy, Shady I., Desikan, Sai Prasad, Wierda, William G., Gandhi, Varsha
Published in Blood advances (10.09.2024)
Published in Blood advances (10.09.2024)
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Journal Article
Pharmacological Profiling of Cells from Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Pirtobrutinib
Tantawy, Shady I., Aslan, Burcu, Chen, Lisa S, Iles, Lakesla, Thompson, Philip A., Jain, Nitin, Wierda, William G., Gandhi, Varsha
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Characterization and Preclinical Evaluation of AS-1763, an Oral, Potent and Selective Noncovalent BTK Inhibitor, in Chronic Lymphocytic Leukemia
Tantawy, Shady I., Timofeeva, Natalia, Fujiwara, Hitomi, Hatakeyama, Mariko, Herrera, Breana, Loza, Lizbeth, Asami, Tokiko, Ohmoto, Hiroshi, Miyamoto, Kyoko, Nishioka, Yu, Arimura, Akinori, Sawa, Masaaki, Jain, Nitin, Gandhi, Varsha
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Genomic Evolution and Resistance during Pirtobrutinib Therapy in Covalent BTK-Inhibitor (cBTKi) Pre-Treated Chronic Lymphocytic Leukemia Patients: Updated Analysis from the BRUIN Study
Brown, Jennifer R., Desikan, Sai Prasad, Nguyen, Bastien, Won, Helen, Tantawy, Shady I., McNeely, Samuel, Marella, Narasimha, Ebata, Kevin, Woyach, Jennifer A., Patel, Krish, Tam, Constantine S., Eyre, Toby A., Cheah, Chan Y., Shah, Nirav N., Ghia, Paolo, Jurczak, Wojciech, Balbas, Minna, Nair, Binoj, Abada, Paolo, Wang, Chunxiao, Wang, Ying (Denise), Roeker, Lindsey E., Gandhi, Varsha, Wierda, William G.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Phosphatidylserine and the thrombin-antithrombin complex as markers for hypercoagulability in Egyptian beta-thalassemia patients
Sadek, Marwa, Ahmed, Amal, El Fiky, Samar, Tantawy, Shady, Hassan, Amany
Published in The Egyptian journal of haematology : the official journal of the Egyptian Society of Haematology (01.07.2022)
Published in The Egyptian journal of haematology : the official journal of the Egyptian Society of Haematology (01.07.2022)
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Journal Article