A Toll-Like Receptor 7, 8, and 9 Antagonist Inhibits Th1 and Th17 Responses and Inflammasome Activation in a Model of IL-23-Induced Psoriasis
Jiang, Weiwen, Zhu, Fu-Gang, Bhagat, Lakshmi, Yu, Dong, Tang, Jimmy X., Kandimalla, Ekambar R., La Monica, Nicola, Agrawal, Sudhir
Published in Journal of investigative dermatology (01.07.2013)
Published in Journal of investigative dermatology (01.07.2013)
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A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice
Zhu, Fu-Gang, Jiang, Weiwen, Bhagat, Lakshmi, Wang, Daqing, Yu, Dong, Tang, Jimmy X., Kandimalla, Ekambar R., La Monica, Nicola, Agrawal, Sudhir
Published in Autoimmunity (Chur, Switzerland) (01.11.2013)
Published in Autoimmunity (Chur, Switzerland) (01.11.2013)
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Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8
Lan, Tao, Kandimalla, Ekambar R, Yu, Dong, Bhagat, Lakshmi, Li, Yukui, Wang, Daqing, Zhu, FuGang, Tang, Jimmy X, Putta, Mallikarjuna R, Cong, YanPing, Trombino, Anthony F, Sullivan, Tim, Agrawal, Sudhir
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2007)
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Immunomodulatory Oligonucleotides Containing a Cytosine-Phosphate-2′-Deoxy-7-Deazaguanosine Motif as Potent Toll-Like Receptor 9 Agonists
Kandimalla, Ekambar R., Bhagat, Lakshmi, Li, Yukui, Yu, Dong, Wang, Daqing, Cong, Yan-Ping, Song, Sam S., Tang, Jimmy X., Sullivan, Tim, Agrawal, Sudhir, Zamecnik, Paul C.
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2005)
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Agonists of Toll-like Receptor 9 Containing Synthetic Dinucleotide Motifs
Yu, Dong, Putta, Mallikarjuna R, Bhagat, Lakshmi, Li, Yukui, Zhu, FuGang, Wang, Daqing, Tang, Jimmy X, Kandimalla, Ekambar R, Agrawal, Sudhir
Published in Journal of medicinal chemistry (13.12.2007)
Published in Journal of medicinal chemistry (13.12.2007)
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A Dinucleotide Motif in Oligonucleotides Shows Potent Immunomodulatory Activity and Overrides Species-Specific Recognition Observed with CpG Motif
Kandimalla, Ekambar R., Bhagat, Lakshmi, Zhu, Fu-Gang, Yu, Dong, Cong, Yan-Ping, Wang, Daqing, Tang, Jimmy X., Tang, Jin-Yan, Knetter, Cathrine F., Lien, Egil, Agrawal, Sudhir
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
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Journal Article
Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9
Wang, Daqing, Bhagat, Lakshmi, Yu, Dong, Zhu, Fu-Gang, Tang, Jimmy X, Kandimalla, Ekambar R, Agrawal, Sudhir
Published in Journal of medicinal chemistry (22.01.2009)
Published in Journal of medicinal chemistry (22.01.2009)
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Novel Oligonucleotides Containing Two 3′-Ends Complementary to Target mRNA Show Optimal Gene-Silencing Activity
Bhagat, Lakshmi, Putta, Mallikarjuna Reddy, Wang, Daqing, Yu, Dong, Lan, Tao, Jiang, Weiwen, Sun, Zhenhua, Wang, Hao, Tang, Jimmy X, La Monica, Nicola, Kandimalla, Ekambar R, Agrawal, Sudhir
Published in Journal of medicinal chemistry (28.04.2011)
Published in Journal of medicinal chemistry (28.04.2011)
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Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo
Lan, Tao, Wang, Daqing, Bhagat, Lakshmi, Philbin, Victoria J, Yu, Dong, Tang, Jimmy X, Putta, Mallikarjuna R, Sullivan, Tim, La Monica, Nicola, Kandimalla, Ekambar R, Agrawal, Sudhir
Published in Organic & biomolecular chemistry (14.02.2013)
Published in Organic & biomolecular chemistry (14.02.2013)
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Synthesis and immunological activities of novel agonists of toll-like receptor 9
Struthers, Mary, Bett, Andrew J., Wisniewski, Thomas, Dubey, Sheri A., Precopio, Melissa, Jiang, Weiwen, Sun, Zhenhua, Wang, Hao, Nowak, Ireneusz, Putta, Mallikarjuna R., Yu, Dong, Tang, Jimmy X., Kandimalla, Ekambar R., Agrawal, Sudhir, Casimiro, Danilo R.
Published in Cellular immunology (2010)
Published in Cellular immunology (2010)
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A novel polymer-supported sulfur-transfer reagent for the synthesis of phosphorothioates
Zhang, Zhaoda, Han, Yongxin, Tang, Jimmy X, Tang, Jin-yan
Published in Tetrahedron letters (10.06.2002)
Published in Tetrahedron letters (10.06.2002)
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Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivoElectronic supplementary information (ESI) available: Three tables of analytical data and four figures. See DOI: 10.1039/c2ob26946e
Lan, Tao, Wang, Daqing, Bhagat, Lakshmi, Philbin, Victoria J, Yu, Dong, Tang, Jimmy X, Putta, Mallikarjuna R, Sullivan, Tim, La Monica, Nicola, Kandimalla, Ekambar R, Agrawal, Sudhir
Year of Publication 17.01.2013
Year of Publication 17.01.2013
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Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitroand in vivo
Lan, Tao, Wang, Daqing, Bhagat, Lakshmi, Philbin, Victoria J, Yu, Dong, Tang, Jimmy X, Putta, Mallikarjuna R, Sullivan, Tim, La Monica, Nicola, Kandimalla, Ekambar R, Agrawal, Sudhir
Published in Organic & biomolecular chemistry (01.01.2013)
Published in Organic & biomolecular chemistry (01.01.2013)
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IMO-4200, a Novel TLR7 and TLR8 Dual Agonist, Enhances Antitumor Effect of Ofatumumab, Rituximab and Cytotoxics in Preclinical Models of Hematological Malignancies
Wang, Daqing, Precopio, Melissa, Reardon, Michael J, Lan, Tao, Tang, Jimmy X, Kandimalla, Ekambar R, Bexon, Alice, Monica, Nicola La, Agrawal, Sudhir
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Antitumor Activity of An RNA-Based Agonist of TLR7 and 8 In Preclinical Models of Hematological Malignancies
Wang, Daqing, Precopio, Melissa, Reardon, Michael, Lan, Tao, Tang, Jimmy X, Kandimalla, Ekambar R, La Monica, Nicola, Agrawal, Sudhir
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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