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Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
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Published in Nature communications (17.06.2019)
Published in Nature communications (17.06.2019)
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New Non-Peptide Endothelin-A Receptor Antagonists: Synthesis, Biological Properties, and Structure−Activity Relationships of 5-(Dimethylamino)-N-pyridyl-, -N-pyrimidinyl-, -N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides
Bradbury, Robert H, Bath, Colin, Butlin, Roger J, Dennis, Michael, Heys, Christine, Hunt, Sarah J, James, Roger, Mortlock, Andrew A, Sumner, Neil F, Tang, Eric K, Telford, Berwick, Whiting, Elaine, Wilson, Campbell
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Cell-based assay for functional screening of compounds active at the human endothelin A receptor
McLean, J S, Kruger, H, Swift, D, Tang, E K, Brennand, J C
Published in Journal of cardiovascular pharmacology (01.12.1995)
Published in Journal of cardiovascular pharmacology (01.12.1995)
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N-methyl-2-[4-(2-methylpropyl)phenyl]-3-(3-methoxy-5-methylpyrazin-2-ylsulfamoyl)benzamide ; One of a class of novel benzenesulphonamides which are orally-active, ETA-Selective endothelin antagonists
MORTLOCK, A. A, BATH, C, WRIGHT, N. D, BUTLIN, R. J, HEYS, C, HUNT, S. J, REID, A. C, SUMNER, N. F, TANG, E. K, WHITING, E, WILSON, C
Published in Bioorganic & medicinal chemistry letters (01.06.1997)
Published in Bioorganic & medicinal chemistry letters (01.06.1997)
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N-Methyl-2-[4-(2-methylpropyl)phenyl]-3-(3-methoxy-5-methylpyrazin-2-ylsulfamoyl)benzamide; one of a class of novel benzenesulphonamides which are orally-active, ET A-selective endothelin antagonists
Mortlock, Andrew A., Bath, Colin, Butlin, Roger J., Heys, Christine, Hunt, Sarah J., Reid, Alan C., Sumner, Neil F., Tang, Eric K., Whiting, Elaine, Wilson, Campbell, Wright, Nicola D.
Published in Bioorganic & medicinal chemistry letters (1997)
Published in Bioorganic & medicinal chemistry letters (1997)
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Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase
Houslay, M D, Griffiths, S L, Horton, Y M, Livingstone, C, Lobban, M, Macdonald, F, Morris, N, Pryde, J, Scotland, G, Shakur, Y
Published in Biochemical Society transactions (01.02.1992)
Published in Biochemical Society transactions (01.02.1992)
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