Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction
Shi, Lihong, Cui, Shuaiying, Engel, James D, Tanabe, Osamu
Published in Nature medicine (01.03.2013)
Published in Nature medicine (01.03.2013)
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Journal Article
Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective
Kuriyama, Shinichi, Metoki, Hirohito, Kikuya, Masahiro, Obara, Taku, Ishikuro, Mami, Yamanaka, Chizuru, Nagai, Masato, Matsubara, Hiroko, Kobayashi, Tomoko, Sugawara, Junichi, Tamiya, Gen, Hozawa, Atsushi, Nakaya, Naoki, Tsuchiya, Naho, Nakamura, Tomohiro, Narita, Akira, Kogure, Mana, Hirata, Takumi, Tsuji, Ichiro, Nagami, Fuji, Fuse, Nobuo, Arai, Tomohiko, Kawaguchi, Yoshio, Higuchi, Shinichi, Sakaida, Masaki, Suzuki, Yoichi, Osumi, Noriko, Nakayama, Keiko, Ito, Kiyoshi, Egawa, Shinichi, Chida, Koichi, Kodama, Eiichi, Kiyomoto, Hideyasu, Ishii, Tadashi, Tsuboi, Akito, Tomita, Hiroaki, Taki, Yasuyuki, Kawame, Hiroshi, Suzuki, Kichiya, Ishii, Naoto, Ogishima, Soichi, Mizuno, Satoshi, Takai-Igarashi, Takako, Minegishi, Naoko, Yasuda, Jun, Igarashi, Kazuhiko, Shimizu, Ritsuko, Nagasaki, Masao, Tanabe, Osamu, Koshiba, Seizo, Hashizume, Hiroaki, Motohashi, Hozumi, Tominaga, Teiji, Ito, Sadayoshi, Tanno, Kozo, Sakata, Kiyomi, Shimizu, Atsushi, Hitomi, Jiro, Sasaki, Makoto, Kinoshita, Kengo, Tanaka, Hiroshi, Kobayashi, Tadao, Kure, Shigeo, Yaegashi, Nobuo, Yamamoto, Masayuki
Published in International journal of epidemiology (01.02.2020)
Published in International journal of epidemiology (01.02.2020)
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Journal Article
Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development
Liu, Jinhua, Li, Yapu, Tong, Jingyuan, Gao, Jie, Guo, Qing, Zhang, Lingling, Wang, Bingrui, Zhao, Hui, Wang, Hongtao, Jiang, Erlie, Kurita, Ryo, Nakamura, Yukio, Tanabe, Osamu, Engel, James Douglas, Bresnick, Emery H, Zhou, Jiaxi, Shi, Lihong
Published in Nature communications (22.10.2018)
Published in Nature communications (22.10.2018)
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Journal Article
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation
Keleku-Lukwete, Nadine, Suzuki, Mikiko, Otsuki, Akihito, Tsuchida, Kouhei, Katayama, Saori, Hayashi, Makiko, Naganuma, Eriko, Moriguchi, Takashi, Tanabe, Osamu, Engel, James Douglas, Imaizumi, Masue, Yamamoto, Masayuki
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2015)
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Journal Article
FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
Liu, Fei, Lee, Jae Y., Wei, Huijun, Tanabe, Osamu, Engel, James D., Morrison, Sean J., Guan, Jun-Lin
Published in Blood (02.12.2010)
Published in Blood (02.12.2010)
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Journal Article
Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis
Yamauchi, Takafumi, Ochi, Daisuke, Matsukawa, Naomi, Saigusa, Daisuke, Ishikuro, Mami, Obara, Taku, Tsunemoto, Yoshiki, Kumatani, Satsuki, Yamashita, Riu, Tanabe, Osamu, Minegishi, Naoko, Koshiba, Seizo, Metoki, Hirohito, Kuriyama, Shinichi, Yaegashi, Nobuo, Yamamoto, Masayuki, Nagasaki, Masao, Hiyama, Satoshi, Sugawara, Junichi
Published in Scientific reports (07.09.2021)
Published in Scientific reports (07.09.2021)
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Journal Article
Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery
Saigusa, Daisuke, Okamura, Yasunobu, Motoike, Ikuko N, Katoh, Yasutake, Kurosawa, Yasuhiro, Saijyo, Reina, Koshiba, Seizo, Yasuda, Jun, Motohashi, Hozumi, Sugawara, Junichi, Tanabe, Osamu, Kinoshita, Kengo, Yamamoto, Masayuki
Published in PloS one (31.08.2016)
Published in PloS one (31.08.2016)
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Journal Article
Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells
Matsuda, Yukiko, Uchimura, Arikuni, Satoh, Yasunari, Kato, Naohiro, Toshishige, Masaaki, Kajimura, Junko, Hamasaki, Kanya, Yoshida, Kengo, Hayashi, Tomonori, Noda, Asao, Tanabe, Osamu
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2023)
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Journal Article
Genome-wide association study identifies new loci for albuminuria in the Japanese population
Okuda, Hiroshi, Okamoto, Koji, Abe, Michiaki, Ishizawa, Kota, Makino, Satoshi, Tanabe, Osamu, Sugawara, Junichi, Hozawa, Atsushi, Tanno, Kozo, Sasaki, Makoto, Tamiya, Gen, Yamamoto, Masayuki, Ito, Sadayoshi, Ishii, Tadashi
Published in Clinical and experimental nephrology (01.08.2020)
Published in Clinical and experimental nephrology (01.08.2020)
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Journal Article
Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project
Koshiba, Seizo, Motoike, Ikuko, Saigusa, Daisuke, Inoue, Jin, Shirota, Matsuyuki, Katoh, Yasutake, Katsuoka, Fumiki, Danjoh, Inaho, Hozawa, Atsushi, Kuriyama, Shinichi, Minegishi, Naoko, Nagasaki, Masao, Takai‐Igarashi, Takako, Ogishima, Soichi, Fuse, Nobuo, Kure, Shigeo, Tamiya, Gen, Tanabe, Osamu, Yasuda, Jun, Kinoshita, Kengo, Yamamoto, Masayuki
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.06.2018)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.06.2018)
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Journal Article
The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation
Lee, Mary P., Tanabe, Osamu, Shi, Lihong, Jearawiriyapaisarn, Natee, Lucas, Daniel, Engel, James Douglas
Published in Blood (07.12.2017)
Published in Blood (07.12.2017)
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Journal Article
Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare
Yasuda, Jun, Kinoshita, Kengo, Katsuoka, Fumiki, Danjoh, Inaho, Sakurai-Yageta, Mika, Motoike, Ikuko N, Kuroki, Yoko, Saito, Sakae, Kojima, Kaname, Shirota, Matsuyuki, Saigusa, Daisuke, Otsuki, Akihito, Kawashima, Junko, Yamaguchi-Kabata, Yumi, Tadaka, Shu, Aoki, Yuichi, Mimori, Takahiro, Kumada, Kazuki, Inoue, Jin, Makino, Satoshi, Kuriki, Miho, Fuse, Nobuo, Koshiba, Seizo, Tanabe, Osamu, Nagasaki, Masao, Tamiya, Gen, Shimizu, Ritsuko, Takai-Igarashi, Takako, Ogishima, Soichi, Hozawa, Atsushi, Kuriyama, Shinichi, Sugawara, Junichi, Tsuboi, Akito, Kiyomoto, Hideyasu, Ishii, Tadashi, Tomita, Hiroaki, Minegishi, Naoko, Suzuki, Yoichi, Suzuki, Kichiya, Kawame, Hiroshi, Tanaka, Hiroshi, Taki, Yasuyuki, Yaegashi, Nobuo, Kure, Shigeo, Nagami, Fuji, Kosaki, Kenjiro, Sutoh, Yoichi, Hachiya, Tsuyoshi, Shimizu, Atsushi, Sasaki, Makoto, Yamamoto, Masayuki
Published in Journal of biochemistry (Tokyo) (01.02.2019)
Published in Journal of biochemistry (Tokyo) (01.02.2019)
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Journal Article
TRIM28 is essential for erythroblast differentiation in the mouse
Hosoya, Tomonori, Clifford, Mary, Losson, Régine, Tanabe, Osamu, Engel, James Douglas
Published in Blood (28.11.2013)
Published in Blood (28.11.2013)
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Journal Article
Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals
Yamaguchi-Kabata, Yumi, Yasuda, Jun, Uruno, Akira, Shimokawa, Kazuro, Koshiba, Seizo, Suzuki, Yoichi, Fuse, Nobuo, Kawame, Hiroshi, Tadaka, Shu, Nagasaki, Masao, Kojima, Kaname, Katsuoka, Fumiki, Kumada, Kazuki, Tanabe, Osamu, Tamiya, Gen, Yaegashi, Nobuo, Kinoshita, Kengo, Yamamoto, Masayuki, Kure, Shigeo
Published in Human genetics (01.04.2019)
Published in Human genetics (01.04.2019)
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Journal Article
Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model
Suzuki, Mikiko, Yamazaki, Hiromi, Mukai, Harumi Y., Motohashi, Hozumi, Shi, Lihong, Tanabe, Osamu, Engel, James Douglas, Yamamoto, Masayuki
Published in Molecular and Cellular Biology (01.04.2013)
Published in Molecular and Cellular Biology (01.04.2013)
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Journal Article
Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain
Sakai, Mai, Takeuchi, Hikaru, Yu, Zhiqian, Kikuchi, Yoshie, Ono, Chiaki, Takahashi, Yuta, Ito, Fumiaki, Matsuoka, Hiroo, Tanabe, Osamu, Yasuda, Jun, Taki, Yasuyuki, Kawashima, Ryuta, Tomita, Hiroaki
Published in Psychiatry and clinical neurosciences (01.06.2018)
Published in Psychiatry and clinical neurosciences (01.06.2018)
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Journal Article
Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project
Saito, Sakae, Aoki, Yuichi, Tamahara, Toru, Goto, Maki, Matsui, Hiroyuki, Kawashima, Junko, Danjoh, Inaho, Hozawa, Atsushi, Kuriyama, Shinichi, Suzuki, Yoichi, Fuse, Nobuo, Kure, Shigeo, Yamashita, Riu, Tanabe, Osamu, Minegishi, Naoko, Kinoshita, Kengo, Tsuboi, Akito, Shimizu, Ritsuko, Yamamoto, Masayuki
Published in Frontiers in cellular and infection microbiology (29.01.2021)
Published in Frontiers in cellular and infection microbiology (29.01.2021)
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Journal Article
Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals
Yamaguchi-Kabata, Yumi, Yasuda, Jun, Tanabe, Osamu, Suzuki, Yoichi, Kawame, Hiroshi, Fuse, Nobuo, Nagasaki, Masao, Kawai, Yosuke, Kojima, Kaname, Katsuoka, Fumiki, Saito, Sakae, Danjoh, Inaho, Motoike, Ikuko N, Yamashita, Riu, Koshiba, Seizo, Saigusa, Daisuke, Tamiya, Gen, Kure, Shigeo, Yaegashi, Nobuo, Kawaguchi, Yoshio, Nagami, Fuji, Kuriyama, Shinichi, Sugawara, Junichi, Minegishi, Naoko, Hozawa, Atsushi, Ogishima, Soichi, Kiyomoto, Hideyasu, Takai-Igarashi, Takako, Kinoshita, Kengo, Yamamoto, Masayuki
Published in Journal of human genetics (01.02.2018)
Published in Journal of human genetics (01.02.2018)
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Journal Article
Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project
Yasuda, Jun, Katsuoka, Fumiki, Danjoh, Inaho, Kawai, Yosuke, Kojima, Kaname, Nagasaki, Masao, Saito, Sakae, Yamaguchi-Kabata, Yumi, Tadaka, Shu, Motoike, Ikuko N, Kumada, Kazuki, Sakurai-Yageta, Mika, Tanabe, Osamu, Fuse, Nobuo, Tamiya, Gen, Higasa, Koichiro, Matsuda, Fumihiko, Yasuda, Nobufumi, Iwasaki, Motoki, Sasaki, Makoto, Shimizu, Atsushi, Kinoshita, Kengo, Yamamoto, Masayuki
Published in BMC genomics (24.07.2018)
Published in BMC genomics (24.07.2018)
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Journal Article
The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor
Zhou, X. Edward, Suino-Powell, Kelly M., Xu, Yong, Chan, Cee-Wah, Tanabe, Osamu, Kruse, Schoen W., Reynolds, Ross, Engel, James Douglas, Xu, H. Eric
Published in The Journal of biological chemistry (28.01.2011)
Published in The Journal of biological chemistry (28.01.2011)
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