Human mannose-binding lectin inhibitor prevents Shiga toxin–induced renal injury
Ozaki, Masayuki, Kang, Yulin, Tan, Ying Siow, Pavlov, Vasile I., Liu, Bohan, Boyle, Daniel C., Kushak, Rafail I., Skjoedt, Mikkel-Ole, Grabowski, Eric F., Taira, Yasuhiko, Stahl, Gregory L.
Published in Kidney international (01.10.2016)
Published in Kidney international (01.10.2016)
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Journal Article
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
Montoya, Skye, Bourcier, Jessie, Noviski, Mark, Lu, Hao, Thompson, Meghan C, Chirino, Alexandra, Jahn, Jacob, Sondhi, Anya K, Gajewski, Stefan, Tan, Ying Siow May, Yung, Stephanie, Urban, Aleksandra, Wang, Eric, Han, Cuijuan, Mi, Xiaoli, Kim, Won Jun, Sievers, Quinlan, Auger, Paul, Bousquet, Hugo, Brathaban, Nivetha, Bravo, Brandon, Gessner, Melissa, Guiducci, Cristiana, Iuliano, James N, Kane, Tim, Mukerji, Ratul, Reddy, Panga Jaipal, Powers, Janine, Sanchez Garcia de Los Rios, Mateo, Ye, Jordan, Barrientos Risso, Carla, Tsai, Daniel, Pardo, Gabriel, Notti, Ryan Q, Pardo, Alejandro, Affer, Maurizio, Nawaratne, Vindhya, Totiger, Tulasigeri M, Pena-Velasquez, Camila, Rhodes, Joanna M, Zelenetz, Andrew D, Alencar, Alvaro, Roeker, Lindsey E, Mehta, Sanjoy, Garippa, Ralph, Linley, Adam, Soni, Rajesh Kumar, Skånland, Sigrid S, Brown, Robert J, Mato, Anthony R, Hansen, Gwenn M, Abdel-Wahab, Omar, Taylor, Justin
Published in Science (American Association for the Advancement of Science) (02.02.2024)
Published in Science (American Association for the Advancement of Science) (02.02.2024)
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Journal Article
Epidermal Growth Factor Receptor (EGFR) Signaling Is a Key Mediator of Hormone-Induced Leukocyte Infiltration in the Pubertal Female Mammary Gland
Aupperlee, Mark D, Zhao, Yong, Tan, Ying Siow, Leipprandt, Jeffrey R, Bennett, Jessica, Haslam, Sandra Z, Schwartz, Richard C
Published in Endocrinology (Philadelphia) (01.06.2014)
Published in Endocrinology (Philadelphia) (01.06.2014)
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Journal Article
Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis
Zhu, Yirong, Aupperlee, Mark D, Zhao, Yong, Tan, Ying Siow, Kirk, Erin L, Sun, Xuezheng, Troester, Melissa A, Schwartz, Richard C, Haslam, Sandra Z
Published in Oncotarget (13.12.2016)
Published in Oncotarget (13.12.2016)
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Journal Article
Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet
Aupperlee, Mark D, Zhao, Yong, Tan, Ying Siow, Zhu, Yirong, Langohr, Ingeborg M, Kirk, Erin L, Pirone, Jason R, Troester, Melissa A, Schwartz, Richard C, Haslam, Sandra Z
Published in Breast cancer research : BCR (02.11.2015)
Published in Breast cancer research : BCR (02.11.2015)
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Journal Article
약화된 이미드 활성을 지닌 BTK를 분해하기 위한 이작용성 화합물
POWERS JANINE, NOVISKI MARK, ROUNTREE RYAN, TAN YING SIOW, GUIDUCCI CRISTIANA
Year of Publication 18.03.2024
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Year of Publication 18.03.2024
Patent
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts
Zhang, Deyi, Harris, Hailey M., Chen, Jonathan, Judy, Jen, James, Gabriella, Kelly, Aileen, McIntosh, Joel, Tenn-McClellan, Austin, Ambing, Eileen, Tan, Ying Siow, Lu, Hao, Gajewski, Stefan, Clifton, Matthew C., Yung, Stephanie, Robbins, Daniel W., Pirooznia, Mehdi, Skånland, Sigrid S., Gaglione, Erika, Mhibik, Maissa, Underbayev, Chingiz, Ahn, Inhye E., Sun, Clare, Herman, Sarah E. M., Noviski, Mark, Wiestner, Adrian
Published in Blood (30.03.2023)
Published in Blood (30.03.2023)
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Journal Article
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
Robbins, Daniel W., Noviski, Mark A., Tan, Ying Siow, Konst, Zef A., Kelly, Aileen, Auger, Paul, Brathaban, Nivetha, Cass, Robert, Chan, Ming Liang, Cherala, Ganesh, Clifton, Matthew C., Gajewski, Stefan, Ingallinera, Timothy G., Karr, Dane, Kato, Daisuke, Ma, Jun, McKinnell, Jenny, McIntosh, Joel, Mihalic, Jeff, Murphy, Brent, Panga, Jaipal Reddy, Peng, Ge, Powers, Janine, Perez, Luz, Rountree, Ryan, Tenn-McClellan, Austin, Sands, Arthur T., Weiss, Dahlia R., Wu, Jeffrey, Ye, Jordan, Guiducci, Cristiana, Hansen, Gwenn, Cohen, Frederick
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
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Journal Article
Pubertal high fat diet: effects on mammary cancer development
Zhao, Yong, Tan, Ying Siow, Aupperlee, Mark D, Langohr, Ingeborg M, Kirk, Erin L, Troester, Melissa A, Schwartz, Richard C, Haslam, Sandra Z
Published in Breast cancer research : BCR (01.01.2013)
Published in Breast cancer research : BCR (01.01.2013)
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BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY
GUIDUCCI, Cristiana, POWERS, Janine, ROUNTREE, Ryan, NOVISKI, Mark, TAN, Ying Siow
Year of Publication 22.05.2024
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Year of Publication 22.05.2024
Patent
Bifunctional compounds for degrading btk with diminished imid activity
GUIDUCCI Cristiana, TAN Ying Siow, NOVISKI Mark, ROUNTREE Ryan, POWERS Janine
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
Patent
BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY
GUIDUCCI, Cristiana, POWERS, Janine, ROUNTREE, Ryan, NOVISKI, Mark, TAN, Ying Siow
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
Patent
BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY
GUIDUCCI, Cristiana, POWERS, Janine, ROUNTREE, Ryan, NOVISKI, Mark, TAN, Ying Siow
Year of Publication 19.01.2023
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Year of Publication 19.01.2023
Patent
BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY
GUIDUCCI, CRISTIANA, TAN, YING SIOW, NOVISKI, MARK, POWERS, JANINE, ROUNTREE, RYAN
Year of Publication 19.01.2023
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Year of Publication 19.01.2023
Patent
Beverage and food production using Greek yogurt acid whey
Dohnalek, Margaret, Tan, Siow Ying, McDonagh, Dave, Kleinbach-Sauter, Heidi, Collins, Yvonne, Shadix, Kyle, Browne, Damian
Year of Publication 12.05.2020
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Year of Publication 12.05.2020
Patent