How to stomach an epigenetic insult: the gastric cancer epigenome
Padmanabhan, Nisha, Ushijima, Toshikazu, Tan, Patrick
Published in Nature reviews. Gastroenterology & hepatology (01.08.2017)
Published in Nature reviews. Gastroenterology & hepatology (01.08.2017)
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Mapping genomic and epigenomic evolution in cancer ecosystems
Ushijima, Toshikazu, Clark, Susan J, Tan, Patrick
Published in Science (American Association for the Advancement of Science) (24.09.2021)
Published in Science (American Association for the Advancement of Science) (24.09.2021)
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Comparative genomics of Cryptococcus neoformans var. grubii associated with meningitis in HIV infected and uninfected patients in Vietnam
Day, Jeremy N, Qihui, Seet, Thanh, Lam Tuan, Trieu, Phan Hai, Van, Anh Duong, Thu, Nha Hoang, Chau, Tran Thi Hong, Lan, Nguyen P H, Chau, Nguyen Van Vinh, Ashton, Philip M, Thwaites, Guy E, Boni, Maciej F, Wolbers, Marcel, Nagarajan, Niranjan, Tan, Patrick B O, Baker, Stephen
Published in PLoS neglected tropical diseases (14.06.2017)
Published in PLoS neglected tropical diseases (14.06.2017)
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Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
Kumar, Vikrant, Ramnarayanan, Kalpana, Sundar, Raghav, Padmanabhan, Nisha, Srivastava, Supriya, Koiwa, Mayu, Yasuda, Tadahito, Koh, Vivien, Huang, Kie Kyon, Tay, Su Ting, Ho, Shamaine Wei Ting, Tan, Angie Lay Keng, Ishimoto, Takatsugu, Kim, Guowei, Shabbir, Asim, Chen, Qingfeng, Zhang, Biyan, Xu, Shengli, Lam, Kong-Peng, Lum, Huey Yew Jeffrey, Teh, Ming, Yong, Wei Peng, So, Jimmy Bok Yan, Tan, Patrick
Published in Cancer discovery (01.03.2022)
Published in Cancer discovery (01.03.2022)
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A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters
Demircioğlu, Deniz, Cukuroglu, Engin, Kindermans, Martin, Nandi, Tannistha, Calabrese, Claudia, Fonseca, Nuno A., Kahles, André, Lehmann, Kjong-Van, Stegle, Oliver, Brazma, Alvis, Brooks, Angela N., Rätsch, Gunnar, Tan, Patrick, Göke, Jonathan
Published in Cell (05.09.2019)
Published in Cell (05.09.2019)
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A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma
Yang, Weiqin, Feng, Yu, Zhou, Jingying, Cheung, Otto Ka-Wing, Cao, Jianquan, Wang, Jing, Tang, Wenshu, Tu, Yalin, Xu, Liangliang, Wu, Feng, Tan, Zhiwu, Sun, Hanyong, Tian, Yuan, Wong, John, Lai, Paul Bo-San, Chan, Stephen Lam, Chan, Anthony Wing-Hung, Tan, Patrick Boon-Ooi, Chen, Zhiwei, Sung, Joseph Jao-Yiu, Yip, Kevin Yuk-Lap, To, Ka-Fai, Cheng, Alfred Sze-Lok
Published in Science translational medicine (07.04.2021)
Published in Science translational medicine (07.04.2021)
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Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance
Uchihara, Tomoyuki, Miyake, Keisuke, Yonemura, Atsuko, Komohara, Yoshihiro, Itoyama, Rumi, Koiwa, Mayu, Yasuda, Tadahito, Arima, Kota, Harada, Kazuto, Eto, Kojiro, Hayashi, Hiromitsu, Iwatsuki, Masaaki, Iwagami, Shiro, Baba, Yoshifumi, Yoshida, Naoya, Yashiro, Masakazu, Masuda, Mari, Ajani, Jaffer A, Tan, Patrick, Baba, Hideo, Ishimoto, Takatsugu
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
A STAT3-based gene signature stratifies glioma patients for targeted therapy
Tan, Melanie Si Yan, Sandanaraj, Edwin, Chong, Yuk Kien, Lim, See Wee, Koh, Lynnette Wei Hsien, Ng, Wai Hoe, Tan, Nguan Soon, Tan, Patrick, Ang, Beng Ti, Tang, Carol
Published in Nature communications (09.08.2019)
Published in Nature communications (09.08.2019)
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Journal Article
Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma
Okabe, Atsushi, Huang, Kie Kyon, Matsusaka, Keisuke, Fukuyo, Masaki, Xing, Manjie, Ong, Xuewen, Hoshii, Takayuki
Published in Nature genetics (01.09.2020)
Published in Nature genetics (01.09.2020)
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Journal Article
The draft genome of tropical fruit durian (Durio zibethinus)
Teh, Bin Tean, Lim, Kevin, Yong, Chern Han, Ng, Cedric Chuan Young, Rao, Sushma Ramesh, Rajasegaran, Vikneswari, Lim, Weng Khong, Ong, Choon Kiat, Chan, Ki, Cheng, Vincent Kin Yuen, Soh, Poh Sheng, Swarup, Sanjay, Rozen, Steven G, Nagarajan, Niranjan, Tan, Patrick
Published in Nature genetics (01.11.2017)
Published in Nature genetics (01.11.2017)
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Journal Article
STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation
Sheng, Wanqiang, Yang, Fan, Zhou, Yi, Yang, Henry, Low, Pey Yng, Kemeny, David Michael, Tan, Patrick, Moh, Akira, Kaplan, Mark H, Zhang, Yongliang, Fu, Xin-Yuan
Published in Cell research (01.12.2014)
Published in Cell research (01.12.2014)
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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
Yasuda, Tadahito, Koiwa, Mayu, Yonemura, Atsuko, Miyake, Keisuke, Kariya, Ryusho, Kubota, Sho, Yokomizo-Nakano, Takako, Yasuda-Yoshihara, Noriko, Uchihara, Tomoyuki, Itoyama, Rumi, Bu, Luke, Fu, Lingfeng, Arima, Kota, Izumi, Daisuke, Iwagami, Shiro, Eto, Kojiro, Iwatsuki, Masaaki, Baba, Yoshifumi, Yoshida, Naoya, Ohguchi, Hiroto, Okada, Seiji, Matsusaki, Keisuke, Sashida, Goro, Takahashi, Akiko, Tan, Patrick, Baba, Hideo, Ishimoto, Takatsugu
Published in Cell reports (Cambridge) (23.02.2021)
Published in Cell reports (Cambridge) (23.02.2021)
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Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer
Huang, Kie Kyon, Ramnarayanan, Kalpana, Zhu, Feng, Srivastava, Supriya, Xu, Chang, Tan, Angie Lay Keng, Lee, Minghui, Tay, Suting, Das, Kakoli, Xing, Manjie, Fatehullah, Aliya, Alkaff, Syed Muhammad Fahmy, Lim, Tony Kiat Hon, Lee, Jonathan, Ho, Khek Yu, Rozen, Steven George, Teh, Bin Tean, Barker, Nick, Chia, Chung King, Khor, Christopher, Ooi, Choon Jin, Fock, Kwong Ming, So, Jimmy, Lim, Wee Chian, Ling, Khoon Lin, Ang, Tiing Leong, Wong, Andrew, Rao, Jaideepraj, Rajnakova, Andrea, Lim, Lee Guan, Yap, Wai Ming, Teh, Ming, Yeoh, Khay Guan, Tan, Patrick
Published in Cancer cell (08.01.2018)
Published in Cancer cell (08.01.2018)
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Journal Article
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
Chan, Tim Hon Man, Qamra, Aditi, Tan, Kar Tong, Guo, Jing, Yang, Henry, Qi, Lihua, Lin, Jaymie Siqi, Ng, Vanessa Hui En, Song, Yangyang, Hong, Huiqi, Tay, Su Ting, Liu, Yujing, Lee, Jeeyun, Rha, Sun Yong, Zhu, Feng, So, Jimmy Bok Yan, Teh, Bin Tean, Yeoh, Khay Guan, Rozen, Steve, Tenen, Daniel G, Tan, Patrick, Chen, Leilei
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2016)
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Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer
Huang, Kie Kyon, Huang, Jiawen, Wu, Jeanie Kar Leng, Lee, Minghui, Tay, Su Ting, Kumar, Vikrant, Ramnarayanan, Kalpana, Padmanabhan, Nisha, Xu, Chang, Tan, Angie Lay Keng, Chan, Charlene, Kappei, Dennis, Göke, Jonathan, Tan, Patrick
Published in Genome Biology (22.01.2021)
Published in Genome Biology (22.01.2021)
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A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
Deng, Niantao, Goh, Liang Kee, Wang, Hannah, Das, Kakoli, Tao, Jiong, Tan, Iain Beehuat, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Lim, Kiat Hon, Lei, Zhengdeng, Goh, Glenn, Lim, Qing-Yan, Tan, Angie Lay-Keng, Sin Poh, Dianne Yu, Riahi, Sudep, Bell, Sandra, Shi, Michael M, Linnartz, Ronald, Zhu, Feng, Yeoh, Khay Guan, Toh, Han Chong, Yong, Wei Peng, Cheong, Hyun Cheol, Rha, Sun Young, Boussioutas, Alex, Grabsch, Heike, Rozen, Steve, Tan, Patrick
Published in Gut (01.05.2012)
Published in Gut (01.05.2012)
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