Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis
Tan, Josephine M.E., Cook, Emma C.L., van den Berg, Marlene, Scheij, Saskia, Zelcer, Noam, Loregger, Anke
Published in Atherosclerosis (01.02.2019)
Published in Atherosclerosis (01.02.2019)
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Control of murine brown adipocyte development by GATA6
Jun, Seoyoung, Angueira, Anthony R, Fein, Ethan C, Tan, Josephine M E, Weller, Angela H, Cheng, Lan, Batmanov, Kirill, Ishibashi, Jeff, Sakers, Alexander P, Stine, Rachel R, Seale, Patrick
Published in Developmental cell (06.11.2023)
Published in Developmental cell (06.11.2023)
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SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P
Hendrix, Sebastian, Tan, Josephine M E, Ndoj, Klevis, Kingma, Jenina, Valiloo, Masoud, Zijlstra, Lobke F, Ottenhoff, Roelof, Seidah, Nabil G, Loregger, Anke, Kober, Daniel L, Zelcer, Noam
Published in Molecular and cellular biology (2024)
Published in Molecular and cellular biology (2024)
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Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism
Loregger, Anke, Raaben, Matthijs, Nieuwenhuis, Joppe, Tan, Josephine M. E., Jae, Lucas T., van den Hengel, Lisa G., Hendrix, Sebastian, van den Berg, Marlene, Scheij, Saskia, Song, Ji-Ying, Huijbers, Ivo J., Kroese, Lona J., Ottenhoff, Roelof, van Weeghel, Michel, van de Sluis, Bart, Brummelkamp, Thijn, Zelcer, Noam
Published in Nature communications (28.02.2020)
Published in Nature communications (28.02.2020)
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Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity
Smith, Reuben L, Tan, Josephine M E, Jonker, Martijs J, Jongejan, Aldo, Buissink, Thomas, Veldhuijzen, Steve, van Kampen, Antoine H C, Brul, Stanley, van der Spek, Hans
Published in PloS one (02.11.2017)
Published in PloS one (02.11.2017)
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