Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47
Yang, Chong, Yokomori, Rui, Chua, Lee Hui, Tan, Shi Hao, Tan, Darren Qiancheng, Miharada, Kenichi, Sanda, Takaomi, Suda, Toshio
Published in The Journal of experimental medicine (05.12.2022)
Published in The Journal of experimental medicine (05.12.2022)
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Journal Article
Loss of METTL3 Attenuates BPDCN Response to PRMT5 Inhibition Via Interferon Signaling
Rethnam, Malini, Tan, Darren Qiancheng, Tan, Shi Hao, Ying, Li, Yang, Henry, Suda, Toshio
Published in Blood (05.11.2021)
Published in Blood (05.11.2021)
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Journal Article
PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells
Tan, Darren Qiancheng, Li, Ying, Yang, Chong, Li, Jia, Tan, Shi Hao, Chin, Desmond Wai Loon, Nakamura-Ishizu, Ayako, Yang, Henry, Suda, Toshio
Published in Cell reports (Cambridge) (26.02.2019)
Published in Cell reports (Cambridge) (26.02.2019)
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Journal Article
Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia
Matsumura, Takayoshi, Nakamura-Ishizu, Ayako, Muddineni, Siva Sai Naga Anurag, Tan, Darren Qiancheng, Wang, Chelsia Qiuxia, Tokunaga, Kenji, Tirado-Magallanes, Roberto, Sian, Stephanie, Benoukraf, Touati, Okuda, Tsukasa, Asou, Norio, Matsuoka, Masao, Osato, Motomi, Suda, Toshio
Published in Blood (22.10.2020)
Published in Blood (22.10.2020)
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Journal Article
The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
Ng, King Pan, Manjeri, Aditi, Lee, Lin Ming, Chan, Zhu En, Tan, Chin Yee, Tan, Qiancheng Darren, Majeed, A'Qilah, Lee, Kian Leong, Chuah, Charles, Suda, Toshio, Ong, S Tiong
Published in PloS one (11.10.2018)
Published in PloS one (11.10.2018)
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Journal Article
High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells
Takihara, Yuji, Nakamura-Ishizu, Ayako, Tan, Darren Qiancheng, Fukuda, Masahiro, Matsumura, Takayoshi, Endoh, Mitsuhiro, Arima, Yuichiro, Chin, Desmond Wai Loon, Umemoto, Terumasa, Hashimoto, Michihiro, Mizuno, Hidenobu, Suda, Toshio
Published in Blood advances (13.08.2019)
Published in Blood advances (13.08.2019)
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Journal Article
PRMT5 Inhibition Affects RNA Methylation and Is a Potential Therapeutic Target in BPDCN
Rethnam, Malini, Tan, Darren Qiancheng, Tan, Shi Hao, Ying, Li, Yang, Henry, Suda, Toshio
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation
Nakamura-Ishizu, Ayako, Chin, Desmond Wai Loon, Matsumura, Takayoshi, Tan, Darren Qiancheng, Mochizuki-Kashio, Makiko, Jianwen, Deng, Suda, Toshio
Published in Blood (13.05.2021)
Published in Blood (13.05.2021)
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Journal Article
Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia
Niibori-Nambu, Akiko, Wang, Chelsia Qiuxia, Chin, Desmond Wai Loon, Chooi, Jing Yuan, Hosoi, Hiroki, Sonoki, Takashi, Tham, Cheng-Yong, Nah, Giselle Sek Suan, Cirovic, Branko, Tan, Darren Qiancheng, Takizawa, Hitoshi, Sashida, Goro, Goh, Yufen, Tng, Jiaqi, Fam, Wee Nih, Fullwood, Melissa Jane, Suda, Toshio, Yang, Henry, Tergaonkar, Vinay, Taniuchi, Ichiro, Li, Shang, Chng, Wee Joo, Osato, Motomi
Published in Gene (30.11.2024)
Published in Gene (30.11.2024)
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Journal Article
Abstract 971: PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells
Tan, Darren Qiancheng, Li, Ying, Yang, Chong, Li, Jia, Tan, Shi Hao, Chin, Desmond W., Nakamura-Ishizu, Ayako, Yang, Henry, Suda, Toshio
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Loss of METTL3 attenuates blastic plasmacytoid dendritic cell neoplasm response to PRMT5 inhibition via IFN signaling
Rethnam, Malini, Tan, Darren Qiancheng, Tan, Shi Hao, Li, Jia, Yokomori, Rui, Li, Ying, Yang, Henry, Sanda, Takaomi, Suda, Toshio
Published in Blood advances (27.09.2022)
Published in Blood advances (27.09.2022)
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