Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice
Tan, Carina P, Feng, Yue, Zhou, Yun-Ping, Eiermann, George J, Petrov, Aleksandr, Zhou, Changyou, Lin, Songnian, Salituro, Gino, Meinke, Peter, Mosley, Ralph, Akiyama, Taro E, Einstein, Monica, Kumar, Sanjeev, Berger, Joel P, Mills, Sander G, Thornberry, Nancy A, Yang, Lihu, Howard, Andrew D
Published in Diabetes (New York, N.Y.) (01.08.2008)
Published in Diabetes (New York, N.Y.) (01.08.2008)
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Journal Article
Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists
Zhou, Changyou, Tang, Cheng, Chang, Eric, Ge, Min, Lin, Songnian, Cline, Eric, Tan, Carina P., Feng, Yue, Zhou, Yun-Ping, Eiermann, George J., Petrov, Aleksandr, Salituro, Gino, Meinke, Peter, Mosley, Ralph, Akiyama, Taro E., Einstein, Monica, Kumar, Sanjeev, Berger, Joel, Howard, Andrew D., Thornberry, Nancy, Mills, Sander G., Yang, Lihu
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Journal Article
Discovery of a receptor related to the galanin receptors
Lee, Dennis K, Nguyen, Tuan, O'Neill, Gary P, Cheng, Regina, Liu, Yang, Howard, Andrew D, Coulombe, Nathalie, Tan, Carina P, Tang-Nguyen, Anh-Thi, George, Susan R, O'Dowd, Brian F
Published in FEBS letters (05.03.1999)
Published in FEBS letters (05.03.1999)
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Journal Article
Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: Species-Specific Gene Expression
Tan, Carina P., Sano, Hideki, Iwaasa, Hisashi, Pan, Jie, Sailer, Andreas W., Hreniuk, Donna L., Feighner, Scott D., Palyha, Oksana C., Pong, Sheng-Shung, Figueroa, David J., Austin, Christopher P., Jiang, Michael M., Yu, Hong, Ito, Junko, Ito, Makoto, Ito, Masahiko, Guan, Xiao Ming, MacNeil, Douglas J., Kanatani, Akio, Van der Ploeg, Lex H.T., Howard, Andrew D.
Published in Genomics (San Diego, Calif.) (01.06.2002)
Published in Genomics (San Diego, Calif.) (01.06.2002)
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Journal Article
Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats
Shearman, Lauren P., Camacho, Ramon E., Sloan Stribling, D., Zhou, Dan, Bednarek, Maria A., Hreniuk, Donna L., Feighner, Scott D., Tan, Carina P., Howard, Andrew D., Van der Ploeg, Lex H.T., MacIntyre, D.Euan, Hickey, Gerard J., Strack, Alison M.
Published in European journal of pharmacology (15.08.2003)
Published in European journal of pharmacology (15.08.2003)
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Journal Article
Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors
McKee, Karen Kulju, Palyha, Oksana C, Feighner, Scott D, Hreniuk, Donna L, Tan, Carina P, Phillips, Michael S, Smith, Roy G, Van der Ploeg, Lex H. T, Howard, Andrew D
Published in Molecular endocrinology (Baltimore, Md.) (01.04.1997)
Published in Molecular endocrinology (Baltimore, Md.) (01.04.1997)
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Journal Article
Characterization of the bombesin-like peptide receptor family in primates
Sano, Hideki, Feighner, Scott D, Hreniuk, Donna L, Iwaasa, Hisashi, Sailer, Andreas W, Pan, Jie, Reitman, Marc L, Kanatani, Akio, Howard, Andrew D, Tan, Carina P
Published in Genomics (San Diego, Calif.) (01.07.2004)
Published in Genomics (San Diego, Calif.) (01.07.2004)
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Journal Article
Ligand Activation Domain of Human Orphan Growth Hormone (GH) Secretagogue Receptor (GHS-R) Conserved from Pufferfish to Humans
Palyha, Oksana C, Feighner, Scott D, Tan, Carina P, McKee, Karen Kulju, Hreniuk, Donna L, Gao, Ying-Duo, Schleim, Klaus D, Yang, Lihu, Morriello, Gregori J, Nargund, Ravi, Patchett, Arthur A, Howard, Andrew D, Smith, Roy G
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2000)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2000)
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Journal Article
Structural Requirements for the Activation of the Human Growth Hormone Secretagogue Receptor by Peptide and Nonpeptide Secretagogues
Feighner, Scott D, Howard, Andrew D, Prendergast, Kristine, Palyha, Oksana C, Hreniuk, Donna L, Nargund, Ravi, Underwood, Dennis, Tata, James R, Dean, Dennis C, Tan, Carina P, McKee, Karen Kulju, Woods, John W, Patchett, Arthur A, Smith, Roy G, Van der Ploeg, Lex H. T
Published in Molecular endocrinology (Baltimore, Md.) (01.01.1998)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.1998)
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Journal Article
3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists
Walsh, Shawn P., Severino, Alexandra, Zhou, Changyou, He, Jiafang, Liang, Gui-Bai, Tan, Carina P., Cao, Jin, Eiermann, George J., Xu, Ling, Salituro, Gino, Howard, Andrew D., Mills, Sander G., Yang, Lihu
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Journal Article
Identification and Characterization of a Second Melanin-Concentrating Hormone Receptor, MCH-2R
Sailer, Andreas W., Sano, Hideki, Zeng, Zhizhen, McDonald, Terrence P., Pan, Jie, Pong, Sheng-Shung, Feighner, Scott D., Tan, Carina P., Fukami, Takehiro, Iwaasa, Hisashi, Hreniuk, Donna L., Morin, Nancy R., Sadowski, Sharon J., Ito, Makoto, Ito, Masahiko, Bansal, Alka, Ky, Betty, Figueroa, David J., Jiang, Qingping, Austin, Christopher P., MacNeil, Douglas J., Ishihara, Akane, Ihara, Masaki, Kanatani, Akio, Lex H. T. Van der Ploeg, Howard, Andrew D., Liu, Qingyun
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2001)
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Journal Article
Cloning and Characterization of Two Human G Protein-Coupled Receptor Genes (GPR38 and GPR39) Related to the Growth Hormone Secretagogue and Neurotensin Receptors
McKee, Karen Kulju, Tan, Carina P., Palyha, Oksana C., Liu, Jim, Feighner, Scott D., Hreniuk, Donna L., Smith, Roy G., Howard, Andrew D., Van der Ploeg, Lex H.T.
Published in Genomics (San Diego, Calif.) (15.12.1997)
Published in Genomics (San Diego, Calif.) (15.12.1997)
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Journal Article
Cloning and Expression of a Novel Neuropeptide Y Receptor
Weinberg, David H., Sirinathsinghji, Dalip J.S., Tan, Carina P., Shiao, Lin-Lin, Morin, Nancy, Rigby, Michael R., Heavens, Robert H., Rapoport, Davida R., Bayne, Marvin L., Cascieri, Margaret A., Strader, Catherine D., Linemeyer, David L., MacNeil, Douglas J.
Published in The Journal of biological chemistry (12.07.1996)
Published in The Journal of biological chemistry (12.07.1996)
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Journal Article
Molecular analysis of a new splice variant of the human melanocortin-1 receptor
Tan, Carina P, Kulju McKee, Karen, Weinberg, David H, MacNeil, Tanya, Palyha, Oksana C, Feighner, Scott D, Hreniuk, Donna L, Van Der Ploeg, Lex H.T, MacNeil, Douglas J, Howard, Andrew D
Published in FEBS letters (21.05.1999)
Published in FEBS letters (21.05.1999)
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Journal Article
A Role for the Melanocortin 4 Receptor in Sexual Function
Lex H. T. Van der Ploeg, Martin, William J., Howard, Andrew D., Nargund, Ravi P., Austin, Christopher P., Guan, Xiaoming, Drisko, Jennifer, Cashen, Doreen, Sebhat, Iyassu, Patchett, Arthur A., Figueroa, David J., DiLella, Anthony G., Connolly, Brett M., Weinberg, David H., Tan, Carina P., Palyha, Oksana C., Pong, Sheng-Shung, MacNeil, Tanya, Rosenblum, Charles, Vongs, Aurawan, Tang, Rui, Yu, Hong, Sailer, Andreas W., Fong, Tung Ming, Huang, Cathy, Tota, Michael R., Chang, Ray S., Stearns, Ralph, Tamvakopoulos, Constantin, Christ, George, Drazen, Deborah L., Spar, Brian D., Nelson, Randy J., MacIntyre, D. Euan
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
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Journal Article
Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analog
Lacourciere, Gerard M, Vakharia, Vikram N, Tan, Carina P, Morris, Diane I, Edwards, Gerard H, Moos, Malcolm, Armstrong, Richard N
Published in Biochemistry (Easton) (16.03.1993)
Published in Biochemistry (Easton) (16.03.1993)
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Journal Article
Identification of receptors for neuromedin U and its role in feeding
Liu, Qingyun, Howard, Andrew D, Wang, Ruiping, Pong, Sheng-Shung, Mellin, Theodore N, Strack, Alison, Guan, Xiao-Ming, Zeng, Zhizhen, Williams, David L, Feighner, Scott D, Nunes, Christian N, Murphy, Beth, Stair, Judith N, Yu, Hong, Jiang, Qingping, Clements, Michelle K, Tan, Carina P, McKee, Karen K, Hreniuk, Donna L, McDonald, Terrence P, Lynch, Kevin R, Evans, Jilly F, Austin, Christopher P, Caskey, C. Thomas, Van der Ploeg, Lex H. T
Published in Nature (London) (06.07.2000)
Published in Nature (London) (06.07.2000)
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Journal Article
Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase gene
Molowa, David T, Chen, William S, Cimis, George M, Tan, Carina P
Published in Biochemistry (Easton) (01.03.1992)
Published in Biochemistry (Easton) (01.03.1992)
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Journal Article
Receptor for Motilin Identified in the Human Gastrointestinal System
Feighner, Scott D., Tan, Carina P., McKee, Karen Kulju, Palyha, Oksana C., Hreniuk, Donna L., Pong, Sheng-Shung, Austin, Christopher P., Figueroa, David, MacNeil, Douglas, Cascieri, Margaret A., Nargund, Ravi, Bakshi, Raman, Abramovitz, Mark, Stocco, Rino, Kargman, Stacia, O'Neill, Gary, Lex H. T. Van Der Ploeg, Evans, Jilly, Patchett, Arthur A., Smith, Roy G., Howard, Andrew D.
Published in Science (American Association for the Advancement of Science) (25.06.1999)
Published in Science (American Association for the Advancement of Science) (25.06.1999)
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Journal Article
Molecular Characterization and Expression of Cloned Human Galanin Receptors GALR2 and GALR3
Kolakowski, Lee F., O'Neill, Gary P., Howard, Andrew D., Broussard, Suzanne R., Sullivan, Kathleen A., Feighner, Scott D., Sawzdargo, Marek, Nguyen, Tuan, Kargman, Stacia, Shiao, Lin‐Lin, Hreniuk, Donna L., Tan, Carina P., Evans, Jilly, Abramovitz, Mark, Chateauneuf, Anne, Coulombe, Nathalie, Ng, Gordon, Johnson, Michael P., Tharian, Anita, Khoshbouei, Habibeh, George, Susan R., Smith, Roy G., O'Dowd, Brian F.
Published in Journal of neurochemistry (01.12.1998)
Published in Journal of neurochemistry (01.12.1998)
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